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    A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration
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    1. jcotell 09 Oct 2026
      is characterized by personality change, involuntary movements, and dementia typically beginning in midadulthood and progressing toward death ∼18 years from onset

      This gives a good timeline and symptoms for Huntingtons

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    sciencedirect.com/science/article/pii/S0896627300807643