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Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

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1. scibot 14 Dec 2025
  
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  DOI: 10.1038/s42255-025-01415-6
  
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nature.com/articles/s42255-025-01415-6
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Dnmt3a2 expression during embryonic development is required for phenotypic stability

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1. scibot 11 Dec 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1038/s42003-025-09311-1
  
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nature.com/articles/s42003-025-09311-1
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Seed structure and phosphorylation in the fuzzy coat impact tau seeding competency

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1. scibot 21 Oct 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1038/s41467-025-64312-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12534512/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The E3 ubiquitin ligase Trip12 semi-selectively attenuates Wnt signaling

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1. scibot 16 Oct 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1016/j.isci.2025.113575
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519312/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Secreted Frizzled-Related Protein 1a regulates hematopoietic development in a dose-dependent manner

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.ydbio.2025.09.019
  
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sciencedirect.com/science/article/pii/S0012160625002775
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An alternative route for β-hydroxybutyrate metabolism supports cytosolic acetyl-CoA synthesis in cancer cells

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1. scibot 18 Sep 2025
  
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  DOI: 10.1038/s42255-025-01366-y
  
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nature.com/articles/s42255-025-01366-y
www.biorxiv.org www.biorxiv.org

EHMT2 Controls Neural Crest-Derived Craniofacial Development but is Dispensable in Limb Development

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1. scibot 18 Sep 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1101/2025.09.07.674526
  
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biorxiv.org/content/10.1101/2025.09.07.674526v1
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dnmt3a2 expression during embryonic development is required for phenotypic stability

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1. scibot 22 Jul 2025
  
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  RRID:SCR_023211
  
  DOI: 10.21203/rs.3.rs-6908216/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12236915/
www.nature.com www.nature.com

High-coverage allele-resolved single-cell DNA methylation profiling reveals cell lineage, X-inactivation state, and replication dynamics

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1. scibot 15 Jul 2025
  
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  DOI: 10.1038/s41467-025-61589-1
  
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nature.com/articles/s41467-025-61589-1
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The prostacyclin receptor PTGIR is a NRF2-dependent regulator of CD8+ T cell exhaustion

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1. scibot 02 Jul 2025
  
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  DOI: 10.1038/s41590-025-02185-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12208871/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathological α-synuclein elicits granulovacuolar degeneration independent of tau

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1. scibot 25 Jun 2025
  
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  DOI: 10.1186/s40035-025-00494-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12177994/
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development

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1. scibot 20 Mar 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1038/s41467-025-57926-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11909213/
Jan 2025
journals.sagepub.com journals.sagepub.com

Chronic urinary tract infections cause persistent microglial changes in a humanized ɑ-synuclein mouse model

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1. scibot 04 Jan 2025
  
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  RRID:SCR_023211
  
  DOI: 10.1177/1877718X241289046
  
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journals.sagepub.com/doi/full/10.1177/1877718X241289046
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A potent and selective ENL degrader suppresses oncogenic gene expression and leukemia progression

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1. scibot 30 Aug 2024
  
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  DOI: 10.1126/sciadv.ado1432
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11352836/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114506
  
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sciencedirect.com/science/article/pii/S2211124724008350
May 2024
www.biorxiv.org www.biorxiv.org

Adult-Onset Deletion of ATP13A2 in Mice Induces Progressive Nigrostriatal Pathway Dopaminergic Degeneration and Lysosomal Abnormalities

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1. scibot 10 May 2024
  
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  DOI: 10.1101/2024.01.25.577280
  
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biorxiv.org/content/10.1101/2024.01.25.577280v1
Feb 2024
www.biorxiv.org www.biorxiv.org

Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

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1. scibot 02 Feb 2024
  
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  DOI: 10.1101/2024.01.10.574969
  
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biorxiv.org/content/10.1101/2024.01.10.574969v1
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

β-catenin-dependent High Bone Mass Induced by Loss of APC in Osteoblasts Does Not Require Lrp5 or Lrp6

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1. scibot 02 Nov 2023
  
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  RRID:SCR_023211
  
  DOI: 10.17912/micropub.biology.001000
  
  Resource: Van Andel Institute Vivarium Core Facility (RRID:SCR_023211)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10613880/
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Developmental priming of cancer susceptibility

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1. scibot 05 Oct 2023
  
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  RRID:SCR_023211
  
  DOI: 10.1101/2023.09.12.557446
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10515831/