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  1. Jun 2020
    1. Gi disordersGut microbial imbalance has also been linked to many GI tract disorders. IBS is associated with alterations in the gut microbiota82 and is often comorbid with anxiety disorders.60,

      As i know that gut microbial imbalance has caused gallstone.

    2. As such, the microbiota profile may be a good representation of the environmental history of the individual

      That is interesting. Before this research, we always know that genetic,age, sex and diet are representation of individual profile. Now we also know that the microbiota profile is a good representation of history of the individual. I think it is a breakthrough in health care field contributing an important role to treat some certain diseases of human being.

    3. Bidirectional communication between the brain and the gut has been recognized with studies in the early 19th and 20th century showing that emotional state can alter the function of the gastrointestinal (GI) tract.1–3 One of the best examples is the work of Beaumont, an army surgeon, who was able to monitor gastric secretions through a fistula in a patient’s stomach and noted an association between mood and gut function.1Early postnatal life in mammals represents a period of bacteria colonization. Normal microbiota, also referred to as commensal microbiota, colonize the mammalian gut shortly after birth and remain there throughout life. In humans, the lower intestine contains 1014–1015 bacteria, that is, there are 10–100 times more bacteria in the gut than eukaryotic cells in the human body (1013).4–6 The interactions between commensal microbiota and its host are for the most part beneficial, and the presence of commensal organisms is critical to immune function, nutrient processing, other aspects of host physiology, and to brain development and function.7–

      The gastrointestinal tract influences very much to human emotional state. When we are sick or anxiety, we do not enjoy or feel tasty of the food. The more healthier , the more we enjoy the food and the more we are happier.

    4. At a basic level, the gut microbiota interacts with the human host in a mutualistic relationship – the host intestine pro-vides the bacteria with an environment to grow and the bacterium aids in governing homeostasis within the host. Therefore, it is reasonable to think that the lack of healthy gut microbiota may also lead to a deterioration of these relationships and ultimately disease. Indeed, a dysfunction in the gut–brain axis has been elucidated by a multitude of studies linked to neuropsychologi-cal, metabolic, and gastrointestinal disorders.

      Interesting. healthy gut microbiota is not only contributes its part to human's healthy but also brings happiness

    5. It has long been understood that healthy microbiota play a critical role in human development, particularly in areas such as immune development and metabolism.8 Although in its early stages, the emerging field of human microbiome research has indicated that gut microbiota may also play an important role in influencing brain development, behavior, and mood in humans.46,47 In a recent study, healthy female volunteers consumed a fermented milk product with a mix-ture of probiotics, including Bifidobacterium animalis subsp. Lactis, Streptococcus thermophilus, Lactobacillus bulga-ricus, and Lactococcus lactis subsp. Lactis, for 4 weeks. Results showed that probiotic consumption influenced brain activity in emotional centers in healthy individuals

      In my opinion, not only genetic but nutrition plays a very important role in human development, especially in areas such as immune and metabolism systems. It is also to support to treat some diseases. So i suggest we should eat yoghurt and drink milk everyday.