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  1. Feb 2024
  2. chem.libretexts.org chem.libretexts.org
    26.3: Amino Acids, the Henderson-Hasselbalch Equation, and Isoelectric Points
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    1. elliemj 27 Feb 2024
      The very high pH required to remove the last acidic proton from arginine reflects the exceptionally high basicity of the guanidine moiety at the end of the side chain.

      Moiety: part of a molecule - a substructure. Can include a functional group (so basically the R side chain). The amino acid side chain has a particularly high pH.

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    chem.libretexts.org/Bookshelves/Organic_Chemistry/Organic_Chemistry_(Morsch_et_al.)/26:_Biomolecules-_Amino_Acids_Peptides_and_Proteins/26.03:_Amino_Acids_the_Henderson-Hasselbalch_Equation_and_Isoelectric_Points