129 Matching Annotations
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    Light-activated insulin receptor modulates neuronal plasticity and cerebellar-driven behavior
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  3. Jun 2026
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    The CD49b (ITGA2) collagen receptor excludes CD8+ T cell infiltration in pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2589004226018754
  5. May 2026
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    A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma
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  7. Apr 2026
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    Mosperafenib, a novel paradox breaker BRAF inhibitor with potent preclinical activity in BRAF mutated colorectal cancer
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    MiR-1202 increases radioresistance in nasopharyngeal carcinoma by targeting NAIF1/MAPK/ERK pathway
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    Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases
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  11. Mar 2026
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    MYCT1–IFITM2/3 interaction links endothelial endolysosomal trafficking to white adipose tissue expansion
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    IgE-dependent anaphylaxis is regulated by sphingolipid binding to activating and inhibitory CD300 family members
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    Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis
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  15. Dec 2025
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    Immunohistochemical distribution of extracellular signal-regulated kinase 1 and 2 (ERK1/2) in the rat carotid body
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    RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma
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    Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
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    EML4-ALK variant-specific genetic interactions shape lung tumorigenesis
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  21. Oct 2025
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    HUWE1 stimulates mTORC1 activity by enhancing Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis
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    RIT1 Drives Oncogenic Transformation and is an Actionable Target in Lung Adenocarcinoma
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    The immune response against cancer is modulated by stromal cell fibronectin
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    PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma
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    GEF-H1 drives breast cancer cells to tumor progression
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    The β2 adrenergic receptor cross-linked interactome identifies 14-3-3 proteins as regulating the availability of signaling-competent receptors
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    Overexpression of NR1D1 portends disease recurrence in thyroid cancer
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  35. Sep 2024
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    Functional Regeneration of the Sensory Root via Axonal Invasion
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    H3K9 lactylation in malignant cells facilitates CD8+ T cell dysfunction and poor immunotherapy response
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  39. Aug 2024
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    EGFR signaling coordinates patterning with cell survival during Drosophila epidermal development
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    Neuropeptide Y receptor activation preserves inner retinal integrity through PI3K/Akt signaling in a glaucoma mouse model
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  43. May 2024
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    The Human Intermediate Prolactin Receptor I-tail Contributes Breast Oncogenesis by Targeting Ras/MAPK Pathway
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  47. Apr 2024
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  50. Mar 2024
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    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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  52. Nov 2023
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    HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B
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    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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  56. Oct 2023
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    Hepatic safety profile of pancreatic cancer‑bearing mice fed a ketogenic diet in combination with gemcitabine
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  59. Sep 2023
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    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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  61. Jul 2023
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    A defective mechanosensing pathway affects fibroblast-to-myofibroblast transition in the old male mouse heart
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  63. Jun 2023
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    MEK inhibitor and anti-EGFR antibody overcome sotorasib resistance signals and enhance its antitumor effect in colorectal cancer cells
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    HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis
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    ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma
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    Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities
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  69. May 2023
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  71. Apr 2023
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  74. Jan 2023
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    Suppression of Insulin Receptor Substrate 1 Inhibits Breast Cancer Growth In Vitro and in Female Athymic Mice
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  76. Dec 2022
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    The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model
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    EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer
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  79. Nov 2022
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    Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions
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  82. Oct 2022
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    K+ channel Kv4.1 is expressed in the nociceptors/secondary nociceptive neurons and participates in pain regulation
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  85. Sep 2022
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  88. Aug 2022
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    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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  93. Jun 2022
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    Genetic screens identify a context-specific PI3K/p27Kip1 node driving extrahepatic biliary cancer
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  95. Apr 2022
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    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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  98. Mar 2022
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    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
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    Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: potential role of ADAM9
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  102. Feb 2022
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    BCL-XL inhibition induces an FGFR4-mediated rescue response in colorectal cancer
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    Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems
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  105. Jan 2022
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    Regulation of mouse primordial follicle formation by signaling through the PI3K pathway
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    Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair
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  108. Nov 2021
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    Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex
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  110. Sep 2021
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    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
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    Complement Factor B Mediates Ocular Angiogenesis through Regulating the VEGF Signaling Pathway
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  113. Aug 2021
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    TSH activates macrophage inflammation by G13 and G15-dependent pathways
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    High‐intensity treadmill running impairs cognitive behavior and hippocampal synaptic plasticity of rats via activation of inflammatory response
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  117. Jul 2021
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    Red nucleus interleukin‐1β evokes tactile allodynia through activation of JAK/STAT3 and JNK signaling pathways
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    Exogenous C-type natriuretic peptide therapy for impaired skeletal growth in a murine model of glucocorticoid treatment
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    Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma
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    Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption
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    Uncoupling of IL-6 signaling and LC3-associated phagocytosis drives immunoparalysis during sepsis
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  123. Jun 2021
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    TNAP is a novel regulator of cardiac fibrosis after myocardial infarction by mediating TGF-β/Smads and ERK1/2 signaling pathways
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