Great paper, congratulations!

I may be misunderstanding, but in the MPC definition:

“m_i is the number of ‘benign’ missense variants … with a fitted probability of pathogenicity value that is less than the fitted value for variant i”

Should this be “greater than” rather than “less than”?

As written, using “less than” would seem to assign lower MPC scores to more severe variants, whereas the definition of d_i =−log10(m_i/M) implies the opposite (i.e. high MPC for variants more extreme than most benign variants).

Just wanted to check if I’m interpreting this correctly.