47 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p38 MAPK and MDT-15 mediate SKN-1-dependent metformin-induced protection against mitis group streptococci in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC13638828/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic analysis of sensitivity to temperature fluctuations identifies acclimation stress as a novel type of cellular stress in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC13535214/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Nematicide Tioxazafen Disrupts Proteasome Function via Cytochrome P450 Bioactivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13405185/
  5. Sep 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gas-sensing neurons prime mitochondrial fitness to offset metabolic stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12974494/
  7. Jun 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Examining Sporadic Cancer Mutations Uncovers a Set of Genes Involved in Mitochondrial Maintenance
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    pmc.ncbi.nlm.nih.gov/articles/PMC10218105/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Local coordination of mRNA storage and degradation near mitochondria modulates C. elegans ageing
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    pmc.ncbi.nlm.nih.gov/articles/PMC10425844/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Casein kinase 1 gamma regulates oxidative stress response via interacting with the NADPH dual oxidase complex
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    pmc.ncbi.nlm.nih.gov/articles/PMC10166522/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glia of C. elegans coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC9733925/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The metabolite alpha-ketobutyrate extends lifespan by promoting peroxisomal function in C. elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC9842765/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondria hormesis delays aging and associated diseases in Caenorhabditis elegans impacting on key ferroptosis players
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    pmc.ncbi.nlm.nih.gov/articles/PMC10067770/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial succinate dehydrogenase (SDHA) function is essential for sperm motility and male fertility
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    pmc.ncbi.nlm.nih.gov/articles/PMC9709242/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A transcriptional cofactor regulatory network for the C. elegans intestine
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    pmc.ncbi.nlm.nih.gov/articles/PMC10320766/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative analysis of the molecular and physiological consequences of constitutive SKN-1 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10643742/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reductive death is averted by a conserved de novo lipogenic switch
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    pmc.ncbi.nlm.nih.gov/articles/PMC13386819/
  18. Apr 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic effects of chemical mixtures on the oxidative stress response are silenced by heat stress and reversed under dietary restriction
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    pmc.ncbi.nlm.nih.gov/articles/PMC12525721/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Urolithin Α modulates inter-organellar communication via calcium-dependent mitophagy to promote healthy ageing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758194/
  21. Dec 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Growth on stiffer substrates impacts animal health and longevity in C. elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC11392421/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gas-sensing neurons prime mitochondrial fitness to offset metabolic stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC12262713/
  24. Nov 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Environmental NaCl affects C. elegans development and aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952357/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thiostrepton induces apoptotic cell death at the level of BCL-2/CED-9 in C. elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238647/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC11265709/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extracellular vesicles from the microalga Tetraselmis chuii are biocompatible and exhibit unique bone tropism along with antioxidant and anti-inflammatory properties
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    pmc.ncbi.nlm.nih.gov/articles/PMC11297973/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC11493899/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Caenorhabditis elegans proteome response to two protective Pseudomonas symbionts
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    pmc.ncbi.nlm.nih.gov/articles/PMC11005407/
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Different gametogenesis states uniquely impact longevity in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC12541034/
  32. Oct 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12251208/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11838306/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Towards the development of phytoextract based healthy ageing cognitive booster formulation, explored through Caenorhabditis elegans model
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    pmc.ncbi.nlm.nih.gov/articles/PMC9649024/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structure−activity relationship of ginsenoside derivatives with different glycosides and double bond position on anti-aging bioactivities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12365557/
  37. Jan 2025
  38. www.sciencedirect.com www.sciencedirect.com
    Temperature perception by ER UPR promotes preventive innate immunity and longevity
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    sciencedirect.com/science/article/pii/S2211124724014220
  39. Nov 2024
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Seawater Accelerated the Aging of Polystyrene and Enhanced Its Toxic Effects on Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC10743734/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SKN‐1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC10928581/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging
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    pmc.ncbi.nlm.nih.gov/articles/PMC10721613/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dendrobium Nobile Alcohol Extract Extends the Lifespan of Caenorhabditis elegans via hsf-1 and daf-16
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    pmc.ncbi.nlm.nih.gov/articles/PMC10891841/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans
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    pmc.ncbi.nlm.nih.gov/articles/PMC11004342/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro and In Vivo Insights into a Broccoli Byproduct as a Healthy Ingredient for the Management of Alzheimer’s Disease and Aging through Redox Biology
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    pmc.ncbi.nlm.nih.gov/articles/PMC10941188/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Poplar Bud (Populus) Extraction and Chinese Propolis Counteract Oxidative Stress in Caenorhabditis elegans via Insulin/IGF-1 Signaling Pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11274317/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    P-hydroxybenzaldehyde protects Caenorhabditis elegans from oxidative stress and β-amyloid toxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11150654/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4,4′-methylenediphenol reduces Aβ-induced toxicity in a Caenorhabditis elegans model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11171718/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring the therapeutic potential of Nelumbo nucifera leaf extract against amyloid-beta-induced toxicity in the Caenorhabditis elegans model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11232431/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cysteine protease cathepsin B promotes lysosome integrity to extend the lifespan of alternative day fasting worms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11561666/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A high-throughput screening platform for discovering bacterial species and small molecules that modify animal physiology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11092615/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel ferroptosis inhibitor, Thonningianin A, improves Alzheimer's disease by activating GPX4
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11488096/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TSG Extends the Longevity of Caenorhabditis elegans by Targeting the DAF-16/SKN-1/SIR-2.1-Mediated Mitochondrial Quality Control Process
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    pmc.ncbi.nlm.nih.gov/articles/PMC11428426/
  54. Jul 2024
  55. www.sciencedirect.com www.sciencedirect.com
    The extracellular matrix integrates mitochondrial homeostasis
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    sciencedirect.com/science/article/pii/S009286742400638X
  56. May 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-dose Naltrexone (LDN) extends healthspan and lifespan in C. elegans via SKN-1 activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11126937/
  58. Aug 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Tribbles pseudokinase NIPI-3 regulates intestinal immunity in Caenorhabditis elegans by controlling SKN-1/Nrf activity
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    sciencedirect.com/science/article/pii/S2211124721009608