826 Matching Annotations
  1. May 2023
  2. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of BRAF and ERK1/2 has synergistic effects on thyroid cancer growth in vitro and in vivo
    1
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      DOI: 10.1002/mc.23284

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23284
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    Fluid shear stress generates a unique signaling response by activating multiple TGFβ family type I receptors in osteocytes
    1
    1. scibot 05 May 2023
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      DOI: 10.1096/fj.202001998R

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    Dynamics of cell rounding during detachment
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  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bruton's TK regulates myeloid cell recruitment during acute inflammation
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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    GM1 Oligosaccharide Efficacy in Parkinson’s Disease: Protection against MPTP
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      DOI: 10.3390/biomedicines11051305

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    Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
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      DOI: 10.1186/s12974-023-02784-z

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  9. Apr 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Regulation of sertoli cell function by planar cell polarity (PCP) protein Fjx1
    1
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      AB_329827

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    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
    1
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  12. www.thelancet.com www.thelancet.com
    Metabolic role of the hepatic valine/3-hydroxyisobutyrate (3-HIB) pathway in fatty liver disease
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    thelancet.com/journals/ebiom/article/PIIS2352-3964(23)00134-2/abstract
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    Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP3R2 circuit
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    Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes
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    Fructose-1,6-bisphosphatase is a nonenzymatic safety valve that curtails AKT activation to prevent insulin hyperresponsiveness
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  16. www.biorxiv.org www.biorxiv.org
    RhoB promotes Salmonella survival by regulating autophagy
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      DOI: 10.1101/2023.04.05.535690

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    Single targeting of MET in EGFR-mutated and MET-amplified non-small cell lung cancer
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    1. scibot 18 Apr 2023
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      DOI: 10.1038/s41416-023-02264-4

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  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
    1
    1. scibot 09 Apr 2023
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      DOI: 10.7554/eLife.78629

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  19. www.sciencedirect.com www.sciencedirect.com
    Adipocyte-derived chemerin rescues lipid overload-induced cardiac dysfunction
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    1. scibot 08 Apr 2023
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  20. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    Rapamycin treatment unmasks a sex-specific pattern of scar expansion of the infarcted rat heart: The relationship between mTOR and KATP channel
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      DOI: 10.1002/iub.2722

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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
    1
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      DOI: 10.1016/j.xcrm.2023.101007

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    sciencedirect.com/science/article/pii/S2666379123001179
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
    1
    1. scibot 05 Apr 2023
      RRID:AB_32982

      DOI: 10.1016/j.isci.2023.106355

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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of MicroRNA-23-27-24 Clusters Exhibits the Impairment of Myelination in the Central Nervous System
    1
    1. scibot 04 Apr 2023
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  24. Mar 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination
    1
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      DOI: 10.1016/j.celrep.2023.112296

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    sciencedirect.com/science/article/pii/S2211124723003078
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combining MEK and SRC inhibitors for treatment of colorectal cancer demonstrate increased efficacy in vitro but not in vivo
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      DOI: 10.1371/journal.pone.0281063

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    ncbi.nlm.nih.gov/pmc/articles/PMC10035898/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exercise-acclimated microbiota improves skeletal muscle metabolism via circulating bile acid deconjugation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10005909/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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      DOI: 10.1158/1541-7786.MCR-22-0090

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  29. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 Mar 2023
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  30. www.science.org www.science.org
    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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      DOI: 10.1126/sciadv.ade2540

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  31. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module
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    ncbi.nlm.nih.gov/pmc/articles/PMC9946360/
  33. Feb 2023
  34. www.mdpi.com www.mdpi.com
    Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-Induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment
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      DOI: 10.3390/antiox12020526

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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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  36. www.sciencedirect.com www.sciencedirect.com
    Chronic cortisol elevation restricts glucose uptake but not insulin responsiveness in zebrafish skeletal muscle
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  37. www.sciencedirect.com www.sciencedirect.com
    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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  38. www.nature.com www.nature.com
    Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models
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  39. 52.53.155.43 52.53.155.43
    bcd-22-0082-html.html
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Goji berry (Lycium barbarum) inhibits the proliferation, adhesion, and migration of oral cancer cells by inhibiting the ERK, AKT, and CyclinD cell signaling pathways: an in-vitro study
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    ncbi.nlm.nih.gov/pmc/articles/PMC9887205/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS Mutants Upregulate Integrin β4 to Promote Invasion and Metastasis in Colorectal Cancer
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      DOI: 10.1158/1541-7786.MCR-21-0994

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    An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation
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    sciencedirect.com/science/article/pii/S2451945623000260
  43. Jan 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development
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      DOI: 10.1016/j.immuni.2022.11.013

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    sciencedirect.com/science/article/pii/S1074761322006033
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    Multi-omics profiling visualizes dynamics of cardiac development and functions
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  132. www.sciencedirect.com www.sciencedirect.com
    Adipose mitochondrial metabolism controls body growth by modulating systemic cytokine and insulin signaling
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    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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    Patient-derived models of brain metastases recapitulate human disseminated disease
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    sciencedirect.com/science/article/pii/S2666379122001409
  135. Apr 2022
  136. www.sciencedirect.com www.sciencedirect.com
    Cerebroprotein hydrolysate injection is involved in promoting long-term angiogenesis, vessel diameter and density after cerebral ischemia in mice
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  137. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11
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    The hepatocyte insulin receptor is required to program the liver clock and rhythmic gene expression
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    SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation
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  142. aacrjournals.org aacrjournals.org
    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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  143. Mar 2022
  144. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
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  145. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proanthocyanidins Inhibit the Transmission of Spinal Pain Information Through a Presynaptic Mechanism in a Mouse Inflammatory Pain Model
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons
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  149. www.sciencedirect.com www.sciencedirect.com
    Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma
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  150. link.springer.com link.springer.com
    Interleukin-6 mimics insulin-dependent cellular distribution of some cytoskeletal proteins and Glut4 transporter without effect on glucose uptake in 3T3-L1 adipocytes
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  151. www.sciencedirect.com www.sciencedirect.com
    Creatine transport and creatine kinase activity is required for CD8+ T cell immunity
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    Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state
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  153. Feb 2022
  154. www.sciencedirect.com www.sciencedirect.com
    Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2
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    Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling
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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pigment Epithelium Derived Factor Is Involved in the Late Phase of Osteosarcoma Metastasis by Increasing Extravasation and Cell-Cell Adhesion
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  157. www.sciencedirect.com www.sciencedirect.com
    Renal Klotho and inorganic phosphate are extrinsic factors that antagonistically regulate hematopoietic stem cell maintenance
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    BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer
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  159. www.sciencedirect.com www.sciencedirect.com
    Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions
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    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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    The early reduction of left ventricular mass after sleeve gastrectomy depends on the fall of branched-chain amino acid circulating levels
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T63 induces apoptosis in nasopharyngeal carcinoma cells through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway
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  164. link.springer.com link.springer.com
    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
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  165. Jan 2022
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACE2 pathway regulates thermogenesis and energy metabolism
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  167. www.sciencedirect.com www.sciencedirect.com
    Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocyte-Specific Inhibition of Mir221/222 Ameliorates Diet-Induced Obesity Through Targeting Ddit4
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  169. www.sciencedirect.com www.sciencedirect.com
    The portrait of liver cancer is shaped by mitochondrial genetics
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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  171. Dec 2021
  172. www.sciencedirect.com www.sciencedirect.com
    The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
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  173. link.springer.com link.springer.com
    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes
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