46 Matching Annotations
  1. Aug 2025
  2. www.biorxiv.org www.biorxiv.org
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers | EMBO reports
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332006/
  4. Jul 2025
  5. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  6. www.embopress.org www.embopress.org
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
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    embopress.org/doi/10.1038/s44319-025-00511-8
  7. Jun 2025
  8. www.sciencedirect.com www.sciencedirect.com
    Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
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    sciencedirect.com/science/article/pii/S1535610825002533
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122438/
  10. www.sciencedirect.com www.sciencedirect.com
    Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy
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    sciencedirect.com/science/article/pii/S1934590925001870
  11. www.sciencedirect.com www.sciencedirect.com
    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002332
  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The 9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017600/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225008168-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
  16. www.sciencedirect.com www.sciencedirect.com
    Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery
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    sciencedirect.com/science/article/pii/S2667237525000852
  17. Apr 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  20. www.sciencedirect.com www.sciencedirect.com
    Protocol for the generation and assessment of functional macrophages from mouse bone marrow cells
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    sciencedirect.com/science/article/pii/S2666166725001121
  21. Mar 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927390/
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13820
  24. Feb 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
  26. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
  27. Jan 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747858/
  29. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Skin disease-associated GJB4 variants differentially influence connexin stability, cell viability and channel function
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP286367
  30. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/5d518fe67b29a1167ac13378ea5b10438a194286/PDF-html.html
  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cannabidiol promotes apoptosis and downregulation of oncogenic factors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642769/
  33. www.sciencedirect.com www.sciencedirect.com
    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    sciencedirect.com/science/article/pii/S1074761324005132
  34. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  35. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC10842433/
  39. Jul 2024
  40. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  41. Jun 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
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    sciencedirect.com/science/article/pii/S2211124724006417
  43. Mar 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542885/
  45. Feb 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870121/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  48. Jan 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
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    sciencedirect.com/science/article/pii/S2211124723016388
  50. Dec 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe
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    ncbi.nlm.nih.gov/pmc/articles/PMC10734389/
  53. Nov 2023
  54. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    sciencedirect.com/science/article/pii/S2589004223023647
  55. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  56. Sep 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10472104/
  58. Aug 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Characterization and Phase 1 Trial Results of INBRX-109, a Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425732/
  60. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  61. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
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    52.53.155.43/ea1e2390c2d37ea00d2075acaef6f5d93e41dc17/can-23-1252-html.html
  62. 52.53.155.43 52.53.155.43
    mcr-22-0916-html.html
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    52.53.155.43/ee24162242ef05486fd8a6e1481e2011af4e24fe/mcr-22-0916-html.html
  63. Jul 2023
  64. 52.53.155.43 52.53.155.43
    ccr-23-0974-html.html
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    52.53.155.43/56e27762e21f3d334d316ca546c7d609a39dce36/ccr-23-0974-html.html