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- Nov 2022
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www.biorxiv.org www.biorxiv.org
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The genomes were uniformly of high completeness (Figure S2). Due to the high intrinsic base quality of HiFi reads (Q30 to Q40; from one error in 1000 to one error in 10,000) we were able to distinguish insertions of Wolbachia DNA into the host genome from true components of the Wolbachia genome, and to independently assemble even closely related strains with confidence
This whole study is really interesting. This is one part that is not entirely clear to me. How do you use this information to distinguish actual Wolbachia DNA from Wolbachia from insertions of Wolbachia DNA into the host genome?
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