5 Matching Annotations
  1. Jun 2017
    1. (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5) are involved in the construction of the replication complex which is key to successful RNA replication

      These are coded in the polyprotein, a hallmark of flaviviruses, but also seen in Human Rhinovirus, as the polyprotein codes similrly for 11 proteins, some functioning as replication complex.

    2. single stranded RNA that is positively charged

      This extend beyond the flaviviruses and is also seen in Human Rhinovirus.

    1. translated protein gets cleaved by virally encoded proteases and then yields

      Coding for a single polyprotein is also common for flaviviruses like Human Rhinovirus, and then getting cleaved into proteins that assist in replication process.

    2. Positive sense, single-stranded-RNA (ssRNA) (8)

      This is also shared with the flaviviruses, which includes Human Rhinovirus.

  2. Apr 2017
    1. super-shedders,

      Super Shedders v Spreaders Nature article differentiates the two terms, super spreading more based on opportunity to spread disease, while shedding is more based on quantity of infectious units/organisms they may spread.