The danger with this situation, according to Fromm, is that when an entire society is suffering from feelings of isolation and disconnection with the natural order (from nature itself, in Fromm’s view), the members of that society may seek connection with a societal structure that destroys their freedom and, thus, integrates their self into the whole (albeit in a dysfunctional way).
Reading this passage reminded me of 2020 and the beginning stages of the outbreak of covid when it was recommended to quarantine.