5,106 Matching Annotations
- Mar 2021
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europepmc.org europepmc.org
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Initial studies
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cellular circuits
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information
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phenomena
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stochastic
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stochastic
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regulatory molecules
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each single cell
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GTEx
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TCGA
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FANTOM
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ENCODE
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consortia
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single-cell RNA-seq experiment
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cells
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observations
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Single-cell data
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genetic perturbations
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regulation
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cellular phenotypes
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regulators
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expression
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gene regulation
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biologists
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decades
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tissue matrix
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cells
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cells
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cells
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responses
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differentiation
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cell type
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states
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molecular mechanisms
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Human Cell Atlas
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intracellular
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inter-cellular circuits
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Molecular mechanisms
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clinical information
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tumor
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bulk
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deconvolute
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signatures
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clinical phenotypes
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patients
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mouse model
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human tumors
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regulatory program
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exhausted state
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exhaustion
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activation
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T-cells
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functional states
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non-malignant cells
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low-grade glioma
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stem-like cells
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quiescent cells
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proliferating
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drug-resistant states
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cancer stem cells
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cell states
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malignant cells
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endothelial cells
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stromal
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immune
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malignant
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fresh tumors
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single-cell RNA-seq
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myeloproliferative neoplasms
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low-grade glioma
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glioblastoma
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melanoma
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mutations
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acute myeloid leukemia
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acute lymphoblastic leukemia
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breast cancer
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evolution of tumors
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clonal structure
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single-cell genome analysis
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colon cancer
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heterogeneity
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radioresistance
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cancer stem cells
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Early studies
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single-cell qPCR
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short term
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cancer
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recurrence
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pediatric Acute Lymphoblastic Leukemia,
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B cell development
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trajectory analysis
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VDJ recombination
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rare population
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normal setting
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discovered
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disease
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rare immune populations
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identification
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signature
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disease
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identify the corresponding population
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healthy cells
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cell-surface markers
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classification
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Acute Myeloid Leukemia
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hematopoietic stem and progenitor cells (HSPCs)
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classification
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healthy
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hematopoietic cells
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single-cell mass cytometry
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cell-signaling assays
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hematopoietic system
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gene transcription
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regulation
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genetic variation
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single-cell analysis
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blood samples
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bulk-tissue
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deconvolute cellular proportions
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states
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cell types
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Future studies
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studies
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studies
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studies
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studies
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studies
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treatment response
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disease course
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genome variants
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variation
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states
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cell proportions
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patients
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patients
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patients
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patient
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patients
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patients
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patients
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patients
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Single-cell information
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cell
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physiological behaviors
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challenge
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immune system
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informative
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cellular circuitry
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disease
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cellular physiology
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disease samples
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Single-cell analysis
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tumor microenvironment
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malignant cells
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disease processes
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ecosystem
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tissue
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cells
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abnormal cells
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interactions
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understanding
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interest
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cell populations
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markers
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molecular signatures
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tissues
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cells
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FACS analysis
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histopathological
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decades
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disease
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single-cell analysis
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proportions
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ecosystems
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interactions
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cellular functions
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disease
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Disease
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cellular ecosystems
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cells
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Human Cell Atlas
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mouse Th17 cells
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pathogenicity
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mouse immune dendritic cells
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lipopolysaccharide (LPS)
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CC BY 4.0
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mouse hematopoietic stem and progenitor cells
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dynamic processes
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PCA
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gene signatures
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RNA profile
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embedded in low-dimensional space
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dots
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single cells
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cells
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paracrine signaling
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interferon beta
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module of genes
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cells
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'precocious' cells
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