Irritability, anger, isolation, and withdrawing oneself are all symptoms of depression. The speaker of the poem is familiar with the need for isolation and the feeling of being misunderstood.

"It is when you have left the tried and true, but have not yet been able to replace it with anything else. It is when you are finally out of the way. It is when you are between your old comfort zone and any possible new answer" - Richard Rohr

The context of the poem leads readers to believe that the subject is idling between comfort and discomfort

https://en.wikipedia.org/wiki/Liminality

The concept of liminality can lend some context to Drake's poem: it's the eerie-feeling threshold that lies between two destinations. In the context of the poem, it's the space between there the subject of the poem wants to be versus where they are. Liminality is uncomfortable, like one is acutely aware of their sense of time as they reside in the threshold between two spaces.

Liminal Spaces are the times between 'what was' and the 'next'. It's a place of transition and unknowing. Places like rest stops and diners late at night can be liminal spaces because they serve the purpose of being a 'midpoint' between two places or activities.

https://introvertdear.com/news/introverts-help-dont-fit-in/

The first line of the poem struck me as being a call out to the fellow introverts who are stuck in their comfort zones.

https://www.poetryfoundation.org/poems/44299/elegy-written-in-a-country-churchyard

The line "The paths of glory lead but to the grave." from Thomas Gray's poem also served to inspire the title of the 1917 painting by Christopher Nevinson, Paths of Glory.

(https://www.simplypsychology.org/maslow.html)

Maslow’s hierarchy of needs is a pyramid graphic that is used in motivational psychology to depict a five-tier model of human needs. Needs lower down in the hierarchy must be satisfied before one can tend to needs higher up, (Ex: one needs basic physiological needs like food and water before they can move to seek safety and security).

https://www.youtube.com/watch?v=_Yhyp-_hX2s

Any time I hear the phrase "Lose Yourself", it reminds me of this song by Eminem. In recent years, it became more of a meme, but I still find it to be relevant to the context of the poem

Because drug usage has already been alluded to in the poem, one can assume that the faces of these sex workers are 'pocked' due to drug usage and the detriments it has on the body.

Attached is one of those overdramatic videos of before/after pictures that showcase the damage that drugs can do to the skin/face:

https://www.youtube.com/watch?v=uU7aRJ4WpUw

The imagery in this line reminded me of the Grimm's fairytale version of Cinderella, in which the step-sisters have their eyes pecked out by birds as a result of the ways they had mistreated Cinderella. Maybe the imagery in this line is meant to evoke that the parents are suffering as a result of their son's actions. https://www.bustle.com/articles/61053-9-things-about-the-original-brothers-grimm-cinderella-story-that-are-nothing-like-the-disney-version