Aspergillus, section Fumigati species are the most common ones isolated, followed by those from sections Flavi and Nigri. So-called cryptic species are relatively common causes of invasive disease.

Yamamuro R, Kimura M, Asano-Mori Y, et al. Clinical and Microbiological Characteristics of Proven Invasive Aspergillosis Due to Rare/Cryptic Species in Allogeneic Hematopoietic Stem Cell Transplant Recipients. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0163021. doi: 10.1128/AAC.01630-21. Epub 2021 Nov 15. PMID: 34780271; PMCID: PMC8765323.

Voriconazole and isavuconazole are currently the recommended first line agents in the 2017 ESCMID-ECMM-ERS guidelines:

Ullmann AJ, Aguado JM, Arikan-Akdagli S, et al. Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline. Clin Microbiol Infect. 2018 May;24 Suppl 1:e1-e38. doi: 10.1016/j.cmi.2018.01.002. Epub 2018 Mar 12. PMID: 29544767.

The EORTC/MSG-ERC definitions have recently been revised:

Donnelly JP, Chen SC, Kauffman CA, et al. Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. Clin Infect Dis. 2020 Sep 12;71(6):1367-1376. doi: 10.1093/cid/ciz1008. PMID: 31802125; PMCID: PMC7486838.

More than 400 species are currently described.

Dagenais TR, Keller NP. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin Microbiol Rev. 2009 Jul;22(3):447-65. doi: 10.1128/CMR.00055-08. PMID: 19597008; PMCID: PMC2708386.

Arastehfar A, Carvalho A, Houbraken J, et al. Aspergillus fumigatus and aspergillosis: From basics to clinics. Stud Mycol. 2021 May 10;100:100115. doi: 10.1016/j.simyco.2021.100115. PMID: 34035866; PMCID: PMC8131930.

It is essential that building works are carefully planned in advance and follow a specific infection control risk assessment policy.

Talento AF, Fitzgerald M, Redington B, O'Sullivan N, Fenelon L, Rogers TR. Prevention of healthcare-associated invasive aspergillosis during hospital construction/renovation works. J Hosp Infect. 2019 Sep;103(1):1-12.

Mareković I. What's New in Prevention of Invasive Fungal Diseases during Hospital Construction and Renovation Work: An Overview. J Fungi (Basel). 2023 Jan 23;9(2):151.

The incidence among lung transplants varies widely (8-23%).

Neofytos D, Garcia-Vidal C, Lamoth F, Lichtenstern C, Perrella A, Vehreschild JJ. Invasive aspergillosis in solid organ transplant patients: diagnosis, prophylaxis, treatment, and assessment of response. BMC Infect Dis 2021; 21(1): 296.

Some recent studies have found lower incidences (e.g. 8%) in allogeneic HSCT recipients.

Invasive Aspergillosis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients: A Large Cohort Single-Center Study. Yuliya A. Rogacheva, Vladislav V. Markelov, Marina O. Popova, et al. Blood. 2021; 138 (Suppl 1): doi.org/10.1182/blood-2021-153762.

The full sub-generic classification would be: subgenus Fumigati, section Fumigati, series Fumigati.

More than 400 species are currently described.

Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species. J. Houbraken, S. Kocsubé, C.M. Visagie, et al. Stud Mycol. 2020 Mar; 95: 5–169.

More than 400 species are currently described.

Voriconazole and isavuconazole are currently the recommended first line agents in the 2017 ESCMID-ECMM-ERS guidelines:

Ullmann AJ, Aguado JM, Arikan-Akdagli S, et al. Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline. Clin Microbiol Infect. 2018 May;24 Suppl 1:e1-e38. doi: 10.1016/j.cmi.2018.01.002. Epub 2018 Mar 12. PMID: 29544767.

The EORTC/MSG-ERC definitions have recently been revised:

Donnelly JP, Chen SC, Kauffman CA, et al. Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. Clin Infect Dis. 2020 Sep 12;71(6):1367-1376. doi: 10.1093/cid/ciz1008. PMID: 31802125; PMCID: PMC7486838.

Arastehfar A, Carvalho A, Houbraken J, et al. Aspergillus fumigatus and aspergillosis: From basics to clinics. Stud Mycol. 2021 May 10;100:100115. doi: 10.1016/j.simyco.2021.100115. PMID: 34035866; PMCID: PMC8131930.

Dagenais TR, Keller NP. Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin Microbiol Rev. 2009 Jul;22(3):447-65. doi: 10.1128/CMR.00055-08. PMID: 19597008; PMCID: PMC2708386.

It is essential that building works are carefully planned in advance and follow a specific infection control risk assessment policy.

Talento AF, Fitzgerald M, Redington B, O'Sullivan N, Fenelon L, Rogers TR. Prevention of healthcare-associated invasive aspergillosis during hospital construction/renovation works. J Hosp Infect. 2019 Sep;103(1):1-12.

Mareković I. What's New in Prevention of Invasive Fungal Diseases during Hospital Construction and Renovation Work: An Overview. J Fungi (Basel). 2023 Jan 23;9(2):151.

The incidence among lung transplants varies widely (8-23%).

Neofytos D, Garcia-Vidal C, Lamoth F, Lichtenstern C, Perrella A, Vehreschild JJ. Invasive aspergillosis in solid organ transplant patients: diagnosis, prophylaxis, treatment, and assessment of response. BMC Infect Dis 2021; 21(1): 296.

Some recent studies have found lower incidences (e.g. 8%) in allogeneic HSCT recipients.

Invasive Aspergillosis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients: A Large Cohort Single-Center Study. Yuliya A. Rogacheva, Vladislav V. Markelov, Marina O. Popova, et al. Blood. 2021; 138 (Suppl 1): doi.org/10.1182/blood-2021-153762.

More than 400 species are currently described.

Classification of Aspergillus, Penicillium, Talaromyces and related genera (Eurotiales): An overview of families, genera, subgenera, sections, series and species. J. Houbraken, S. Kocsubé, C.M. Visagie, et al. Stud Mycol. 2020 Mar; 95: 5–169.

Aspergillus, section Fumigati species are the most common ones isolated, followed by those from sections Flaviand Nigri. So-called cryptic species are relatively common causes of invasive disease.

Yamamuro R, Kimura M, Asano-Mori Y, et al. Clinical and Microbiological Characteristics of Proven Invasive Aspergillosis Due to Rare/Cryptic Species in Allogeneic Hematopoietic Stem Cell Transplant Recipients. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0163021. doi: 10.1128/AAC.01630-21. Epub 2021 Nov 15. PMID: 34780271; PMCID: PMC8765323.

The full sub-generic classification would be: subgenus Fumigati, section Fumigati, series Fumigati.