465 Matching Annotations
  1. Nov 2022
  2. www.sciencedirect.com www.sciencedirect.com
    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.jcmgh.2022.09.006

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    sciencedirect.com/science/article/pii/S2352345X22001989
  3. www.cell.com www.cell.com
    Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111497

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    cell.com/cell-reports/abstract/S2211-1247(22)01347-X
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage
    1
    1. scibot 10 Nov 2022
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      DOI: 10.3389/fnagi.2022.967825

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    ncbi.nlm.nih.gov/pmc/articles/PMC9637852/
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
    1
    1. scibot 05 Nov 2022
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      DOI: 10.1007/s13402-022-00737-x

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    link.springer.com/article/10.1007/s13402-022-00737-x
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell intrinsic TIM-3 induces glioblastoma progression
    1
    1. scibot 04 Nov 2022
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      DOI: 10.1016/j.isci.2022.105329

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    ncbi.nlm.nih.gov/pmc/articles/PMC9618784/
  7. Oct 2022
  8. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
    2
    1. scibot 11 Oct 2022
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      DOI: 10.1016/j.devcel.2022.09.002

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      DOI: 10.1016/j.devcel.2022.09.002

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    sciencedirect.com/science/article/pii/S1534580722006323
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
    1
    1. scibot 02 Oct 2022
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      DOI: 10.1016/j.isci.2022.105118

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection
    1
    1. scibot 01 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111441

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474420/
  11. Sep 2022
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease
    1
    1. scibot 30 Sep 2022
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      DOI: 10.1016/j.isci.2022.105145

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513272/
  13. link.springer.com link.springer.com
    Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
    1
    1. scibot 15 Sep 2022
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      DOI: 10.1007/s11064-022-03751-5

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    link.springer.com/article/10.1007/s11064-022-03751-5
  14. www.sciencedirect.com www.sciencedirect.com
    Synergistic effect of mild traumatic brain injury and alcohol aggravates neuroinflammation, amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations: Impact on psychological stress
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    1. scibot 15 Sep 2022
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      DOI: 10.1016/j.expneurol.2022.114222

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    sciencedirect.com/science/article/pii/S0014488622002473
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of cGAS-STING pathway – A possible cause of myofiber atrophy/necrosis in dermatomyositis and immune-mediated necrotizing myopathy
    1
    1. scibot 09 Sep 2022
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      DOI: 10.1002/jcla.24631

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    onlinelibrary.wiley.com/doi/10.1002/jcla.24631
  16. Aug 2022
  17. www.sciencedirect.com www.sciencedirect.com
    STAT6 in mitochondrial outer membrane impairs mitochondrial fusion by inhibiting MFN2 dimerization
    1
    1. scibot 30 Aug 2022
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      DOI: 10.1016/j.isci.2022.104923

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    sciencedirect.com/science/article/pii/S2589004222011956
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Muscone and (+)-Borneol Cooperatively Strengthen CREB Induction of Claudin 5 in IL-1 β-Induced Endothelium Injury
    1
    1. scibot 26 Aug 2022
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      DOI: 10.3390/antiox11081455

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    ncbi.nlm.nih.gov/pmc/articles/PMC9394259/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-inflammatory effects of neutral lipids, glycolipids, phospholipids from Halocynthia aurantium tunic by suppressing the activation of NF-κB and MAPKs in LPS-stimulated RAW264.7 macrophages
    1
    1. scibot 22 Aug 2022
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      DOI: 10.1371/journal.pone.0270794

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    ncbi.nlm.nih.gov/pmc/articles/PMC9377571/
  20. www.sciencedirect.com www.sciencedirect.com
    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111225

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    sciencedirect.com/science/article/pii/S2211124722010427
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
    1. scibot 13 Aug 2022
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      DOI: 10.1016/j.cell.2016.07.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC5002269/
  22. www.sciencedirect.com www.sciencedirect.com
    Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling
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    1. scibot 12 Aug 2022
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      DOI: 10.1016/j.neuron.2022.07.015

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    sciencedirect.com/science/article/pii/S0896627322006602
  23. www.sciencedirect.com www.sciencedirect.com
    N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis
    1
    1. scibot 04 Aug 2022
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      DOI: 10.1016/j.devcel.2022.07.006

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    sciencedirect.com/science/article/pii/S1534580722004956
  24. www.sciencedirect.com www.sciencedirect.com
    CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder
    1
    1. scibot 04 Aug 2022
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      DOI: 10.1016/j.cmet.2022.07.005

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    sciencedirect.com/science/article/pii/S1550413122003047
  25. Jul 2022
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 29 Jul 2022
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      DOI: 10.1111/bph.15912

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      DOI: 10.1111/bph.15912

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15912
  27. www.sciencedirect.com www.sciencedirect.com
    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination
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    1. scibot 08 Jul 2022
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      DOI: 10.1016/j.isci.2022.104607

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    sciencedirect.com/science/article/pii/S2589004222008793
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Melatonin Inhibits NF-κB/CREB/Runx2 Signaling and Alleviates Aortic Valve Calcification
    1
    1. scibot 06 Jul 2022
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      DOI: 10.3389/fcvm.2022.885293

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    ncbi.nlm.nih.gov/pmc/articles/PMC9251177/
  29. Jun 2022
  30. www.sciencedirect.com www.sciencedirect.com
    The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
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    1. scibot 22 Jun 2022
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      DOI: 10.1016/j.isci.2022.104561

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    sciencedirect.com/science/article/pii/S2589004222008331
  31. www.sciencedirect.com www.sciencedirect.com
    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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    1. scibot 17 Jun 2022
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      DOI: 10.1016/j.isci.2022.104519

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    sciencedirect.com/science/article/pii/S2589004222007908
  32. academic.oup.com academic.oup.com
    Elevated levels of follicular fatty acids induce ovarian inflammation via ERK1/2 and inflammasome activation in PCOS
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1210/clinem/dgac281

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac281/6581607
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phloretin Protects Bovine Rumen Epithelial Cells from LPS-Induced Injury
    1
    1. scibot 01 Jun 2022
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      DOI: 10.3390/toxins14050337

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    ncbi.nlm.nih.gov/pmc/articles/PMC9147548/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
    1
    1. scibot 01 Jun 2022
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      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  35. May 2022
  36. www.nature.com www.nature.com
    Effects of interleukin 1β on long noncoding RNA and mRNA expression profiles of human synovial fluid derived mesenchymal stem cells
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    1. scibot 21 May 2022
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      DOI: 10.1038/s41598-022-12190-9

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    nature.com/articles/s41598-022-12190-9
  37. www.sciencedirect.com www.sciencedirect.com
    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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      DOI: 10.1016/j.celrep.2022.110796

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    sciencedirect.com/science/article/pii/S2211124722005630
  38. www.nature.com www.nature.com
    Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration
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      DOI: 10.1038/s41598-022-11116-9

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    nature.com/articles/s41598-022-11116-9
  39. www.sciencedirect.com www.sciencedirect.com
    Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer
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      DOI: 10.1016/j.ccell.2022.04.011

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    sciencedirect.com/science/article/pii/S1535610822001738
  40. Apr 2022
  41. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism
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      DOI: 10.1111/bph.15827

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15827
  42. www.sciencedirect.com www.sciencedirect.com
    Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension
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      DOI: 10.1016/j.isci.2022.104149

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    sciencedirect.com/science/article/pii/S2589004222004199
  43. www.sciencedirect.com www.sciencedirect.com
    Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
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      DOI: 10.1016/j.celrep.2022.110727

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    sciencedirect.com/science/article/pii/S2211124722004880
  44. www.sciencedirect.com www.sciencedirect.com
    Secreted NF-κB suppressive microbial metabolites modulate gut inflammation
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    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110646

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    sciencedirect.com/science/article/pii/S2211124722003989
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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      DOI: 10.1111/cns.13839

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    onlinelibrary.wiley.com/doi/10.1111/cns.13839
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control
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      DOI: 10.3389/fphar.2022.824138

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  47. Mar 2022
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    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
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    Indirubin-3’-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma
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    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
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    SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis
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    Baicalein—A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury
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    Corticotropin-releasing factor aggravates ischemic stroke injury by the inflammatory activation of microglia
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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    A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx
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    Age-associated decline of MondoA drives cellular senescence through impaired autophagy and mitochondrial homeostasis
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  61. Feb 2022
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    CD44 deficiency represses neuroinflammation and rescues dopaminergic neurons in a mouse model of Parkinson’s disease
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    Deletion of RNF186 expression suppresses diet-induced hepatic steatosis by regulating insulin activity
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    Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis
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  65. Jan 2022
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    Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
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    Sphingosine 1-phosphate receptor 4 promotes nonalcoholic steatohepatitis by activating NLRP3 inflammasome
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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    Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis
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  71. Dec 2021
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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    Toxoplasma gondii SAG1 Targeting Host Cell S100A6 for Parasite Invasion and Host Immunity
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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    CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
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    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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    Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation
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  83. Nov 2021
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    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
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  88. Oct 2021
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    St. John’s Wort alleviates dextran sodium sulfate-induced colitis through pregnane X receptor-dependent NFκB antagonism
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    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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  92. Sep 2021
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    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
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    Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model
    1
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  138. www.sciencedirect.com www.sciencedirect.com
    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
    1
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    sciencedirect.com/science/article/pii/S2211124721006392
  139. www.sciencedirect.com www.sciencedirect.com
    OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin
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      DOI: 10.1016/j.molcel.2021.05.031

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid
    1
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      DOI: 10.7554/eLife.67315

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    ncbi.nlm.nih.gov/pmc/articles/PMC8192125/
  141. www.embopress.org www.embopress.org
    Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy
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      DOI: 10.15252/emmm.202114059

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    embopress.org/doi/abs/10.15252/emmm.202114059
  142. www.hindawi.com www.hindawi.com
    HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice
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      DOI: 10.1155/2021/6620873

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  143. elifesciences.org elifesciences.org
    Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta
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  144. May 2021
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8144196/
  146. www.sciencedirect.com www.sciencedirect.com
    Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome
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    sciencedirect.com/science/article/pii/S2211124721005039
  147. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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  148. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Artemisinin inhibits TLR4 signaling by targeting co-receptor MD2 in microglial BV-2 cells and prevents lipopolysaccharide-induced blood–brain barrier leakage in mice
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15302
  149. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15384
  150. www.sciencedirect.com www.sciencedirect.com
    RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness
    1
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      Phospho-NF-κB p65 (Ser536) (clone 93H1)

      DOI: 10.1016/j.devcel.2021.04.022

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    sciencedirect.com/science/article/pii/S1534580721003609
  151. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    sciencedirect.com/science/article/pii/S0092867421004955
  152. www.spandidos-publications.com www.spandidos-publications.com
    Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition
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      DOI: 10.3892/or.2020.7463

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    spandidos-publications.com/10.3892/or.2020.7463
  153. www.sciencedirect.com www.sciencedirect.com
    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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      DOI: 10.1016/j.jconrel.2021.03.015

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    sciencedirect.com/science/article/pii/S0168365921001267
  154. www.sciencedirect.com www.sciencedirect.com
    Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells
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    sciencedirect.com/science/article/pii/S1534580721000708
  155. www.sciencedirect.com www.sciencedirect.com
    N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation
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      DOI: 10.1016/j.devcel.2020.10.023

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    sciencedirect.com/science/article/pii/S1534580720308431
  156. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function
    1
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      DOI: 10.1096/fj.202100087R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100087R
  157. Apr 2021
  158. www.sciencedirect.com www.sciencedirect.com
    TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
    1
    1. scibot 29 Apr 2021
      RRID:AB_331284

      DOI: 10.1016/j.cmet.2020.10.010

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    sciencedirect.com/science/article/pii/S155041312030543X
  159. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
    1
    1. scibot 29 Apr 2021
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      DOI: 10.1016/j.cmet.2020.05.008

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    sciencedirect.com/science/article/pii/S1550413120302473
  160. www.sciencedirect.com www.sciencedirect.com
    Coordinate regulation of the senescent state by selective autophagy
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    1. scibot 29 Apr 2021
      RRID:AB_331284

      DOI: 10.1016/j.devcel.2021.04.008

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  161. www.sciencedirect.com www.sciencedirect.com
    Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells
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      RRID:AB_331285

      DOI: 10.1016/j.cell.2020.02.003

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    sciencedirect.com/science/article/pii/S0092867420301471
  162. www.sciencedirect.com www.sciencedirect.com
    A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation
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      DOI: 10.1016/j.ccell.2021.02.003

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    sciencedirect.com/science/article/pii/S1535610821001057
  163. www.sciencedirect.com www.sciencedirect.com
    Inhibition of fibroblast IL-6 production by ACKR4 deletion alleviates cardiac remodeling after myocardial infarction
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      anti-Phospho-NF-κB p65

      DOI: 10.1016/j.bbrc.2021.02.013

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    sciencedirect.com/science/article/pii/S0006291X21001893
  164. www.sciencedirect.com www.sciencedirect.com
    Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING
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      RRID:AB_331284

      DOI: 10.1016/j.immuni.2021.03.011

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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic activation of spinal microglia triggers chronic pain in mice
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      DOI: 10.1371/journal.pbio.3001154

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  166. Mar 2021
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression
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      RRID:AB_331

      DOI: 10.1016/j.ebiom.2021.103283

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    ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
  168. academic.oup.com academic.oup.com
    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
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      DOI: 10.1093/biolre/ioaa203

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  169. Feb 2021
  170. www.sciencedirect.com www.sciencedirect.com
    Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease
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      RRID:AB_331284

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  171. www.cell.com www.cell.com
    Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies
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    cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
  172. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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      DOI: 10.1111/bph.15261

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  173. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission
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      DOI: 10.1111/jnc.15011

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15011
  174. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury
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    onlinelibrary.wiley.com/doi/10.1111/jcmm.14935
  175. www.sciencedirect.com www.sciencedirect.com
    Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy
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    sciencedirect.com/science/article/pii/S2211124721000644
  176. Jan 2021
  177. www.sciencedirect.com www.sciencedirect.com
    MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
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      DOI: 10.1016/j.celrep.2020.108628

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    sciencedirect.com/science/article/pii/S221112472031617X
  178. www.sciencedirect.com www.sciencedirect.com
    Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
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    sciencedirect.com/science/article/pii/S1535610820306607
  179. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_331284

      DOI: 10.1111/bph.15306

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
  180. Dec 2020
  181. www.sciencedirect.com www.sciencedirect.com
    Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease
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      RRID:AB_331284

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  182. Nov 2020
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BPS Publications
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    ncbi.nlm.nih.gov/pmc/articles/PMC7589013/
  184. Oct 2020
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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  186. link.springer.com link.springer.com
    Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation
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      DOI: 10.1007/s00011-020-01409-y

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  187. onlinelibrary.wiley.com onlinelibrary.wiley.com
    IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium
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      DOI: 10.1002/jcp.30103

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    onlinelibrary.wiley.com/doi/10.1002/jcp.30103
  188. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
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      DOI: 10.1016/j.cell.2020.09.020

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  189. Sep 2020
  190. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression
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  191. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Arctigenin protects mice from thioglycollate‐induced acute peritonitis
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  192. www.cell.com www.cell.com
    Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer
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      DOI: 10.1016/j.ccell.2019.12.012

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      DOI: 10.1016/j.ccell.2019.12.012

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    cell.com/cancer-cell/abstract/S1535-6108(19)30582-3
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    Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
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  194. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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    Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity
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      DOI: 10.1016/j.celrep.2020.107818

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    sciencedirect.com/science/article/pii/S2211124720307993
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    Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection
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      RRID:AB_331284

      DOI: 10.1016/j.chom.2020.01.023

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  197. www.sciencedirect.com www.sciencedirect.com
    The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis
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      RRID:AB_33128

      DOI: 10.1016/j.celrep.2020.108158

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  198. www.sciencedirect.com www.sciencedirect.com
    Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages
    1
    1. scibot 16 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.immuni.2020.03.006

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    sciencedirect.com/science/article/pii/S1074761320301199
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    1. scibot 16 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.03.029

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    sciencedirect.com/science/article/pii/S2211124720303430
  200. www.sciencedirect.com www.sciencedirect.com
    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
    1
    1. scibot 16 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.03.056

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    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
    1
    1. scibot 15 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.02.014

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    sciencedirect.com/science/article/pii/S2211124720301686
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    SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages
    1
    1. scibot 14 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.02.112

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    sciencedirect.com/science/article/pii/S221112472030293X
  203. www.cell.com www.cell.com
    Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling
    1
    1. scibot 13 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.immuni.2017.10.016

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    cell.com/immunity/abstract/S1074-7613(17)30471-5
  204. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Sep 2020
      RRID:AB_331284

      DOI: 10.1111/bph.15026

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    CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs
    1
    1. scibot 12 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.02.103

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    sciencedirect.com/science/article/pii/S2211124720302849
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    1. scibot 12 Sep 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.107840

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    sciencedirect.com/science/article/pii/S2211124720308214
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    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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      RRID:AB_331284

      DOI: 10.1016/j.celrep.2020.107547

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    sciencedirect.com/science/article/pii/S2211124720304575
  208. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      RRID:AB_331284

      DOI: 10.1111/bph.14972

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  209. academic.oup.com academic.oup.com
    DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice
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      RRID:AB_331284

      DOI: 10.1210/endocr/bqaa139

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    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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      DOI: 10.1016/j.cmet.2020.04.006

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      DOI: 10.1111/bph.14806

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    TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation
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      DOI: 10.1016/j.cmet.2020.03.007

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    Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration
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      DOI: 10.1016/j.celrep.2019.12.083

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    Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis
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      DOI: 10.1016/j.celrep.2020.107979

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    A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies
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      RRID:AB_331284

      DOI: 10.1111/bph.14809

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  216. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
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    1. scibot 03 Sep 2020
      phosphorylated RELA

      DOI: 10.1111/jcmm.15774

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  217. jvi.asm.org jvi.asm.org
    Middle East respiratory syndrome coronavirus nucleocapsid protein suppresses type I and type III interferon induction by targeting RIG-I signaling
    1
    1. scibot 03 Sep 2020
      phospho-NF-κB p65

      DOI: 10.1128/JVI.00099-20

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  218. www.jci.org www.jci.org
    Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT
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      anti–phospho-NF-κB p65

      DOI: 10.1172/JCI128994

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  219. Jan 2020
  220. www.cell.com www.cell.com
    Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury
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      RRID:AB_331284

      DOI: 10.1016/j.celrep.2019.09.050

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    cell.com/cell-reports/fulltext/S2211-1247(19)31238-0
  221. advances.sciencemag.org advances.sciencemag.org
    Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity
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    1. scibot 13 Jan 2020
      RRID:AB_331284

      DOI: 10.1126/sciadv.aau7802

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  222. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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    1. scibot 13 Jan 2020
      RRID:AB_331284

      DOI: 10.1016/j.immuni.2019.06.007

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    sciencedirect.com/science/article/pii/S1074761319302778
  223. www.sciencedirect.com www.sciencedirect.com
    NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor
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    1. scibot 13 Jan 2020
      RRID:AB_331284

      DOI: 10.1016/j.celrep.2019.09.087

      Resource: (Cell Signaling Technology Cat# 3033, RRID:AB_331284)

      Curator: @ethanbadger

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      RRID:AB_331284 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719312914
  224. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TAK1 inhibition in mouse astrocyte cultures ameliorates cytokine‐induced chemokine production and neutrophil migration
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    1. scibot 13 Jan 2020
      AB_331284

      DOI: 10.1111/jnc.14930

      Resource: (Cell Signaling Technology Cat# 3033, RRID:AB_331284)

      Curator: @Naa003

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      RRID:AB_331284 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14930
  225. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Jan 2020
      RRID:AB_331284

      DOI: 10.1111/bph.14713

      Resource: (Cell Signaling Technology Cat# 3033, RRID:AB_331284)

      Curator: @Naa003

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      RRID:AB_331284 RRIDCUR:Validated
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14713