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  1. Mar 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats
    1
    1. scibot 05 Mar 2023
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      DOI: 10.1152/ajpendo.00240.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8897003/
  3. onlinelibrary.wiley.com onlinelibrary.wiley.com
    COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by upregulating Krox20
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    1. scibot 03 Mar 2023
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      DOI: 10.1111/jnc.15764

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15764
  4. Feb 2023
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study
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    1. scibot 23 Feb 2023
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      DOI: 10.1002/cam4.5674

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    onlinelibrary.wiley.com/doi/10.1002/cam4.5674
  6. www.sciencedirect.com www.sciencedirect.com
    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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    1. scibot 16 Feb 2023
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      DOI: 10.1016/j.xcrp.2023.101296

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    sciencedirect.com/science/article/pii/S2666386423000553
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fibroblast growth factor-21 improves insulin action in nonlactating ewes
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    1. scibot 02 Feb 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC8816633/
  8. Jan 2023
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    1. scibot 20 Jan 2023
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
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    Controlling human organoid symmetry breaking reveals signaling gradients drive segmentation clock waves
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    1. scibot 19 Jan 2023
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      DOI: 10.1016/j.cell.2022.12.042

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    sciencedirect.com/science/article/pii/S0092867422015859
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
    1
    1. scibot 18 Jan 2023
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      DOI: 10.4103/1673-5374.355978

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma
    1
    1. scibot 12 Jan 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC9306355/
  13. royalsocietypublishing.org royalsocietypublishing.org
    Carbonic anhydrases in development: morphological observations and gene expression profiling in sea urchin embryos exposed to acetazolamide
    1
    1. scibot 08 Jan 2023
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      DOI: 10.1098/rsob.220254

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    royalsocietypublishing.org/doi/10.1098/rsob.220254
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.cell.2022.11.030

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    ncbi.nlm.nih.gov/pmc/articles/PMC9715480/
  15. Dec 2022
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Grpr expression defines a population of superficial dorsal horn vertical cells that have a role in both itch and pain
    1
    1. scibot 31 Dec 2022
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      DOI: 10.1097/j.pain.0000000000002677

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    ncbi.nlm.nih.gov/pmc/articles/PMC9756441/
  17. www.mdpi.com www.mdpi.com
    Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice
    1
    1. scibot 22 Dec 2022
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    mdpi.com/2073-4409/11/24/4116
  18. academic.oup.com academic.oup.com
    Membrane Estrogen Receptor Beta is Sufficient to Mitigate Cardiac Cell Pathology
    1
    1. scibot 22 Dec 2022
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      DOI: 10.1210/endocr/bqac200

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    academic.oup.com/endo/article/164/2/bqac200/6867852
  19. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
    1
    1. scibot 17 Dec 2022
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      DOI: 10.1016/j.ccell.2022.11.015

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    sciencedirect.com/science/article/pii/S1535610822005621
  20. www.sciencedirect.com www.sciencedirect.com
    Cav1.3 L-type Ca2+ channel-activated CaMKII/ERK2 pathway in the ventral tegmental area is required for cocaine conditioned place preference
    1
    1. scibot 06 Dec 2022
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      DOI: 10.1016/j.neuropharm.2022.109368

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    sciencedirect.com/science/article/pii/S0028390822004270
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The κ-opioid receptor-induced autophagy is implicated in stress-driven synaptic alterations
    1
    1. scibot 02 Dec 2022
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      DOI: 10.3389/fnmol.2022.1039135

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    ncbi.nlm.nih.gov/pmc/articles/PMC9709411/
  22. www.sciencedirect.com www.sciencedirect.com
    BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111728

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    sciencedirect.com/science/article/pii/S2211124722016060
  23. Nov 2022
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
    1. scibot 30 Nov 2022
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      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  25. www.sciencedirect.com www.sciencedirect.com
    Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
    1
    1. scibot 23 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111698

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    sciencedirect.com/science/article/pii/S2211124722015728
  26. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 20 Nov 2022
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      DOI: 10.1111/bph.15954

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15954
  27. academic.oup.com academic.oup.com
    mTOR inhibition decreases angiotensin II-induced steroidogenesis in HAC15 human adrenocortical carcinoma cells
    1
    1. scibot 19 Nov 2022
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      DOI: 10.1210/endocr/bqac185

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    academic.oup.com/endo/article/164/1/bqac185/6793711
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    B cell linker protein (BLNK) is a regulator of Met receptor signaling and trafficking in non-small cell lung cancer
    1
    1. scibot 18 Nov 2022
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      DOI: 10.1016/j.isci.2022.105419

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    ncbi.nlm.nih.gov/pmc/articles/PMC9646953/
  29. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
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    1. scibot 15 Nov 2022
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      DOI: 10.1126/sciadv.abn9912

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    science.org/doi/10.1126/sciadv.abn9912
  30. europepmc.org europepmc.org
    Antibody Registry: ten years of registering antibodies
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      RRID:AB_2315036

      DOI: 10.1093/nar/gkac927

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      DOI: 10.1093/nar/gkac927

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    europepmc.org/article/MED/36370112
  31. www.sciencedirect.com www.sciencedirect.com
    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
    1
    1. scibot 11 Nov 2022
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      DOI: 10.1016/j.ccell.2022.10.009

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    sciencedirect.com/science/article/pii/S1535610822005001
  32. www.sciencedirect.com www.sciencedirect.com
    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.jcmgh.2022.09.006

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    sciencedirect.com/science/article/pii/S2352345X22001989
  33. www.sciencedirect.com www.sciencedirect.com
    RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation
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    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.isci.2022.105184

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    sciencedirect.com/science/article/pii/S2589004222014560
  34. www.nature.com www.nature.com
    DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts
    1
    1. scibot 09 Nov 2022
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      DOI: 10.1038/s41388-022-02517-1

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    nature.com/articles/s41388-022-02517-1
  35. www.sciencedirect.com www.sciencedirect.com
    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    1. scibot 05 Nov 2022
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      DOI: 10.1016/j.ebiom.2022.104312

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    sciencedirect.com/science/article/pii/S2352396422004947
  36. www.sciencedirect.com www.sciencedirect.com
    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
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      DOI: 10.1016/j.celrep.2022.111581

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    sciencedirect.com/science/article/pii/S2211124722014462
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep
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      DOI: 10.3389/fphys.2022.954948

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    ncbi.nlm.nih.gov/pmc/articles/PMC9452821/
  38. Oct 2022
  39. www.sciencedirect.com www.sciencedirect.com
    TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways
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      DOI: 10.1016/j.cell.2022.09.033

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    sciencedirect.com/science/article/pii/S0092867422012521
  40. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein
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      DOI: 10.1016/j.celrep.2022.111545

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    sciencedirect.com/science/article/pii/S2211124722014012
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA
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      DOI: 10.1016/j.isci.2022.105182

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    ncbi.nlm.nih.gov/pmc/articles/PMC9563539/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain
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      DOI: 10.1042/BCJ20220308

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    ncbi.nlm.nih.gov/pmc/articles/PMC9555798/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia
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      DOI: 10.1016/j.isci.2022.105263

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579025/
  44. www.sciencedirect.com www.sciencedirect.com
    Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas
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      DOI: 10.1016/j.molcel.2022.09.024

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    sciencedirect.com/science/article/pii/S1097276522009340
  45. www.nature.com www.nature.com
    Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy
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      DOI: 10.1038/s41418-022-01072-2

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    nature.com/articles/s41418-022-01072-2
  46. Sep 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
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    Single-cell sequencing reveals activation of core transcription factors in PRC2-deficient malignant peripheral nerve sheath tumor
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    Behaviorally penetrant, anomalous dopamine efflux exposes sex and circuit dependent regulation of dopamine transporters
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    Anti-inflammatory effects of neutral lipids, glycolipids, phospholipids from Halocynthia aurantium tunic by suppressing the activation of NF-κB and MAPKs in LPS-stimulated RAW264.7 macrophages
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    S-nitrosylation is required for β2AR desensitization and experimental asthma
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    Ras Inhibitor Lonafarnib Rescues Structural and Functional Impairments of Synapses of Aβ1-42 Mice via α7nAChR-Dependent BDNF Upregulation
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  60. Jul 2022
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    Triple targeting of HER receptors overcomes heregulin-mediated resistance to EGFR blockade in colorectal cancer
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  83. Apr 2022
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    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    Copper bis(thiosemicarbazone) complexes modulate P-glycoprotein expression and function in human brain microvascular endothelial cells
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    Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation
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    FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer
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    Undercarboxylated Osteocalcin Improves Insulin-Stimulated Glucose Uptake in Muscles of Corticosterone-Treated Mice
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    3D-organoid culture supports differentiation of human CAR+ iPSCs into highly functional CAR T cells
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    Identification of the nucleotide-free state as a therapeutic vulnerability for inhibition of selected oncogenic RAS mutants
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    A Novel Mutation in the FSH Receptor (I423T) Affecting Receptor Activation and Leading to Primary Ovarian Failure
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  109. Dec 2021
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    Convergent cross-species pro-cognitive effects of RGH-235, a new potent and selective histamine H3 receptor antagonist/inverse agonist
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    CWI pathway participated in vegetative growth and pathogenicity through a downstream effector AflRlm1 in Aspergillus flavus
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    Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity
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    Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors
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    NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
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    Promoted Interaction of C/EBPα with Demethylated Cxcr3 Gene Promoter Contributes to Neuropathic Pain in Mice
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