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Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

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1. scibot 27 Sep 2025
  
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  RRID:SCR_025231
  
  DOI: 10.1016/j.immuni.2025.09.003
  
  Resource: University of North Carolina at Chapel Hill Translational Genomics Lab Core Facility (RRID:SCR_025231)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_025231
  
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sciencedirect.com/science/article/pii/S1074761325004145
Jun 2025
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A first-in-class EGFR-directed KRAS G12V selective inhibitor

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1. scibot 21 Jun 2025
  
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  RRID:SCR_025231
  
  DOI: 10.1016/j.ccell.2025.05.016
  
  Resource: University of North Carolina at Chapel Hill Translational Genomics Lab Core Facility (RRID:SCR_025231)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_025231
  
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sciencedirect.com/science/article/pii/S1535610825002259
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Snord67 promotes breast cancer metastasis by guiding U6 modification and modulating the splicing landscape

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1. scibot 19 May 2025
  
  in Public
  
  RRID:SCR_025231
  
  DOI: 10.1038/s41467-025-59406-w
  
  Resource: University of North Carolina at Chapel Hill Translational Genomics Lab Core Facility (RRID:SCR_025231)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_025231
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12048515/
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Differential Localization of β-catenin Protein in CTNNB1 Mutant Endometrial Cancers Results in Distinct Transcriptional Profiles

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1. scibot 18 May 2025
  
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  RRID:SCR_025231
  
  DOI: 10.1016/j.modpat.2025.100791
  
  Resource: University of North Carolina at Chapel Hill Translational Genomics Lab Core Facility (RRID:SCR_025231)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_025231
  
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  RRID:SCR_025231
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RRID:SCR_025231

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sciencedirect.com/science/article/pii/S0893395225000870