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      Update of Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review. Valk SJ, Piechotta V, Chai KL, Doree C, Monsef I, Wood EM, Lamikanra A, Kimber C, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Cochrane Database Syst Rev. 2020 May 14;5(5):CD013600. doi: 10.1002/14651858.CD013600. Update in: Cochrane Database Syst Rev. 2020 Jul 10;7:CD013600. doi: 10.1002/14651858.CD013600.pub2. PMID: 32406927 Free PMC article. 189 2 189 0 Similar articles Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review. Chai KL, Valk SJ, Piechotta V, Kimber C, Monsef I, Doree C, Wood EM, Lamikanra AA, Roberts DJ, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Cochrane Database Syst Rev. 2020 Oct 12;10:CD013600. doi: 10.1002/14651858.CD013600.pub3. Update in: Cochrane Database Syst Rev. 2021 May 20;5:CD013600. doi: 10.1002/14651858.CD013600.pub4. PMID: 33044747 158 7 56 0 Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review. Piechotta V, Iannizzi C, Chai KL, Valk SJ, Kimber C, Dorando E, Monsef I, Wood EM, Lamikanra AA, Roberts DJ, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Cochrane Database Syst Rev. 2021 May 20;5(5):CD013600. doi: 10.1002/14651858.CD013600.pub4. Update in: Cochrane Database Syst Rev. 2023 Feb 1;2:CD013600. doi: 10.1002/14651858.CD013600.pub5. PMID: 34013969 Free PMC article. 193 4 81 0 Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review. Valk SJ, Piechotta V, Chai KL, Doree C, Monsef I, Wood EM, Lamikanra A, Kimber C, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Cochrane Database Syst Rev. 2020 May 14;5(5):CD013600. doi: 10.1002/14651858.CD013600. Update in: Cochrane Database Syst Rev. 2020 Jul 10;7:CD013600. doi: 10.1002/14651858.CD013600.pub2. PMID: 32406927 Free PMC article. 189 2 189 0 Vitamin D supplementation for the treatment of COVID-19: a living systematic review. Stroehlein JK, Wallqvist J, Iannizzi C, Mikolajewska A, Metzendorf MI, Benstoem C, Meybohm P, Becker M, Skoetz N, Stegemann M, Piechotta V. Cochrane Database Syst Rev. 2021 May 24;5(5):CD015043. doi: 10.1002/14651858.CD015043. PMID: 34029377 Free PMC article. 116 2 88 2 Remdesivir for the treatment of COVID-19. Ansems K, Grundeis F, Dahms K, Mikolajewska A, Thieme V, Piechotta V, Metzendorf MI, Stegemann M, Benstoem C, Fichtner F. Cochrane Database Syst Rev. 2021 Aug 5;8(8):CD014962. doi: 10.1002/14651858.CD014962. Update in: Cochrane Database Syst Rev. 2023 Jan 25;1:CD014962. doi: 10.1002/14651858.CD014962.pub2. PMID: 34350582 Free PMC article. 209 0 97 2

    1. This meta-analysis shows that cannabis smoking increased the risk of suicide attempt, suicidal ideation and suicide planning in young individuals of 11-21 years of age. The high risk of suicide behaviors could vary depending on the population studied; therefore, more studies are necessary to corroborate the risk of presenting suicide behaviors in individuals of 11-21 years of age who smoke cannabis.

      BIOmetaAnalysis

    1. There is considerable variation in the estimated effect size among included studies due to heterogeneity; hence, a random effect model was used for meta-analysis. The findings of our study suggest that the effect size of BDNF levels was 0.25 with 95% CI (-0.55; 1.05) in cannabis users, which was not statistically significant (p-value=0.54). Therefore, it is important to interpret the results with caution, and additional research is warranted to investigate the potential factors contributing to this heterogeneity.

      BIOmetaAnalysis

    1. Estos hallazgos resaltan la necesidad de incluir el consumo de cannabis como factor de riesgo en la planificación quirúrgica y los protocolos de atención al paciente, y se justifica la realización de más estudios.

      BIOmetaAnalysis

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