4 Matching Annotations
- Oct 2024
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FF6 binds to and activates μ-opioid receptors (MOR) at both low and physiological pH
It only activates in the targetted area. This makes it less addictive. The words used in this source is also more complex. There are terms in the study that I do not entirely understand. I had to look up some meanings of them.
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Chemical structures of fentanyl, N-{1-[2-(2,6-difluorphenyl)ethyl]piperidine-
example of how the atom was replaced
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two hydrogens were replaced by two fluorine atoms at the phenyl ring in the fentanyl structure
the changing of the atoms makes the opioid less addictive. The new opioid works in the targetted area instead of like a traditional opioid. The traditional opioid just releases everywhere, giving the brain that feeling of dopamine.
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strategy to preclude side effects.
to stop the harmful side effects of opioids
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