- Nov 2017
The most common eye finding in congenital toxoplasmosis is the presence of chorioretinal scars, reported in 79% of patients. These scars may occur anywhere in the retina but with a higher incidence in the macula.
Ocular findings in Congenital Toxoplasomsis:
- 79% patients have chorioretinal scars *Scar may involve macula with significant decrease in visual acuity
- scar may involve periheral area with decreased acuity by dragging of macula
Chorioretinal scar in congenital toxoplasmosis
Other posterior ocular complications include:
- retinal attachment and active chorioretinitis in 10%
- Optic atrophy in 20%
- Other findings may include: cataracts, microphtalmia, microcornea, nystagmus.
Classic triad of findings in congenital toxoplasmosis includes:
- hydrocephalus, and
- intracranial calcifications.
See also: Toxoplasmosis- AAPOS
What are the symptoms of newly acquired toxoplasmosis in an adult?
More than 80% of newly infected persons experience no symptoms, and are unlikely to be aware of the infection.
Symptoms may occur following an incubation period of one to two weeks after exposure and include:
*muscle and/or joint pain
*sore throat, and
*Eye symptoms may include blurred vision or floaters during active disease.
The diagnosis can be confirmed by detecting antibodies to Toxoplasma in the blood. Swelling of the liver or spleen may be noted, and in rare cases the lungs, brain, liver, or heart may be involved. The condition usually resolves without treatment within a few months.
Toxoplasmosis is caused by the obligate intracellular parasite, Toxoplasma gondii. Its life cycle consists of 3 forms, including an oocyst, a tissue cyst, and an active (proliferative) form.
See also: CDC- Toxoplasmosis
Source of Infection in humans:
- Eating under cooked meat of animals harboring tissue cysts
- Consuming food or water contaminated with cat feces or by contaminated environmental samples (such as fecal-contaminated soil or changing the litter box of a pet cat)
- Blood transfusion or organ transplantation
- Transplacentally from mother to fetus
Sources of T. gondi infection
Life cycle of T. gondi
- Maternal Toxoplasmosis
- congenital toxoplasmosis
- Tissue cysts
- T. gondii
- ocular findings
- classic triad
- Life Cycle
- fundus in normal retina
- source of infection
- symptoms in mother
- fundus in congenital toxo with chorioretinal scar