Futher reading
maybe add:
https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(24)00028-3
https://www.sciencedirect.com/science/article/pii/S0753332225006468
14 Matching Annotations
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019e8db0-3170-049a-5425-c5ec91f35d55.share.connect.posit.cloud 019e8db0-3170-049a-5425-c5ec91f35d55.share.connect.posit.cloud
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There are two relevant publications
it might be worth including, but might be too far off the path, that publication kinda explains the path that we took with the CD4 specific mouse
severin et al 2016 https://academic.oup.com/brain/article/139/6/1747/1754080?login=true
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Q2: According to reference 9, we claim that mir-128 over-expression supresses motor neuron activity. That is vague. Go to ref 9 and find what happens during ectopic brain expression
see previous comment. I will work on the manuscript later today, so there is an updated version of it available
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From reading the paper you should be able to answer: TipQ1: What prior work shows mir-128 is e
the references are not accessible through that google doc. let me know if that had something to do with my comments and running it through my office
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Mir-128b
maybe just write miR-128
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KHSV
and EBV ;)
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remeynelaing
typo remyelinating
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chalanges
typo challenges
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for
MS
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demyelnating
typo demyelinating
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RNA from m
and reversly transcribed cDNA
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extracellular vesicles (EVs)
we are not really isolating them (I mean it would be ideal but might be beyond the scope of this internship unless you disagree, I am happy to work on that) but I think it is ok to write that here.
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mir-128b
miR-128-3p
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called miR-128b,
we are detecting miR-128-3p
miR-128b is one of the 5p versions that is also expressed in the brain (there are 2 pre-miR-128s that are in different gene locations, I will specifcy those in the paper, but for Jaley that is probably not required. Processing of both pre-miRs leads to miR-128-3p, but there are 2 different miR-128-5p (a and b)
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