8 Matching Annotations
  1. Jun 2025
  2. Apr 2025
    1. Transporter mutations can result in a clinical syndrome of mental retardation, myopathy, and low serum T4 levels (Allan-Herndon-Dudley syndrome)

      low T4, high T3

      brain mainly use T3

    2. Transporter mutations can result in a clinical syndrome of mental retardation, myopathy, and low serum T4 levels (Allan-Herndon-Dudley syndrome)

      low T4, high T3 brain mainly use T3

    1. autosomal dominant polycystic kidney disease

      polycystic kidney disease: * autosomal dominant: round cysts, adult, 90% * autosomal recessive: tubular cysts, baby, 10%

    2. Sustained nonpulsatile administration of GnRH or GnRH analogs inhibits the release of FSH and LH by the pituitary in both women and men, resulting in hypogonadotropic hypogonadism

      why is it considered "hypogonadotrophic"?