85 Matching Annotations
  1. Sep 2026
  2. 54.241.53.176 54.241.53.176
    mct-25-1360-html.html
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    54.241.53.176/4d8acaa82df0b1249261f97f03c5b6ff417be932/mct-25-1360-html.html
  3. Aug 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13482947/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    E3 Ubiquitin Ligase Mindbomb1 Is a Novel Negative Regulator of Tumor-Suppressive BMP Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13489675/
  6. Jul 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of Glypican 3–Targeting Antibody–Drug Conjugates for Hepatocellular Carcinoma Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13366411/
  8. www.sciencedirect.com www.sciencedirect.com
    Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers
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    sciencedirect.com/science/article/pii/S2666379126003393
  9. aacrjournals.org aacrjournals.org
    Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Anti-tumor Immunity
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    aacrjournals.org/cancerres/article/86/5/1252/774876/Antibody-Mediated-Targeting-of-Secretory-Protein
  10. www.biorxiv.org www.biorxiv.org
    A Glutamine antagonist-modulated tumor microenvironment unleashes enzalutamide’s immunotherapeutic effects
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    biorxiv.org/content/10.64898/2026.06.30.735585v1
  11. Jun 2026
  12. aacrjournals.org aacrjournals.org
    Human kallikrein 2: A novel lineage-specific surface target in prostate cancer
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    aacrjournals.org/clincancerres/article/31/21/4543/766834/Human-Kallikrein-2-A-Novel-Lineage-Specific
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13226670/
  14. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis reveals Rho kinase addiction as a vulnerability of de-differentiated cancer cells
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    sciencedirect.com/science/article/pii/S2589004226014069
  15. May 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual Inhibition of TRIP13 and Aurora A Induces Mitotic DNA Damage and Concurrent Pyroptotic-apoptotic Cell Death in Rb-deficient Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13189064/
  17. 54.241.53.176 54.241.53.176
    Metabolic plasticity and optimal redox homeostasis are essential for efficient metastatic colonization
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    54.241.53.176/4dbff441f5e8f4c01ee4cd1c59e7e9c4d3f2694e/1-s2.0-S2212877826000669-main-html.html
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lipid Composition Alters Ferroptosis Sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138121/
  19. Apr 2026
  20. www.sciencedirect.com www.sciencedirect.com
    GLIS3 marks a neural-like progenitor cell state that drives metastasis in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S221112472600392X
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Myofibroblasts induce neuroplasticity to promote pancreatic inflammation and cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13102267/
  22. aacrjournals.org aacrjournals.org
    Tunneling CARs: Increasing CAR T-cell tumor infiltration through the overexpression of MMP-7 and Osteopontin-b
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    aacrjournals.org/cancerimmunolres/article/13/11/1732/766804/Tunneling-CARs-Increasing-CAR-T-Cell-Tumor
  23. aacrjournals.org aacrjournals.org
    A universal boosting strategy for adoptive T cell therapy using a paired vaccine/chimeric antigen receptor
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    aacrjournals.org/cancerimmunolres/article/14/2/261/771969/A-Universal-Boosting-Strategy-for-Adoptive-T-cell
  24. 54.241.53.176 54.241.53.176
    cd-25-1337-html.html
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    54.241.53.176/d16861070c75210d6af0553cc182ded0fb9185e8/cd-25-1337-html.html
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An antibody-drug conjugate designed through clone and isotype selection restricts the growth of CSPG4-expressing triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13096323/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080321/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BESTDR Enables Bayesian Quantification of Mechanism-Specific Drug Responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055639/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039881/
  29. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521101
  30. Mar 2026
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012245/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ORMDL Proteins Turnover via Proteasome and Autophagy Is Cell‐Type Dependent and Tied to Ceramide Homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974560/
  33. www.sciencedirect.com www.sciencedirect.com
    Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy
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    sciencedirect.com/science/article/pii/S009286742600173X
  34. Feb 2026
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of the FGF8/FGF receptor signaling pathway in the maintenance and progression of fusion-positive rhabdomyosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12928154/
  36. www.sciencedirect.com www.sciencedirect.com
    Syndecan-1-targeted therapeutic antibody impairs macropinocytosis and elicits antitumor immunity in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2666379126000303
  37. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226002336-main-html.html
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    54.241.53.176/e86b13a815c53c6ac4146180b2283f50e62e856a/1-s2.0-S2589004226002336-main-html.html
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Navitoclax, a Bcl-2/xL inhibitor, and YM155, a survivin inhibitor, in combination with carboplatin, effectively inhibit ovarian cancer tumor growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12316570/
  39. Jan 2026
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A High-Fiber Plant-Based Diet in Myeloma Precursor Disorders – Results from the NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12811828/
  41. Dec 2025
  42. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70294
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immunomodulatory effects of lenvatinib in patients with advanced thyroid cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12717327/
  44. 54.241.53.176 54.241.53.176
    s12885-025-15319-x_reference-html.html
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    54.241.53.176/395576a1a6be1c7cc7df0ab1f5fdf52cac977205/s12885-025-15319-x_reference-html.html
  45. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Protocol for the generation of three-dimensional micropatterned neuroepithelial tissues using hPSCs, bioprinting, and matrix scaffolds
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    sciencedirect.com:5037/science/article/pii/S2666166725006021
  46. Nov 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591092/
  48. Oct 2025
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interactions Between Ploidy and Resource Availability Shape Clonal Evolution in Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12261341/
  50. Sep 2025
  51. www.sciencedirect.com www.sciencedirect.com
    High-throughput bioprinting to produce micropatterened neuroepithelial tissues and model TSC2-deficient brain malformations
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    sciencedirect.com/science/article/pii/S2667237525002139
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Resilience and vulnerabilities of tumor cells under purine shortage stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399269/
  53. Aug 2025
  54. www.biorxiv.org www.biorxiv.org
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers | EMBO reports
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    pmc.ncbi.nlm.nih.gov/articles/PMC12332006/
  56. Jul 2025
  57. www.sciencedirect.com www.sciencedirect.com
    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
  58. www.embopress.org www.embopress.org
    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
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    embopress.org/doi/10.1038/s44319-025-00511-8
  59. Jun 2025
  60. www.sciencedirect.com www.sciencedirect.com
    Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
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    sciencedirect.com/science/article/pii/S1535610825002533
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12122438/
  62. www.sciencedirect.com www.sciencedirect.com
    Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy
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    sciencedirect.com/science/article/pii/S1934590925001870
  63. www.sciencedirect.com www.sciencedirect.com
    Screening a living biobank identifies cabazitaxel as a strategy to combat acquired taxol resistance in high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002332
  64. May 2025
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12087151/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The 9p21.3 Coronary Artery Disease Risk Locus Drives Vascular Smooth Muscle Cells to an Osteochondrogenic State
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017600/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225008168-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
  68. www.sciencedirect.com www.sciencedirect.com
    Generation of T cell responses against broad KRAS hotspot neoantigens for cell therapy or TCR discovery
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    sciencedirect.com/science/article/pii/S2667237525000852
  69. Apr 2025
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11967718/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  72. www.sciencedirect.com www.sciencedirect.com
    Protocol for the generation and assessment of functional macrophages from mouse bone marrow cells
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    sciencedirect.com/science/article/pii/S2666166725001121
  73. Mar 2025
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11927390/
  75. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13820
  76. Feb 2025
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC11850729/
  78. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/f141eddf8d6ed9d4f64a9be0f6055059836b8d11/PDF-html.html
  79. Jan 2025
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747858/
  81. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Skin disease-associated GJB4 variants differentially influence connexin stability, cell viability and channel function
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP286367
  82. 52.53.155.43 52.53.155.43
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    52.53.155.43/5d518fe67b29a1167ac13378ea5b10438a194286/PDF-html.html
  83. Dec 2024
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cannabidiol promotes apoptosis and downregulation of oncogenic factors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11642769/
  85. www.sciencedirect.com www.sciencedirect.com
    Microglial lipid phosphatase SHIP1 limits complement-mediated synaptic pruning in the healthy developing hippocampus
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    sciencedirect.com/science/article/pii/S1074761324005132
  86. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  87. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  88. Aug 2024
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292198/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC10842433/
  91. Jul 2024
  92. 52.53.155.43 52.53.155.43
    Endoplasmic reticulum morphology regulation by RTN4 modulates neuronal regeneration by curbing luminal transport
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    52.53.155.43/a5cd2a76f55670a4ac26cd7a0c2f7cbc81f1256c/Endoplasmic reticulum morphology regulation by RTN4 modulates neu-html.html
  93. Jun 2024
  94. www.sciencedirect.com www.sciencedirect.com
    Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform
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    sciencedirect.com/science/article/pii/S2211124724006417
  95. Mar 2024
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a ΔNp63-Dependent Basal-Like A Subtype-Specific Transcribed Enhancer Program (B-STEP) in Aggressive Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10542885/
  97. Feb 2024
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870121/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  100. Jan 2024
  101. www.sciencedirect.com www.sciencedirect.com
    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
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    sciencedirect.com/science/article/pii/S2211124723016388
  102. Dec 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe
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    ncbi.nlm.nih.gov/pmc/articles/PMC10734389/
  105. Nov 2023
  106. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    sciencedirect.com/science/article/pii/S2589004223023647
  107. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  108. Sep 2023
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10472104/
  110. Aug 2023
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Characterization and Phase 1 Trial Results of INBRX-109, a Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425732/
  112. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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  113. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
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  114. 52.53.155.43 52.53.155.43
    mcr-22-0916-html.html
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  115. Jul 2023
  116. 52.53.155.43 52.53.155.43
    ccr-23-0974-html.html
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    52.53.155.43/56e27762e21f3d334d316ca546c7d609a39dce36/ccr-23-0974-html.html