It is supposed probable that a building of somewhat more size in the middle of the grounds may be called for in time, in which may be rooms for religious worship under such impartial regulations as the visitors shall prescribe
I believe that this quote sets apart Jefferson from many of his colleagues regarding secularization and separation of church and state. If the University of Virginia is to be public and funded by the state, it is obligatory that it shall be unaffiliated with any religion. However, Jefferson still considers those who practice religion by calling for the construction of a building for religious practice. He does not ask for regulation of the practice of any particular religion, but he asks for ground rules for all religious communities to follow while using the chapel. I think that Jefferson handled this matter very maturely and righteously, as religious matters are always of debate. However, I am curious to know why he presumably chose to have this building built in the center of grounds.