Given the high prevalence of such sounds in everyday life, having misophonia can have large negative effects on one's functioning in personal, academic, and work environments.

Although there are many idiosyncrasies in what may trigger a person with misophonia, the most common triggers are created by other humans, such as the sound of someone chewing, clearing their throat, tapping their foot, or typing on a keyboard.

Misophonia is a psychological disorder that is characterized by severe aversive responses to specific environmental sounds (i.e., triggers).

This indicates that misophonia is not a purely auditory processing disorder but is also influenced by a top-down process of source identification.

an fMRI study found that people with misophonia show increased response in the anterior insular cortex (AIC) in response to misophonic sounds, compared to control participants and other unpleasant or neutral sounds (Kumar et al., 2017).

Both the subjective judgment of aversiveness and the physiological measure of skin conductance response (SCR) increase when people with misophonia are presented with triggers (Edelstein et al., 2013).

The disorder is not yet recognized by the Diagnostic and Statistical Manual − 5th version (DSM-5; American Psychiatric Association, 2013), but there has been an increasing amount of research on the characterization and treatment of misophonia (Vitoratou et al., 2021; see also Brout et al., 2018, for a review).

For people who suffer from it, mouth sounds are common triggers. "Chewing is almost universal. Gum chewing is almost universal. They also don't like the sound of throat clearing. Coughing, sniffing, nose blowing — a number of things," says Jaelline Jaffe, a psychotherapist in Los Angeles who specializes in misophonia and works with Rapp.

isophonia is characterized by intense emotion like rage or fear in response to highly specific sounds, particularly ordinary sounds that other people make. The cause is unknown.