- Jun 2017
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sites.google.com sites.google.com
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human-human contact
Ebola is transmitted by direct contact, but MMR includes indirect contact by air.
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sites.google.com sites.google.com
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spreads through the air
MMR can spread indirectly by air, but Ebola does not.
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synthesize a positive-strand antigenome,
Both MMR and Ebola synthesize a positive-strand antigenome.
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97% effective vaccine MMR
MMR has a vaccine available, but not Ebola.
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- May 2017
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www.researchgate.net www.researchgate.net
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Growth will be visible after48 hr. Heavily restreak the growth onto a newMH agar plate and incubate for another 24 to36 hr.
Time for growth.
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Multiple types of media can be used to cultivate it; however, Mueller Hinton broth and agar support the best C. jejuni growth. Optimum atmosphere for C. jejuni is 85% N2, 10% CO2, and 5% O2.
Lab conditions.
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emedicine.medscape.com emedicine.medscape.com
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Pathophysiology
Virulence Factors
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Drug-resistant Klebsiella
Antibiotic resistance
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www.microbiologyinpictures.com www.microbiologyinpictures.com
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Tests for identification of Klebsiella pneumoniae
Lab tests
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It is also an opportunistic pathogen for patients with chronic pulmonary disease, enteric pathogenicity, nasal mucosa atrophy, and rhinoscleroma.
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Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose fermenting, facultative anaerobic, rod shaped bacterium found in the normal flora of the intestines
Gram stain
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virology-online.com virology-online.com
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C. Pathogenesis
Pathogenesis of RSV
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis
Chain of infection of RSV
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Given the asymptomatic nature of lower genital tract gonococcal infection, nearly one in five women who do not receive treatment will develop pelvic inflammatory disease
sequelae
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cmr.asm.org cmr.asm.org
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Given the global nature of gonorrhea, the high rate of usage of antimicrobials, suboptimal control and monitoring of antimicrobial resistance (AMR) and treatment failures, slow update of treatment guidelines in most geographical settings, and the extraordinary capacity of the gonococci to develop and retain AMR, it is likely that the global problem of gonococcal AMR will worsen in the foreseeable future and that the severe complications of gonorrhea will emerge as a silent epidemic.
Public health concerns
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Adult group C beta-hemolytic streptococcal pharyngitis has a prevalence of approximately 5%.
Case report
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jcm.asm.org jcm.asm.org
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All isolates were susceptible to penicillin, and their MICs ranged from ≤0.016 to 0.06 μg/ml. The MBCs ranged between ≤0.016 and 0.5 μg/ml, with no evidence of tolerance. Three isolates, two GGS (large-colony phenotype) and one GCS (large-colony phenotype), were resistant to erythromycin (MICs > 16 μg/ml). The range of erythromycin MICs was ≤0.016 to >16 μg/ml. All isolates were susceptible to vancomycin (MICs between 0.12 and 0.5 μg/ml). Eighteen isolates of GGS exhibited tolerance of vancomycin (MBCs 32 or more times higher than the MICs [Table 2]).
Antibiotic resistance
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- Apr 2017
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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t also has a unique mode of action inhibiting the second stage of cell wall synthesis of susceptible bacteria. There is also evidence that vancomycin alters the permeability of the cell membrane and selectively inhibits ribonucleic acid synthesis.
mechanism of action of vancomycin antibiotic
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jcm.asm.org jcm.asm.org
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Briefly, the organism was plated on blood Mueller-Hinton agar and incubated at 35°C in ambient air (preferred), or with CO2 if required for growth, for 20 to 24 h.
Culture growth requirements
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All 50 strains were susceptible to vancomycin
effective antibiotic
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based on alpha-hemolysis, gram-positive reaction, coccus morphology in chains, negative catalase test, and exclusions of pneumococci and enterococci by routine biochemical tests (optochin test, bile solubility, and PYR [N,N-dimethylaminocinnamaldehyde] test).
Identification of VGS in lab
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nutritionally fastidious and mainly alpha-hemolytic on sheep blood agar
Lab media
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Sequencing analysis of the 16S rRNA gene has become an essential part of bacterial taxonomy
Additional lab tests
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www.antimicrobe.org www.antimicrobe.org
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VGS are presumed to be uniformly susceptible to penicillin
Effective antibiotic: penicillin
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rarediseases.org rarediseases.org
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Related Disorders
Tularemia can be hard to differentiate from cat-scratch disease. May also present like the plague.
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www.humanillnesses.com www.humanillnesses.com
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Tularemia bacteria enter the body through the mucous membranes the skin, the lungs, or the digestive system. There are seven different forms of the disease:
Seven different forms of the disease --> based on how it is contracted and the symptoms it causes.
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How Do People Contract Rabbit Fever?
Get Tularemia through contact with infected animals. Not contagious from one human to another.
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www.cdc.gov www.cdc.gov
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Diagnostic testing
Grow F. tularensis in culture!
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