The discussion at Brutus' home in Act II Scene I revealed that there was much fear surrounding Antonius' reaction to Caesar's death. Trebonius was the only conspirator to agree with Brutus that Mark Antony did not pose a threat, instead remarking that '"There is no fear in him; let him not die; For he will live, and laugh at this hereafter." However, this act of compassion would eventually lead to the conspirators' downfall.

Therefore, Trebonius' conspiratorial role was to lure Mark Antony away from the Senate House while Caesar's assassination was taking place. Consequently, he was the only conspirator that did not stab Caesar.

As witnessed by Trebonius, Mark Antony "fled to his house amazed" in response to Julius Caesar's death. This indicates the strong relationship between the two Romans, and foreshadows the ardent vengeance that Antony is to develop.

Furthermore, Trebonius recalls that "Men, wives, and children stare, cry out, and run, as it were doomsday." The comparison between the assassination and Armageddon reinforce the idea that the conspirators were not acting in the interests of the general public, but instead in the interests of themselves and their own envy.