Publication update: peer-reviewed version now available

This preprint represents an earlier version of a study that was subsequently expanded and revised, and has now been published as:

Tei, S., Bando, M., Sakata, T. et al. Cohesin acts as a transcriptional gatekeeper by restraining pause–release to promote processive elongation. Nature Communications 17, 8487 (2026). https://doi.org/10.1038/s41467-026-76738-3

An expanded version of the study was also posted as a later preprint: https://doi.org/10.1101/2025.09.30.679672

Although the two preprints have different titles and DOIs, they represent earlier and later stages of the same study. Readers are encouraged to consult the peer-reviewed article for the final results and conclusions, and to cite the published version where appropriate.

Katsuhiko Shirahige & Shoin Tei Corresponding authors