29 Matching Annotations
  1. Mar 2025
    1. These steps of synaptic transmission from synthesis to the eventual termination of the neurotransmitter comprise synaptic transmission.

      Having a healthy synapse is important for learning and memory, sensory perception and brain function.

    2. A very small space called a synapse or synaptic gap/cleft exists between the pre-synaptic axon's terminal and the post-synaptic neuron's dendritic spine.

      A synapse is made up of presynaptic and postsynaptic terminals. The post synaptic neuron integrates all the signals it gets and tells what to do.

    1. There are an enormous number of neurons in the human brain, but the number of possible different combinations of synaptic connections among those 80-100 billion neurons is unimaginable--one neuroscientist estimated that the number of possible patterns of interconnect between neurons in a human brain exceeds the number of atoms in the entire universe

      This is a reason why the brain has wrinkles and folds to fit as many neurons as possible.

    1. Nodes contain voltage-gated potassium (K+) and sodium (Na+) channels.

      During depolarization the sodium channels are open and during repolarization the potassium channels are open.

    2. The second main part of the neuron are the dendrites

      That is very interesting that dendrites have have different parts of them that have different functions thats i did not know about. The receptor sites receive molecules of neurotransmitter. Dendritic spines are part of the connections between neurons.

  2. Feb 2025
    1. Several of these endocrine glands are also discussed in greater detail as they relate to other topics in separate chapters.

      This is very interesting that the endocrine system has many different glands that produce different hormones and each hormone has a specific job.

    1. The PNS is divided into two major systems, called the autonomic nervous system and the somatic nervous system. Both systems of the PNS interact with the CNS and include sensory and motor neurons, but they use different circuits of nerves and ganglia.

      When talking about the PNS it was very easy to remember the two major systems. Somatic was things that you can tell your body too like for example grab water and autonomic is when the body monitors itself like when it gets hot we don't tell our body to sweat it automatically does that.

    1. The brain contains an estimated 86 billion neurons (Lent et al., 2012), and each neuron has thousands of synaptic connections to other neurons.

      The brain has a lot of neurons around 86 billion! As you can see the brain has many folds and these folds are called the gyrus. The reasoning behind the gyrus is because these folds give the brain more surface area to fit more neurons in the skull and also enable higher functions.

    1. The telecephalon will become the cerebrum. The diencephalon gives rise to several adult structures; two that will be important are the thalamus and the hypothalamus.

      The telencephalon is the largest portion of the brain in which this portions main function is speech and language. The diencephalon function is to release hormones and is also a processing center for sensory information and autonomic control.

    1. The meninges also contain cushioning cerebrospinal fluid (CSF).

      The csf is a protective measure for the brain that is able to absorb shock. Every day the human body produces about 500ml of csf a day.

    1. Neurons are responsible for the electrical signals that communicate information about sensations, produce movements in response to those stimuli, and induce thought processes within the brain.

      Neurons are a very complicated and interesting part of our body's. One thing about neurons that sticks with me the most is action potential which I learned heavily in my physiology class. Action potential is basically a quick electrical pulse that happens when a neuron sends a signal.

    1. Thus, understanding the structure of the nucleosome is key to understanding the precise and stable control of gene expression and regulation, providing a molecular interface between genes and environmentally induced changes in cellular activity.

      Being able to figure out what the epigenome does and how it works will be able to tell us how the different cells work but also how our environment can change our genes.

    2. A similar study examining newborns showed that methylation of the glucocorticoid receptor gene promoter maybe an early epigenetic marker of maternal mood and risk of increased hormonal responses to stress in infants 3 months of age

      This is a very interesting study that shows giving a newborn the physical touch it needs may improve better moods and less stress.

    1. The difficulties with finding clear-cut solutions to nature–nurture problems bring us back to the other great questions about our relationship with the natural world: the mind-body problem and free will.

      The nature vs nurture will be a forever debate but I think that both genetics and environment play a significant role in how person turns out to be.

    2. The message is clear: You can’t leave genes out of the equation. But keep in mind, no behavioral traits are completely inherited, so you can’t leave the environment out altogether, either.

      I believe that physically genetics explains the most but behavioral traits I believe mostly come from someone's environment.

    1. In individualistic cultures, such as the United States, status is heavily determined by individual accomplishments.

      I have noticed that living in the United States people view status through individual accomplishments rather than contributing to a group.

    2. In response to problems in our environment, we adapt both physically and psychologically to ensure our survival and reproduction.

      It is quite surprising how much humans have adapted to the world over time from finding a way to create fire to now have self driving cars.

    1. In short, there are differences in the time for processing auditory sounds in children with ASD compared to those without ASD.

      This is a very interesting fact to know. I did not know that using an EEG and MEG can see different processing times in children with ASD and children without ASD.

    1. The patient must be enclosed in a metal tube-like device for the duration of the scan, sometimes as long as thirty minutes, which can be uncomfortable and impractical for ill patients.

      The MRI is such a powerful machine but there are some flaws to it. You are in a loud and confined tube for multiple minutes. This may be great for patients that are able to do this but must be difficult to have a child or someone in general that does not feel comfortable doing the scan.

    1. They may ask “When does this activity occur?” Or “Where does this activity occur?” Some techniques are better for answering one of these questions, whereas other techniques are better for answering the other question.

      There are two questions being asked in this sentence. Since there are two questions and different techniques, which are the best techniques to answer these questions?

    1. Early philosophers

      For many of years people had different beliefs of where the mind was many believing it was the heart. Until one of the first people to say it was in the brain was Hippocrates. As time went on we were able to prove that this is where the mind resides.

    2. Today, these instruments have greatly contributed to our understanding of the brain and its function in behavior and cognition.

      Being able to use brain imaging has been such an important part of helping people out. In the medical field having the ability to take a picture of your brain and help diagnose any problems that they're might be is great. It is great way to help understand how the brain functions normally compared to when a brain does not function correctly.

    1. Gage's case is considered to be one of the first examples of scientific evidence indicating that damage to the frontal lobes may alter personality, emotions, and social interaction.

      I have heard of this famous story about Gage. It is crazy to think that damage to his frontal lobe caused him to change his personality and yet years later he became his old self. The way the body heals itself is crazy because I believe it is hard to explain how someone's mind became so angry after a horrific accident and yet years later he goes back to being calm.

    1. The more neuroscientific research progresses, the more clearly it is established that human behavior and mental processes—the key interests for psychological study—are intimately intertwined with activity in the brain.

      It is truly amazing how complicated and mysterious the brain is. There have been many divisions of psychobiology that have been discovered throughout time to help us understand the brain. The more advanced people and technology become the more I believe that there will be more divisions made.

    1. The modern scientific view of the world assumes that there are at least two fundamental properties of the universe.

      I am extremely confused on this whole concept in section 1.1.5. I was wondering if anyone had a website link or video explaining this more clearly?

    2. In other words, where damage occurs determines what functions are impacted and more damage has more of an effect. This reflects a key organizational principle of the brain: the localization of function.

      I understand that there are certain areas of the brain that are effected differently when damaged. When there is damage to the brain can the brain be healed back to normal or is the damage irreversible?