Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) cause familialParkinson’s disease, and sequence variations are associated with the sporadic form of the disease.LRRK2 phosphorylates a subset of RAB proteins implicated in secretory and recycling traffickingpathways, including RAB8A and RAB10. Another RAB protein, RAB29, has been reported to recruitLRRK2 to the Golgi,