1,031 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-targeting JAK1/STAT6/GAS6/TAM signaling improves chemotherapy efficacy in Ewing sarcoma
    1
    1. scibot 25 Jun 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11192891/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The homeobox transcription factor DUXBL controls exit from totipotency
    1
    1. scibot 21 Jun 2024
      52961

      DOI: 10.1038/s41588-024-01692-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC11149696/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PPIA dictates NRF2 stability to promote lung cancer progression
    1
    1. scibot 21 Jun 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148020/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR/Cas9 screen reveals JunB downmodulation of HIV co-receptor CXCR4
    1
    1. scibot 21 Jun 2024
      52961

      DOI: 10.3389/fmicb.2024.1342444

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    ncbi.nlm.nih.gov/pmc/articles/PMC11149427/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven cancer
    1
    1. scibot 21 Jun 2024
      52961

      DOI: 10.21203/rs.3.rs-4390765/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11160912/
  7. www.sciencedirect.com www.sciencedirect.com
    Electron transport chain inhibition increases cellular dependence on purine transport and salvage
    1
    1. scibot 21 Jun 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.cmet.2024.05.014

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    sciencedirect.com/science/article/pii/S1550413124001906
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    An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing
    1
    1. scibot 21 Jun 2024
      Addgene_52961

      DOI: 10.1016/j.molcel.2024.05.017

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    sciencedirect.com/science/article/pii/S1097276524004404
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VCP regulates early tau seed amplification via specific cofactors
    1
    1. scibot 21 Jun 2024
      Addgene_52961

      DOI: 10.21203/rs.3.rs-4307848/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142303/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An efficient low cost means of biophysical gene transfection in primary cells
    1
    1. scibot 21 Jun 2024
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161637/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
    1
    1. scibot 21 Jun 2024
      Addgene_52961

      DOI: 10.1038/s41467-024-49391-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11161652/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A targetable PRR11-DHODH axis drives ferroptosis- and temozolomide-resistance in glioblastoma
    1
    1. scibot 20 Jun 2024
      52961

      DOI: 10.1016/j.redox.2024.103220

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    ncbi.nlm.nih.gov/pmc/articles/PMC11179629/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DPP3 promotes breast cancer tumorigenesis by stabilizing FASN and promoting lipid synthesis: DPP3 promotes breast cancer tumorigenesis
    1
    1. scibot 20 Jun 2024
      lentiCRISPR v2

      DOI: 10.3724/abbs.2024054

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    ncbi.nlm.nih.gov/pmc/articles/PMC11177116/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosomal 3q amplicon encodes essential regulators of secretory vesicles that drive secretory addiction in cancer
    1
    1. scibot 20 Jun 2024
      52961

      DOI: 10.1172/JCI176355

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    ncbi.nlm.nih.gov/pmc/articles/PMC11178546/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanistic patterns and clinical implications of oncogenic tyrosine kinase fusions in human cancers
    1
    1. scibot 20 Jun 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-49499-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11178778/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines
    1
    1. scibot 20 Jun 2024
      Addgene_52961

      DOI: 10.1186/s13073-024-01341-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11181638/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis
    1
    1. scibot 20 Jun 2024
      plasmid_52961

      DOI: 10.1073/pnas.2319301121

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    ncbi.nlm.nih.gov/pmc/articles/PMC11181076/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYG1 drives glycolysis and colorectal cancer development through nuclear-mitochondrial collaboration
    1
    1. scibot 15 Jun 2024
      LentiCRISPRv2

      DOI: 10.1038/s41467-024-49221-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11167044/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader
    1
    1. scibot 15 Jun 2024
      Plasmid_52961

      DOI: 10.1093/nar/gkae183

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    ncbi.nlm.nih.gov/pmc/articles/PMC11162783/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168
    1
    1. scibot 15 Jun 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-49431-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11169547/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-6 promotes tumor growth through immune evasion but is dispensable for cachexia
    1
    1. scibot 15 Jun 2024
      Addgene_52961

      DOI: 10.1038/s44319-024-00144-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11169252/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ileal Crohn’s Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway
    1
    1. scibot 15 Jun 2024
      RRID:Addgene_52961

      DOI: 10.3390/cells13110986

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    ncbi.nlm.nih.gov/pmc/articles/PMC11171731/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lysine acetyltransferase 14 mediates TGF-β-induced fibrosis in ovarian endometrioma via co-operation with serum response factor
    1
    1. scibot 14 Jun 2024
      RRID:Addgene_52961

      DOI: 10.1186/s12967-024-05243-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11167823/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 editing of synaptic genes in human embryonic stem cells for functional analysis in induced human neurons
    1
    1. scibot 10 Jun 2024
      52961

      DOI: 10.1016/j.xpro.2024.103089

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    ncbi.nlm.nih.gov/pmc/articles/PMC11152723/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer
    1
    1. scibot 10 Jun 2024
      lentiCRISPR v2

      DOI: 10.1038/s12276-024-01221-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148081/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling
    1
    1. scibot 10 Jun 2024
      52961

      DOI: 10.1038/s44318-024-00092-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148166/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the DYRK1A kinase prevents cancer progression and metastasis and promotes cancer cells response to G1/S targeting chemotherapy drugs
    1
    1. scibot 10 Jun 2024
      plasmid_52961

      DOI: 10.1038/s41698-024-00614-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11153725/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HMMR triggers immune evasion of hepatocellular carcinoma by inactivation of phagocyte killing
    1
    1. scibot 08 Jun 2024
      RRID:Addgene_52961

      DOI: 10.1126/sciadv.adl6083

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    ncbi.nlm.nih.gov/pmc/articles/PMC11152120/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
    1
    1. scibot 07 Jun 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11102494/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methods for investigating STAT3 regulation of lysosomal function in mammary epithelial cells
    1
    1. scibot 07 Jun 2024
      52961

      DOI: 10.1007/s10911-024-09563-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11102350/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR Screen Reveals PACT as a Pro-Viral Factor for Dengue Viral Replication
    1
    1. scibot 07 Jun 2024
      52961

      DOI: 10.3390/v16050725

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    ncbi.nlm.nih.gov/pmc/articles/PMC11125577/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCL8 Knockout: A Key to Resisting Pasteurella multocida Toxin-Induced Cytotoxicity
    1
    1. scibot 07 Jun 2024
      52961

      DOI: 10.3390/ijms25105330

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    ncbi.nlm.nih.gov/pmc/articles/PMC11121343/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bidirectional Non-Coding RNA Promoter Mediates Long-Range Gene Expression Regulation
    1
    1. scibot 07 Jun 2024
      plasmid_52961

      DOI: 10.3390/genes15050549

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    ncbi.nlm.nih.gov/pmc/articles/PMC11120797/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase
    1
    1. scibot 06 Jun 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11127050/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide in vivo CRISPR screen identifies TGFβ3 as actionable biomarker of palbociclib resistance in triple negative breast cancer
    1
    1. scibot 06 Jun 2024
      52,961

      DOI: 10.1186/s12943-024-02029-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145857/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Native and tagged CENP-A histones are functionally inequivalent
    1
    1. scibot 06 Jun 2024
      52,961

      DOI: 10.1186/s13072-024-00543-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145777/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tweaking the NRF2 signaling cascade in human myelogenous leukemia cells by artificial nano-organelles
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    1. scibot 06 Jun 2024
      52961

      DOI: 10.1073/pnas.2219470121

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    ncbi.nlm.nih.gov/pmc/articles/PMC11145192/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H2A.Z chaperones converge on E2F target genes for melanoma cell proliferation
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    1. scibot 06 Jun 2024
      52961

      DOI: 10.1101/gad.351318.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11146596/
  39. www.sciencedirect.com www.sciencedirect.com
    ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
    1
    1. scibot 04 Jun 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.canlet.2024.216999

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    sciencedirect.com/science/article/pii/S0304383524003938
  40. www.biorxiv.org www.biorxiv.org
    Alpha-defensin binding expands human adenovirus tropism
    1
    1. scibot 04 Jun 2024
      RRID:Addgene_52961

      DOI: 10.1101/2024.05.30.596681

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    biorxiv.org/content/10.1101/2024.05.30.596681v1
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting miR‐31 represses tumourigenesis and dedifferentiation of BRAFV600E‐associated thyroid carcinoma
    1
    1. scibot 03 Jun 2024
      52961

      DOI: 10.1002/ctm2.1694

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    ncbi.nlm.nih.gov/pmc/articles/PMC11128713/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Bivalent Gene POU4F1 Promotes and Maintains Basal‐like Breast Cancer
    1
    1. scibot 03 Jun 2024
      52 961

      DOI: 10.1002/advs.202307660

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    ncbi.nlm.nih.gov/pmc/articles/PMC11132042/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression
    1
    1. scibot 03 Jun 2024
      lenti-CRISPRv2

      DOI: 10.1038/s41467-024-49105-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11143236/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models
    1
    1. scibot 03 Jun 2024
      52961

      DOI: 10.1172/jci.insight.175462

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn’s disease with defective antimicrobial activity
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  48. May 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    FGD5 in basal cells induces CXCL14 secretion that initiates a feedback loop to promote murine mammary epithelial growth and differentiation
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  51. www.biorxiv.org www.biorxiv.org
    ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
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  52. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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  53. www.biorxiv.org www.biorxiv.org
    TRIM52 is a primate-specific player in the DNA repair process under tight proteolytic control by a triad of giant E3 ligases
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  54. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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  55. www.sciencedirect.com www.sciencedirect.com
    Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclin‐dependent kinase 12 deficiency reprogrammes cellular metabolism to alleviate ferroptosis potential and promote the progression of castration‐resistant prostate cancer
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocardial HDAC3 is required for myocardial trabeculation
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3–SLC36A1 axis promotes resistance to glucose starvation in kidney cancer cells
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify PKMYT1 as a therapeutic target in pancreatic ductal adenocarcinoma
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  62. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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  63. www.sciencedirect.com www.sciencedirect.com
    Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism
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  64. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRRSV degrades MDA5 via dual autophagy receptors P62 and CCT2 to evade antiviral innate immunity
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic context– and H2AK119 ubiquitination–dependent inheritance of human Polycomb silencing
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs
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  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-PK controls Apollo’s access to leading-end telomeres
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  71. www.biorxiv.org www.biorxiv.org
    Cysteine Rich Intestinal Protein 2 is a copper-responsive regulator of skeletal muscle differentiation
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  72. www.nature.com www.nature.com
    De novo generation of multi-target compounds using deep generative chemistry
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective CDK7 inhibition suppresses cell cycle progression and MYC signaling while enhancing apoptosis in therapy-resistant estrogen receptor positive breast cancer
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The epigenetic regulators EP300/CREBBP represent promising therapeutic targets in MLL-rearranged acute myeloid leukemia
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NFATC2IP is a mediator of SUMO-dependent genome integrity
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
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  79. elifesciences.org elifesciences.org
    Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Correlates of Venetoclax-Based Combination Sensitivities to Augment Acute Myeloid Leukemia Therapy
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  81. www.sciencedirect.com www.sciencedirect.com
    Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influenza Virus Reduces Ubiquitin E3 Ligase MARCH10 Expression to Decrease Ciliary Beat Frequency
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  84. www.science.org www.science.org
    The role of Piezo1 mechanotransduction in high-grade serous ovarian cancer: Insights from an in vitro model of collective detachment
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  85. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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  86. www.sciencedirect.com www.sciencedirect.com
    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2024.04.002

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    sciencedirect.com/science/article/pii/S1934590924001292
  87. Apr 2024
  88. www.sciencedirect.com www.sciencedirect.com
    Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia
    1
    1. scibot 30 Apr 2024
      AddgeneCAT# 52961

      DOI: 10.1016/j.celrep.2024.114152

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    sciencedirect.com/science/article/pii/S2211124724004807
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined SNPs sequencing and allele specific proteomics capture reveal functional causality underpinning the 2p25 prostate cancer susceptibility locus
    1
    1. scibot 30 Apr 2024
      52961

      DOI: 10.21203/rs.3.rs-3943095/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030545/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling
    1
    1. scibot 30 Apr 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11032371/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expansion of human centromeric arrays in cells undergoing break-induced replication
    1
    1. scibot 30 Apr 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034957/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CK2α-mediated phosphorylation of GRP94 facilitates the metastatic cascade in triple-negative breast cancer
    1
    1. scibot 30 Apr 2024
      LentiCRISPRv2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11035675/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMD1 promotes breast cancer aggressiveness via a spermidine-eIF5A hypusination-TCF4 axis
    1
    1. scibot 30 Apr 2024
      lentiCRISPR v2

      DOI: 10.1186/s13058-024-01825-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11040792/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYADM binds human parechovirus 1 and is essential for viral entry
    1
    1. scibot 30 Apr 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043367/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma
    1
    1. scibot 30 Apr 2024
      plasmid_52961

      DOI: 10.1093/hmg/ddae003

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    ncbi.nlm.nih.gov/pmc/articles/PMC11031357/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty acid-binding protein 5 is a functional biomarker and indicator of ferroptosis in cerebral hypoxia
    1
    1. scibot 30 Apr 2024
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039673/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of Piezo1 mechanotransduction in high-grade serous ovarian cancer: Insights from an in vitro model of collective detachment
    1
    1. scibot 30 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1126/sciadv.adl4463

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    ncbi.nlm.nih.gov/pmc/articles/PMC11051664/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prevention of age-related truncation of γ-glutamylcysteine ligase catalytic subunit (GCLC) delays cataract formation
    1
    1. scibot 30 Apr 2024
      plasmid_52961

      DOI: 10.1126/sciadv.adl1088

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    ncbi.nlm.nih.gov/pmc/articles/PMC11051666/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A MTA2-SATB2 chromatin complex restrains colonic plasticity toward small intestine by retaining HNF4A at colonic chromatin
    1
    1. scibot 30 Apr 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-47738-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11055869/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The E3 Ubiquitin Protein Ligase LINCR Amplifies the TLR-Mediated Signals through Direct Degradation of MKP1
    1
    1. scibot 29 Apr 2024
      lentiCRISPRv2

      DOI: 10.3390/cells13080687

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    ncbi.nlm.nih.gov/pmc/articles/PMC11048823/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SCFFBXW11 Complex Targets Interleukin-17 Receptor A for Ubiquitin–Proteasome-Mediated Degradation
    1
    1. scibot 29 Apr 2024
      52961

      DOI: 10.3390/biomedicines12040755

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    ncbi.nlm.nih.gov/pmc/articles/PMC11047997/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PMF-seq: a highly scalable screening strategy for linking genetics to mitochondrial bioenergetics
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11052718/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C
    1
    1. scibot 29 Apr 2024
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11046299/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of Ψ-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase
    1
    1. scibot 29 Apr 2024
      Addgene_52961

      DOI: 10.1038/s41467-024-47890-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053023/
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
    1
    1. scibot 29 Apr 2024
      Addgene_52961

      DOI: 10.3390/microorganisms12040660

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    ncbi.nlm.nih.gov/pmc/articles/PMC11052099/
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sprouty1 is a broad mediator of cellular senescence
    1
    1. scibot 29 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1038/s41419-024-06689-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11053034/
  107. www.sciencedirect.com www.sciencedirect.com
    Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
    1
    1. scibot 26 Apr 2024
      plasmid_52961

      DOI: 10.1016/j.cell.2024.03.022

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    sciencedirect.com/science/article/pii/S0092867424003131
  108. www.sciencedirect.com www.sciencedirect.com
    Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
    1
    1. scibot 25 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.xcrm.2024.101521

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    sciencedirect.com/science/article/pii/S2666379124001903
  109. www.sciencedirect.com www.sciencedirect.com
    Collagen IV assembly is influenced by fluid flow in kidney cell-derived matrices
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.cdev.2024.203923

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    sciencedirect.com/science/article/pii/S266729012400024X
  110. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
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    1. scibot 24 Apr 2024
      AddgeneCat# 52961

      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
    1
    1. scibot 24 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus 2 hijacks CMA-mediated lipolysis through upregulation of small GTPase RAB18
    1
    1. scibot 23 Apr 2024
      52961

      DOI: 10.1371/journal.ppat.1012123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014436/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer
    1
    1. scibot 23 Apr 2024
      lentiCRISPR v2

      DOI: 10.1038/s41467-024-47242-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009390/
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation
    1
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      52961

      DOI: 10.1093/nar/gkae094

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014252/
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic investigation of chemo-immunotherapy synergism to shift anti-PD-1 resistance in cancer
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11015024/
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmented ERO1α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11
    1
    1. scibot 23 Apr 2024
      Lenti-CRISPRv2

      DOI: 10.1186/s13046-024-03039-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11015652/
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unveiling IL6R and MYC as Targeting Biomarkers in Imatinib-Resistant Chronic Myeloid Leukemia through Advanced Non-Invasive Apoptosis Detection Sensor Version 2 Detection
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11011921/
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HOIL1 mediates MDA5 activation through ubiquitination of LGP2
    2
    1. scibot 23 Apr 2024
      52961

      DOI: 10.1101/2024.04.02.587772

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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014604/
  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HOIL-1L deficiency induces cell cycle alteration which causes immaturity of skeletal muscle and cardiomyocytes
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11024103/
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
    1
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      Addgene_52961

      DOI: 10.1073/pnas.2322563121

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009648/
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nerve growth factor receptor limits inflammation to promote remodeling and repair of osteoarthritic joints
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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC11018862/
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs
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    1. scibot 23 Apr 2024
      plasmid_52961

      DOI: 10.3389/fmolb.2023.1295507

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  123. www.sciencedirect.com www.sciencedirect.com
    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S1534580724002004
  124. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
    2
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      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.CAN-23-0555

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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  125. www.biorxiv.org www.biorxiv.org
    Pharmacogenomic discovery of genetically targeted cancer therapies optimized against clinical outcomes
    1
    1. scibot 19 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1101/2024.01.05.574245

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    biorxiv.org/content/10.1101/2024.01.05.574245v1
  126. aacrjournals.org aacrjournals.org
    Oncogenic KRAS drives lipo-fibrogenesis to promote angiogenesis and colon cancer progression
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    1. scibot 19 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1158/2159-8290.CD-22-1467

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    aacrjournals.org/cancerdiscovery/article/13/12/2652/731609/Oncogenic-KRAS-Drives-Lipofibrogenesis-to-Promote
  127. aacrjournals.org aacrjournals.org
    PRMT1 inhibition activates the interferon pathway to potentiate antitumor immunity and enhance checkpoint blockade efficacy in melanoma
    1
    1. scibot 19 Apr 2024
      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.CAN-23-1082

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    aacrjournals.org/cancerres/article/84/3/419/733846/PRMT1-Inhibition-Activates-the-Interferon-Pathway
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5
    1
    1. scibot 18 Apr 2024
      RRID:Addgene_52961

      DOI: 10.3390/ijms25073693

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  129. www.sciencedirect.com www.sciencedirect.com
    Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2024.114111

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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nek2A prevents centrosome clustering and induces cell death in cancer cells via KIF2C interaction
    1
    1. scibot 15 Apr 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944510/
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner
    1
    1. scibot 15 Apr 2024
      52961

      DOI: 10.7554/eLife.86727

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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification
    1
    1. scibot 15 Apr 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10946437/
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome
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      plasmid_52961

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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response
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      Addgene_52961

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma
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    1. scibot 15 Apr 2024
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10957915/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AURKA emerges as a vulnerable target for KEAP1-deficient non-small cell lung cancer by activation of asparagine synthesis
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      Addgene_52961

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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
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      Addgene_52961

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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993856/
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DePARylation is critical for S phase progression and cell survival
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    1. scibot 13 Apr 2024
      52961

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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I
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      52961

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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperative interaction of interferon regulatory factor -1 and bromodomain—containing protein 4 on RNA polymerase activation for intrinsic innate immunity
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      52961

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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interferon lambda restricts herpes simplex virus skin disease by suppressing neutrophil-mediated pathology
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      lentiCRISPRv2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11005406/
  143. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124721001972
  144. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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      AddgeneCat# 52961

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  145. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2666379124001733
  146. www.nature.com www.nature.com
    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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      RRID:Addgene_52961

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    nature.com/articles/s41419-024-06534-8
  147. www.sciencedirect.com www.sciencedirect.com
    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S1535610824000904
  148. www.sciencedirect.com www.sciencedirect.com
    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2024.114041

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    sciencedirect.com/science/article/pii/S2211124724003693
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10965441/
  150. Mar 2024
  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMP‐ACVR1 Axis is Critical for Efficacy of PRC2 Inhibitors in B‐Cell Lymphoma
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    1. scibot 31 Mar 2024
      Addgene_52961

      DOI: 10.1002/advs.202306499

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the receptor tyrosine kinase MerTK shows therapeutic value in gastric adenocarcinoma
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      Addgene_52961

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  153. www.sciencedirect.com www.sciencedirect.com
    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124724003267
  154. www.nature.com www.nature.com
    RBBP6 maintains glioblastoma stem cells through CPSF3-dependent alternative polyadenylation
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      RRID:Addgene_52961

      DOI: 10.1038/s41421-024-00654-3

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    nature.com/articles/s41421-024-00654-3
  155. www.sciencedirect.com www.sciencedirect.com
    DISRUPTION OF POLYUNSATURATED FATTY ACID BIOSYNTHESIS DRIVES STING-DEPENDENT ACUTE MYELOID LEUKEMIA CELL MATURATION AND DEATH
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      plasmid_52961

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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DNA methylation and B7-H3 in RB1-deficient and neuroendocrine prostate cancer
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    1. scibot 23 Mar 2024
      plasmid_52961

      DOI: 10.1126/scitranslmed.adf6732

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    ncbi.nlm.nih.gov/pmc/articles/PMC10954288/
  157. www.sciencedirect.com www.sciencedirect.com
    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
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      AddgeneCat#52961

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  158. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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      Addgene_52961

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  159. www.sciencedirect.com www.sciencedirect.com
    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    1. scibot 19 Mar 2024
      Addgene, Cat# 52961

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  160. www.sciencedirect.com www.sciencedirect.com
    A kinetic dichotomy between mitochondrial and nuclear gene expression processes
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      Addgene_52961

      DOI: 10.1016/j.molcel.2024.02.028

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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ubiquitin ligase subunit FBXO9 inhibits V-ATPase assembly and impedes lung cancer metastasis
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    1. scibot 17 Mar 2024
      LentiCRISPR v2

      DOI: 10.1186/s40164-024-00497-4

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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blocking TGF-β- and Epithelial-to-Mesenchymal Transition (EMT)-mediated activation of vessel-associated mural cells in glioblastoma impacts tumor angiogenesis
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      52961

      DOI: 10.17879/freeneuropathology-2024-5188

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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microtubule disruption synergizes with STING signaling to show potent and broad-spectrum antiviral activity
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      plentiCRISPR v2

      DOI: 10.1371/journal.ppat.1012048

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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth
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      lentiCRISPRv2

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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A SWI/SNF-dependent transcriptional regulation mediated by POU2AF2/C11orf53 at enhancer
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT5 is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An efficient and cost-effective method for disrupting genes in RAW264.7 macrophages using CRISPR-Cas9
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      plasmid_52961

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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 model of prostate cancer identifies Kmt2c deficiency as a metastatic driver by Odam/Cabs1 gene cluster expression
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      plasmid_52961

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of BRD4 Attenuates ER Stress-induced Renal Ischemic-Reperfusion Injury
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10929187/
  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Multiple Alternative Mitogenic Signaling Pathways Accompanies the Emergence of Drug-Tolerant Cancer Cells
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10930612/
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP22 regulates APL differentiation via PML-RARα stabilization and IFN repression
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      plasmid_52961

      DOI: 10.1038/s41420-024-01894-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10928094/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12
    1
    1. scibot 15 Mar 2024
      lentiCRISPR v2

      DOI: 10.1038/s44319-024-00071-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933290/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NSP6 inhibits the production of ACE2-containing exosomes to promote SARS-CoV-2 infectivity
    1
    1. scibot 15 Mar 2024
      plasmid_52961

      DOI: 10.1128/mbio.03358-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10936183/
  174. www.sciencedirect.com www.sciencedirect.com
    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
    1
    1. scibot 15 Mar 2024
      Addgene_52961

      DOI: 10.1016/j.celrep.2024.113945

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    sciencedirect.com/science/article/pii/S2211124724002730
  175. www.sciencedirect.com www.sciencedirect.com
    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
    3
    1. scibot 15 Mar 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2024.02.016

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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2024.02.016

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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2024.02.016

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    sciencedirect.com/science/article/pii/S1535610824000606
  176. www.nature.com www.nature.com
    Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis
    1
    1. scibot 14 Mar 2024
      RRID:Addgene_52961

      DOI: 10.1038/s41467-024-46386-6

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    nature.com/articles/s41467-024-46386-6
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IFI35 limits antitumor immunity in triple-negative breast cancer via CCL2 secretion
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    1. scibot 08 Mar 2024
      52961

      DOI: 10.1038/s41388-023-02934-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907302/
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology
    1
    1. scibot 08 Mar 2024
      lentiCRISPRv2

      DOI: 10.1038/s41590-024-01756-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907300/
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing
    1
    1. scibot 08 Mar 2024
      52961

      DOI: 10.1038/s41467-024-46114-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10908830/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Weakened APC/C activity at mitotic exit drives cancer vulnerability to KIF18A inhibition
    1
    1. scibot 08 Mar 2024
      52961

      DOI: 10.1038/s44318-024-00031-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10907621/
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variant to gene mapping for carpal tunnel syndrome risk loci implicates skeletal muscle regulatory elements
    1
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      52961

      DOI: 10.1016/j.ebiom.2024.105038

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    ncbi.nlm.nih.gov/pmc/articles/PMC10909706/
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication
    1
    1. scibot 08 Mar 2024
      Addgene_52961

      DOI: 10.1371/journal.ppat.1012014

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917307/
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma
    1
    1. scibot 08 Mar 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-45979-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912752/
  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer
    1
    1. scibot 07 Mar 2024
      lentiCRISPR v2

      DOI: 10.1007/s00018-023-05086-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912283/
  185. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of three CRISPR/Cas9 edited RB1 null hiPSC lines for retinoblastoma disease modelling
    1
    1. scibot 05 Mar 2024
      Plasmid_52961

      DOI: 10.1016/j.scr.2024.103373

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    sciencedirect.com/science/article/pii/S1873506124000710
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational response to mitochondrial stresses is orchestrated by tRNA modifications
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    1. scibot 02 Mar 2024
      52961

      DOI: 10.1101/2024.02.14.580389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10888749/
  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved ion channel function of STING mediates noncanonical autophagy and cell death
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    1. scibot 01 Mar 2024
      52961

      DOI: 10.1038/s44319-023-00045-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897221/
  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.7554/eLife.86168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901513/
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.1126/sciadv.adj4678

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901371/
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-MYC regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.1126/sciadv.adh8493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901375/
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
    1
    1. scibot 01 Mar 2024
      plasmid_52961

      DOI: 10.1186/s12929-024-01015-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  192. www.sciencedirect.com www.sciencedirect.com
    PEDV nucleocapsid antagonizes Zinc-finger Antiviral Protein by disrupting the interaction with its obligate co-factor, TRIM25.
    1
    1. scibot 01 Mar 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.vetmic.2024.110033

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    sciencedirect.com/science/article/pii/S0378113524000555
  193. Feb 2024
  194. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
    1
    1. scibot 29 Feb 2024
      AddgeneCat#52961

      DOI: 10.1016/j.isci.2024.109181

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    sciencedirect.com/science/article/pii/S2589004224004024
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation
    1
    1. scibot 29 Feb 2024
      52961

      DOI: 10.1101/2024.02.06.578742

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    ncbi.nlm.nih.gov/pmc/articles/PMC10871207/
  196. www.sciencedirect.com www.sciencedirect.com
    CRISPR editing to mimic porphyria combined with light: a new preclinical approach for prostate cancer
    1
    1. scibot 29 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.omton.2024.200772

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    sciencedirect.com/science/article/pii/S2950329924000146
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
    1
    1. scibot 29 Feb 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-46048-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879147/