7,785 Matching Annotations
  1. Sep 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Evidence Map of Pancreatic Surgery - Living Systematic Review and Meta-Analysis
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    sciencedirect.com/science/article/abs/pii/S1424390320302805
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    1417P Mixed treatment comparisons evaluating contemporary therapies in metastatic castration sensitive prostate cancer (mCSPC): A living systematic review
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    sciencedirect.com/science/article/pii/S0923753422037541
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    The safety of digestive tract cancer surgery during COVID-19: A living systematic review and meta-analysis
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    sciencedirect.com/science/article/pii/S1015958423003263
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    A living systematic review on anti-HIV, anti-TB and anti-malarial drug unavailability and their impact on infection management
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    sciencedirect.com/science/article/pii/S1201971224005447
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    Morphological and tissue-based molecular characterization of oral lesions in patients with COVID-19: A living systematic review
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    pubmed.ncbi.nlm.nih.gov/35180550/
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    Endovascular thrombectomy for large ischemic strokes: An updated living systematic review and meta-analysis of randomized clinical trials
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    pubmed.ncbi.nlm.nih.gov/38640579/
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    Early goal-directed therapy for severe sepsis and septic shock: A living systematic review
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    sciencedirect.com/science/article/abs/pii/S0883944116301393
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    Toxicity Profile of Janus Kinase Inhibitors (JAKi) in Patients with Myelofibrosis: A Report from a Living Systematic Review and Meta-Analysis
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    CO4 The True Value of Living Systematic Reviews (LSRs): A Case Report Within Systemic Lupus Erythematosus (SLE)
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    Oral Health and Hygiene Status of Global Transgender Population: A Living Systematic Review and Meta-Analysis
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    Prospective and multicenter study to assess the safety and effectiveness of a physiotherapy treatment through self-myofascial release with Foam Roller in patients with hemophilic ankle arthropathy. A randomized clinical trial.
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    Short vs. long antibiotic treatment for pyelonephritis and complicated urinary tract infections: a living systematic review and meta-analysis of randomized controlled trials
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    Systemic treatment options for metastatic castration resistant prostate cancer: A living systematic review
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    Efficacy and Safety of Medical Interventions for Moderate to Severe Hidradenitis Suppurativa: A Living Systematic Review and Network Meta-Analysis
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    Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain
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    Prophylaxis against covid-19: living systematic review and network meta-analysis
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    Abstract 159: Transradial versus transfemoral access for endovascular thrombectomy: A Living Systematic Review and Updated Meta‐Analysis | Stroke: Vascular and Interventional Neurology
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    POS0514 Long-term use of glucocorticoids in people with rheumatoid arthritis: a Cochrane living systematic review
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    open-research-europe.ec.europa.eu/articles/4-202/v2
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    Comparative Effectiveness of Coronary CT Angiography and Standard of Care for Evaluating Acute Chest Pain: A Living Systematic Review and Meta-Analysis | Radiology: Cardiothoracic Imaging
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    Effectiveness of Conservative Interventions After Acute Hamstrings Injuries in Athletes: A Living Systematic Review
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    Systemic Immunomodulatory Treatments for Atopic Dermatitis: Update of a Living Systematic Review and Network Meta-analysis
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    Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Quarterly Progress Report: May 2021
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    Adjuvant Tyrosine Kinase Inhibitors in Renal Cell Carcinoma: A Concluded Living Systematic Review and Meta-Analysis
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    Apolipoprotein E4 Polymorphism and Outcomes from Traumatic Brain Injury: A Living Systematic Review and Meta-Analysis
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    Genetic Influences on Patient-Oriented Outcomes in Traumatic Brain Injury: A Living Systematic Review of Non-Apolipoprotein E Single-Nucleotide Polymorphisms
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    pubmed.ncbi.nlm.nih.gov/29799308/
  86. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Blood-Based Protein Biomarkers for the Management of Traumatic Brain Injuries in Adults Presenting to Emergency Departments with Mild Brain Injury: A Living Systematic Review and Meta-Analysis
    1
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    pubmed.ncbi.nlm.nih.gov/29020853/
  87. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adherence to Guidelines in Adult Patients with Traumatic Brain Injury: A Living Systematic Review
    1
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    pubmed.ncbi.nlm.nih.gov/26431625/
  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A New Approach to Evidence Synthesis in Traumatic Brain Injury: A Living Systematic Review
    1
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    pubmed.ncbi.nlm.nih.gov/26414062/
  89. link.springer.com link.springer.com
    Clinical testing of the cardiovascular effects of e-cigarette substitution for smoking: a living systematic review
    1
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    link.springer.com/article/10.1007/s11739-022-03161-z
  90. www.sciencedirect.com www.sciencedirect.com
    The association between influenza vaccination, cardiovascular mortality and hospitalization: A living systematic review and prospective meta-analysis
    1
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    sciencedirect.com/science/article/pii/S0264410X24000537
  91. www.bmj.com www.bmj.com
    Update to living systematic review on drug treatments for covid-19
    1
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    bmj.com/content/378/bmj.o1717
  92. www.bmj.com www.bmj.com
    Update to living systematic review on prediction models for diagnosis and prognosis of covid-19
    1
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    bmj.com/content/378/bmj.o2009
  93. www.bmj.com www.bmj.com
    Update to living systematic review
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    bmj.com/content/369/bmj.m2204
  94. www.bmj.com www.bmj.com
    Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal
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    bmj.com/content/369/bmj.m1328
  95. www.bmj.com www.bmj.com
    Update to living systematic review on effectiveness of heterologous and homologous covid-19 vaccine regimens
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    bmj.com/content/379/bmj.o2865
  96. www.bmj.com www.bmj.com
    Update to living systematic review on prophylaxis against covid-19
    1
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    bmj.com/content/380/bmj.p688
  97. www.bmj.com www.bmj.com
    Update to living systematic review on covid-19 in pregnancy
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    bmj.com/content/377/bmj.o1205
  98. www.bmj.com www.bmj.com
    Update to living systematic review on SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission
    1
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    bmj.com/content/384/bmj.p2929
  99. www.bmj.com www.bmj.com
    SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis
    1
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    bmj.com/content/376/bmj-2021-067696
  100. www.bmj.com www.bmj.com
    Medications for adults with type 2 diabetes: a living systematic review and network meta-analysis
    1
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    bmj.com/content/390/bmj-2024-083039
  101. f1000research.com f1000research.com
    Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barr&eacute; syndrome: From systematic review to living systematic review
    1
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    f1000research.com/articles/7-196
  102. www.sciencedirect.com www.sciencedirect.com
    Prevalence of spasticity following stroke and its impact on quality of life with emphasis on disability in activities of daily living. Systematic review
    1
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    sciencedirect.com/science/article/abs/pii/S0028384314603005
  103. www.bmj.com www.bmj.com
    Update to living systematic review on covid-19 in pregnancy
    1
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    bmj.com/content/372/bmj.n615
  104. Aug 2025
  105. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A living meta-ecological study of the consequences of the COVID-19 pandemic on mental health
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC7936586/
  106. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Psychological treatment of depression: A systematic overview of a 'Meta-Analytic Research Domain'
    1
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    pubmed.ncbi.nlm.nih.gov/37178828/
  107. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use
    2
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    pubmed.ncbi.nlm.nih.gov/39665378/
  108. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interventions for increasing fruit and vegetable consumption in children aged five years and under
    1
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    pubmed.ncbi.nlm.nih.gov/39312396/
  109. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Cannabis-based products for pediatric epilepsy: A systematic review
    1
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    pubmed.ncbi.nlm.nih.gov/30515765/
  110. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interventions for increasing fruit and vegetable consumption in children aged five years and under
    1
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    pubmed.ncbi.nlm.nih.gov/28945919/
  111. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Five decades of research on psychological treatments of depression: A historical and meta-analytic overview
    1
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    pubmed.ncbi.nlm.nih.gov/37971844/
  112. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Interventions to prevent or cease electronic cigarette use in children and adolescents
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    pubmed.ncbi.nlm.nih.gov/37965949/
  113. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Conservative and Surgical Modalities in the Management of Pediatric Parapneumonic Effusion and Empyema: A Living Systematic Review and Network Meta-Analysis
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    pubmed.ncbi.nlm.nih.gov/37463660/
  114. www.mdpi.com www.mdpi.com
    Haloarchaeal Carotenoids: Healthy Novel Compounds from Extreme Environments
    2
    1. lmichan 20 Aug 2025
      Besides, potential biotechnological uses of haloarchaeal pigments are poorly explored. This work summarises what it has been described so far about carotenoids from haloarchaea and their production at mid- and large-scale, paying special attention to the most recent findings on the potential uses of haloarchaeal pigments in biomedicine.

      Además, los posibles usos biotecnológicos de los pigmentos haloarqueales están poco explorados. Este trabajo resume lo descrito hasta la fecha sobre los carotenoides de las haloarqueas y su producción a mediana y gran escala, con especial atención a los hallazgos más recientes sobre los posibles usos de los pigmentos haloarqueales en biomedicina.

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    mdpi.com/1660-3397/17/9/524
  115. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Archaea and Their Potential Role in Human Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC145348/
  116. www.mdpi.com www.mdpi.com
    Bacterioruberin: Biosynthesis, Antioxidant Activity, and Therapeutic Applications in Cancer and Immune Pathologies
    1
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    mdpi.com/1660-3397/22/4/167
  117. europepmc.org europepmc.org
    In vitro dual (anticancer and antiviral) activity of the carotenoids produced by haloalkaliphilic archaeon Natrialba sp. M6.
    1
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    europepmc.org/article/MED/32249805
  118. europepmc.org europepmc.org
    Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine.
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    europepmc.org/article/MED/31906001
  119. europepmc.org europepmc.org
    Biotechnological potentials of halophilic microorganisms and their impact on mankind.
    1
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    europepmc.org/article/MED/35669848
  120. www.mdpi.com www.mdpi.com
    Biotechnological Potential of Extremophiles: Environmental Solutions, Challenges, and Advancements
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    mdpi.com/2079-7737/14/7/847
  121. www.mdpi.com www.mdpi.com
    Halocins and C50 Carotenoids from Haloarchaea: Potential Natural Tools against Cancer
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    mdpi.com/1660-3397/22/10/448
  122. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Carotenoids in Skin Photoaging: Unveiling Protective Effects, Molecular Insights, and Safety and Bioavailability Frontiers
    1
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    pubmed.ncbi.nlm.nih.gov/40427459/
  123. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Haloalkaliphilic Archaea as Sources of Carotenoids: Ecological Distribution, Biosynthesis and Therapeutic Applications
    1
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    pubmed.ncbi.nlm.nih.gov/40702599/
  124. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Extremophilic models for astrobiology: haloarchaeal survival strategies and pigments for remote sensing
    1
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    pubmed.ncbi.nlm.nih.gov/31463573/
  125. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Deciphering Pathways for Carotenogenesis in Haloarchaea
    1
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    pubmed.ncbi.nlm.nih.gov/32155882/
  126. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Haloferax mediterranei Cells as C50 Carotenoid Factories
    1
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    pubmed.ncbi.nlm.nih.gov/33578828/
  127. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Haloarchaea: A Promising Biosource for Carotenoid Production
    1
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    pubmed.ncbi.nlm.nih.gov/33783738/
  128. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Haloarchaea have a high genomic diversity for the biosynthesis of carotenoids of biotechnological interest
    1
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    pubmed.ncbi.nlm.nih.gov/34942349/
  129. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    More Than Pigments: The Potential of Astaxanthin and Bacterioruberin-Based Nanomedicines
    1
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    pubmed.ncbi.nlm.nih.gov/37514016/
  130. link.springer.com link.springer.com
    Microbial Bacterioruberin: A Comprehensive Review
    1
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    link.springer.com/article/10.1007/s12088-024-01312-8
  131. www.nature.com www.nature.com
    Structural proteomics of an archaeon
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    nature.com/articles/nsb1000_903
  132. www.microbiologyresearch.org www.microbiologyresearch.org
    Haloparvum sedimenti gen. nov., sp. nov., a member of the family Haloferacaceae
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    microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.001033
  133. www.microbiologyresearch.org www.microbiologyresearch.org
    Halostagnicola alkaliphila sp. nov., an alkaliphilic haloarchaeon from commercial rock salt
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    microbiologyresearch.org/content/journal/ijsem/10.1099/ijs.0.023119-0
  134. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The response of selected members of the archaea to the gram stain
    1
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    pubmed.ncbi.nlm.nih.gov/8885405/
  135. link.springer.com link.springer.com
    Compilation of Analytical Techniques for Discrimination of Halophilic Archaea and Bacteria
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    link.springer.com/article/10.1134/S1062359022130167
  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microalgae, Seaweeds and Aquatic Bacteria, Archaea, and Yeasts: Sources of Carotenoids with Potential Antioxidant and Anti-Inflammatory Health-Promoting Actions in the Sustainability Era
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC10303815/
  137. academic.oup.com academic.oup.com
    Carotenoids produced by halophilic bacterial strains on mural paintings and laboratory conditions
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    academic.oup.com/femsle/article-abstract/366/21/fnz243/5645233
  138. link.springer.com link.springer.com
    Pigments of Halophilic Microorganisms
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    link.springer.com/chapter/10.1007/0-306-48053-0_6
  139. link.springer.com link.springer.com
    Antioxidant potential of pigments produced by halophilic archaea isolated from salt pans of India
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    link.springer.com/article/10.1007/s42398-024-00313-z
  140. www.frontiersin.org www.frontiersin.org
    Probing archaeal cell biology: exploring the use of dyes in the imaging of Sulfolobus cells
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    frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1233032/full
  141. www.microbiologyresearch.org www.microbiologyresearch.org
    Halobium palmae gen. nov., sp. nov., an extremely halophilic archaeon isolated from a solar saltern
    2
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    microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.001267
  142. www.nature.com www.nature.com
    Novel haloarchaeon Natrinema thermophila having the highest growth temperature among haloarchaea with a large genome size
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    nature.com/articles/s41598-018-25887-7
  143. www.microbiologyresearch.org www.microbiologyresearch.org
    International Journal of Systematic and Evolutionary Microbiology
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    microbiologyresearch.org/content/journal/ijsem
  144. journals.asm.org journals.asm.org
    The Mode of Cell Wall Growth in Selected Archaea Is Similar to the General Mode of Cell Wall Growth in Bacteria as Revealed by Fluorescent Dye Analysis | Applied and Environmental Microbiology
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    journals.asm.org/doi/10.1128/AEM.02423-10
  145. www.sciencedirect.com www.sciencedirect.com
    Extreme halophilic Archaea: Halobacterium salinarum carotenoids characterization and antioxidant properties
    2
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    sciencedirect.com/science/article/pii/S2405844024128630
  146. www.frontiersin.org www.frontiersin.org
    Bioactive molecules from haloarchaea: Scope and prospects for industrial and therapeutic applications
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    frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2023.1113540/full
  147. link.springer.com link.springer.com
    Characterization and biological activities of carotenoids produced by three haloarchaeal strains isolated from Algerian salt lakes
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    link.springer.com/article/10.1007/s00203-021-02611-0
  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Asgard archaea: Diversity, function, and evolutionary implications in a range of microbiomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC6646929/
  149. www.nature.com www.nature.com
    Occurrence of viable, red-pigmented haloarchaea in the plumage of captive flamingoes
    1
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    nature.com/articles/srep16425
  150. www.sciencedirect.com www.sciencedirect.com
    Pink discoloration due to pigmented Archaea on the walls of the so-called Michelangelo's “secret room” (Medici Chapel, Florence, Italy)
    1
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    sciencedirect.com/science/article/pii/S0048969725011313
  151. www.mdpi.com www.mdpi.com
    Archaea Carotenoids: Natural Pigments with Unexplored Innovative Potential
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    mdpi.com/1660-3397/20/8/524
  152. www.intechopen.com www.intechopen.com
    Haloarchaea May Contribute to the Colour of Avian Plumage in Marine Ecosystems
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    intechopen.com/chapters/75346
  153. pubs.rsc.org pubs.rsc.org
    Convergent evolution of animal and microbial rhodopsins
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    pubs.rsc.org/en/content/articlelanding/2023/ra/d2ra07073a
  154. www.sciencedirect.com www.sciencedirect.com
    Microbial bacterioruberin: The new C50 carotenoid player in food industries
    1
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    sciencedirect.com/science/article/abs/pii/S0740002024001618
  155. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The Antitumour Mechanisms of Carotenoids: A Comprehensive Review
    1
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    pubmed.ncbi.nlm.nih.gov/39334719/
  156. royalsocietypublishing.org royalsocietypublishing.org
    Halophilic archaea on Earth and in space: growth and survival under extreme conditions | Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
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    royalsocietypublishing.org/doi/10.1098/rsta.2014.0194
  157. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    The microbiology of red brines
    1
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    pubmed.ncbi.nlm.nih.gov/32948267/
  158. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Carotenoid Production by Halophilic Archaea Under Different Culture Conditions
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    pubmed.ncbi.nlm.nih.gov/26750123/
  159. www.mdpi.com www.mdpi.com
    Carotenoids from Haloarchaea and Their Potential in Biotechnology
    1
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    mdpi.com/1660-3397/13/9/5508
  160. www.mdpi.com www.mdpi.com
    Halophilic Carotenoids and Breast Cancer: From Salt Marshes to Biomedicine
    1
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    mdpi.com/1660-3397/19/11/594
  161. link.springer.com link.springer.com
    Photonic Potential of Haloarchaeal Pigment Bacteriorhodopsin for Future Electronics: A Review
    1
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    link.springer.com/article/10.1007/s00284-017-1271-5
  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Natural History of the Archaeal Domain
    1
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    onlinelibrary.wiley.com/doi/10.1002/9780470750865.ch2
  163. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Archaea
    1
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    onlinelibrary.wiley.com/doi/book/10.1002/9780470750865
  164. cshperspectives.cshlp.org cshperspectives.cshlp.org
    The Dispersed Archaeal Eukaryome and the Complex Archaeal Ancestor of Eukaryotes
    1
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    cshperspectives.cshlp.org/content/6/4/a016188
  165. www.nature.com www.nature.com
    The origin of eukaryotes and their relationship with the Archaea: are we at a phylogenomic impasse?
    1
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    nature.com/articles/nrmicro2426
  166. www.sciencedirect.com www.sciencedirect.com
    Phylogeny and evolution of the Archaea: one hundred genomes later
    1
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    sciencedirect.com/science/article/abs/pii/S1369527411000634
  167. link.springer.com link.springer.com
    The Archaeal Concept and the World it Lives in: A Retrospective
    1
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    link.springer.com/article/10.1023/B:PRES.0000030445.04503.e6
  168. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Archaea: an Invitation to Evolution†
    1
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    onlinelibrary.wiley.com/doi/abs/10.1128/9781555815516.ch1
  169. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Birth of the Archaea: A Personal Retrospective
    1
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    onlinelibrary.wiley.com/doi/abs/10.1002/9780470750865.ch1
  170. europepmc.org europepmc.org
    Salty secrets of Halobacterium salinarum AD88: a new archaeal ecotype isolated from Cuatro Cienegas Basin.
    10
    2. lmichan 07 Aug 2025
      Meanwhile, the deeper evolutionary divergences observed with other species points to the long-term evolutionary isolation and specialization of lineages that have adapted to distinct ecological niches, like Haloarcula, Halococcoides and Halodesulfurarcheum genera. From a broader haloarchaeal evolution perspective, the clear separation of Halobacterium from other genera (like Haloferax, Haloarcula,) reinforces that haloarchaea have diversified into multiple lineages that, despite sharing extreme halophily, have long independent evolutionary histories​. Such insights can inform how haloarchaeal species may have radiated into different ecological niches, since some clusters consist of strains isolated from similar habitats (salt mines, salterns, etc.), indicating that geographic or environmental factors played a role in their divergence [100].

      radiación

    3. lmichan 07 Aug 2025
      The close genetic relationships within Halobacterium clade suggest that recent evolutionary pressures have maintained high genetic similarity, likely due to similar environmental conditions and adaptive strategies. We propose that their evolutionary adaptations have been driven more by microenvironmental pressures not involving large-scale genetic changes within a relatively recent evolutionary timeframe, which might explain their close phylogenetic clustering. This highlights the importance of integrating phylogenetic, genomic, and ecological data to better understand microevolution in halophilic organisms.

      evolution

    4. lmichan 06 Aug 2025
      We hypothesize that Halobacterium salinarum AD88, isolated from CCB, has acquired genetic adaptations absent in previously studied strains, given the distinct ecological pressures present in the Cuatro Cienegas Basin (CCB) and limited number of cultured H. salinarum strains

      hipótesis

    5. lmichan 06 Aug 2025
      Recent studies have shown that a particular site at CCB harbors an extensive archaeal diversity. This site, named Archaean Domes (AD) given the microbial mats that form dome-like structures under wet conditions, is particularly rich in members of the Euryarchaeota phylum, which includes halophiles and methanogens, showing a relative abundance of approximately 14% over seven years

      uf

    6. lmichan 06 Aug 2025
      Overall, the genome of Halobacterium salinarum is highly dynamic and polyploid, typically possessing between 10 and 30 copies of its genome per cell [14, 15]. With an average genome size of ~2.0 Mbp and high G+C content (60%) [2, 16], Halobacterium sp. NRC-1, generally holds two 191 and 365 kbp-containing mega-plasmids, pNRC100 and pNRC200, respectively, which encode several genes essential for the organism’s survival in saline environments

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    9. lmichan 06 Aug 2025
      Its sophisticated mechanisms for ion regulation, osmoregulation, and phototrophic growth exemplify versatility for stress resistance and energy acquisition

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    Strategies of adaptation of microorganisms of the three domains of life to high salt concentrations
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    Surviving salt fluctuations: stress and recovery in Halobacterium salinarum, an extreme halophilic Archaeon
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