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  1. Mar 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Variant to gene mapping for carpal tunnel syndrome risk loci implicates skeletal muscle regulatory elements
    1
    1. scibot 08 Mar 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10909706/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine circovirus type 2 infection promotes the SUMOylation of nucleophosmin-1 to facilitate the viral circular single-stranded DNA replication
    1
    1. scibot 08 Mar 2024
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917307/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma
    1
    1. scibot 08 Mar 2024
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912752/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer
    1
    1. scibot 07 Mar 2024
      lentiCRISPR v2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912283/
  6. www.sciencedirect.com www.sciencedirect.com
    Generation and characterization of three CRISPR/Cas9 edited RB1 null hiPSC lines for retinoblastoma disease modelling
    1
    1. scibot 05 Mar 2024
      Plasmid_52961

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    sciencedirect.com/science/article/pii/S1873506124000710
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational response to mitochondrial stresses is orchestrated by tRNA modifications
    1
    1. scibot 02 Mar 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10888749/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conserved ion channel function of STING mediates noncanonical autophagy and cell death
    1
    1. scibot 01 Mar 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897221/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.7554/eLife.86168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901513/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.1126/sciadv.adj4678

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901371/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-MYC regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia
    1
    1. scibot 01 Mar 2024
      52961

      DOI: 10.1126/sciadv.adh8493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901375/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
    1
    1. scibot 01 Mar 2024
      plasmid_52961

      DOI: 10.1186/s12929-024-01015-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  13. www.sciencedirect.com www.sciencedirect.com
    PEDV nucleocapsid antagonizes Zinc-finger Antiviral Protein by disrupting the interaction with its obligate co-factor, TRIM25.
    1
    1. scibot 01 Mar 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.vetmic.2024.110033

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    sciencedirect.com/science/article/pii/S0378113524000555
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma
    1
    1. scibot 29 Feb 2024
      AddgeneCat#52961

      DOI: 10.1016/j.isci.2024.109181

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    sciencedirect.com/science/article/pii/S2589004224004024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation
    1
    1. scibot 29 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10871207/
  17. www.sciencedirect.com www.sciencedirect.com
    CRISPR editing to mimic porphyria combined with light: a new preclinical approach for prostate cancer
    1
    1. scibot 29 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1016/j.omton.2024.200772

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    sciencedirect.com/science/article/pii/S2950329924000146
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
    1
    1. scibot 29 Feb 2024
      plasmid_52961

      DOI: 10.1038/s41467-024-46048-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879147/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular trafficking of HIV-1 Gag via Syntaxin 6-positive compartments/vesicles: Involvement in tumor necrosis factor secretion
    1
    1. scibot 28 Feb 2024
      Lenti-CRISPRv2

      DOI: 10.1016/j.jbc.2024.105687

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    ncbi.nlm.nih.gov/pmc/articles/PMC10891346/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Betacoronavirus OC43 Interferes with the Integrated Stress Response Pathway in Infected Cells
    1
    1. scibot 28 Feb 2024
      plasmid_52961

      DOI: 10.3390/v16020212

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    ncbi.nlm.nih.gov/pmc/articles/PMC10893100/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1038/s41467-024-45902-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10894237/
  22. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
    4
    1. scibot 23 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.can-23-0555

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      RRID:Addgene_52961

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      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.can-23-0555

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    4. scibot 23 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.can-23-0555

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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  23. 52.53.155.43 52.53.155.43
    419-html.html
    3
    1. scibot 23 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.can-23-1082

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      RRID:Addgene_52961

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      RRID:Addgene_52961

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    52.53.155.43/9ee9b923ebb85a391d8ef40b8ed2af8f0d12ae03/419-html.html
  24. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
    1
    1. scibot 22 Feb 2024
      Addgene Cat # 52961

      DOI: 10.1016/j.celrep.2024.113780

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    sciencedirect.com/science/article/pii/S2211124724001086
  25. www.biorxiv.org www.biorxiv.org
    New submission 27/09/2023, 09:17:54
    1
    1. scibot 21 Feb 2024
      52961

      DOI: 10.1101/2023.07.31.551317

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    biorxiv.org/content/10.1101/2023.07.31.551317v3
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Personalized allele-specific CRISPR-Cas9 strategies for myofibrillar myopathy 6
    1
    1. scibot 21 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10863003/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes
    1
    1. scibot 21 Feb 2024
      52961

      DOI: 10.1038/s41392-024-01754-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10866945/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hexokinase 1 and 2 mediates glucose utilization to regulate the synthesis of kappa casein via ribosome protein subunit 6 kinase 1 in bovine mammary epithelial cells
    1
    1. scibot 21 Feb 2024
      52961

      DOI: 10.1016/j.aninu.2024.01.001

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867561/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hijacking of nucleotide biosynthesis and deamidation-mediated glycolysis by an oncogenic herpesvirus
    1
    1. scibot 21 Feb 2024
      pLentiCRISPR v2

      DOI: 10.1038/s41467-024-45852-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873312/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex
    1
    1. scibot 21 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10873344/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1
    1
    1. scibot 21 Feb 2024
      lentiCRISPRV2

      DOI: 10.1186/s12967-024-04970-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10874581/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A landscape of gene expression regulation for synovium in arthritis
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      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10869817/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer
    1
    1. scibot 18 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1038/s43018-023-00539-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867901/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-derived Small Extracellular Vesicles Inhibit the Efficacy of CAR T Cells against Solid Tumors
    1
    1. scibot 16 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1158/0008-5472.CAN-22-2220

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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aggregability of the SQSTM1/p62-based aggresome-like induced structures determines the sensitivity to parthanatos
    1
    1. scibot 15 Feb 2024
      lenti-CRISPRv2

      DOI: 10.1038/s41420-024-01838-2

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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10864035/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX2 Expression Does Not Guarantee Cancer Stem Cell-like Characteristics in Lung Adenocarcinoma
    1
    1. scibot 15 Feb 2024
      plasmid_52961

      DOI: 10.3390/cells13030216

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    ncbi.nlm.nih.gov/pmc/articles/PMC10854781/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and epigenomic basis of breast invasive lobular carcinomas lacking CDH1 genetic alterations
    1
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      Addgene_52961

      DOI: 10.1038/s41698-024-00508-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861500/
  39. www.biorxiv.org www.biorxiv.org
    DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin
    1
    1. scibot 15 Feb 2024
      Addgene_52961

      DOI: 10.1101/2024.02.06.579191

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    biorxiv.org/content/10.1101/2024.02.06.579191v1
  40. www.biorxiv.org www.biorxiv.org
    Circadian period is compensated for repressor protein turnover rates in single cells
    1
    1. scibot 15 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1101/2024.02.06.579141

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    biorxiv.org/content/10.1101/2024.02.06.579141v1
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting epigenetic targets to overcome taxane resistance in prostate cancer
    1
    1. scibot 15 Feb 2024
      Addgene_52961

      DOI: 10.1038/s41419-024-06422-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861560/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tubeimosides are pan-coronavirus and filovirus inhibitors that can block their fusion protein binding to Niemann-Pick C1
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    1. scibot 13 Feb 2024
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance
    1
    1. scibot 13 Feb 2024
      lentiCRISPR v2

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  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
    1
    1. scibot 13 Feb 2024
      lentiCRISPR v2

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Constitutive Plasma Membrane Turnover in T-REx293 cells via Ordered Membrane Domain Endocytosis under Mitochondrial Control
    1
    1. scibot 13 Feb 2024
      52961

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EBV abortive lytic cycle promotes nasopharyngeal carcinoma progression through recruiting monocytes and regulating their directed differentiation
    1
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      52961

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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A small-molecule degrader selectively inhibits the growth of ALK-rearranged lung cancer with ceritinib resistance
    1
    1. scibot 10 Feb 2024
      Addgene_52961

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism
    1
    1. scibot 09 Feb 2024
      plasmid_52961

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  49. www.biorxiv.org www.biorxiv.org
    RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4
    2
    1. scibot 09 Feb 2024
      RRID:Addgene_52961

      DOI: 10.1101/2023.12.10.570873

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  50. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
      RRID:Addgene_52961

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice
    1
    1. scibot 08 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762000/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses
    1
    1. scibot 08 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10764363/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
    1
    1. scibot 08 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10764958/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nuclear membrane protein SUN2 promotes replication of flaviviruses through modulating cytoskeleton reorganization mediated by NS1
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10766649/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer immunochemotherapy
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10766965/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin-1 induces Axin degradation via the LRP6-CK1ε axis
    1
    1. scibot 08 Feb 2024
      LentiCRISPRv2

      DOI: 10.1186/s12964-023-01456-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10768284/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transforming Growth Factor-β/Smad Signaling Inhibits Melanoma Cancer Stem Cell Self-Renewal, Tumor Formation and Metastasis
    1
    1. scibot 08 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10778361/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Screens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease
    1
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      Addgene_52961

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  59. www.sciencedirect.com www.sciencedirect.com
    p53 promotes antiviral innate immunity by driving hexosamine metabolism
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124724000524
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The heterogeneity of signaling pathways and drug responses in intrahepatic cholangiocarcinoma with distinct genetic mutations
    1
    1. scibot 06 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10784283/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders
    1
    1. scibot 05 Feb 2024
      52961

      DOI: 10.1172/JCI170054

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    ncbi.nlm.nih.gov/pmc/articles/PMC10786691/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biallelic Cys141Tyr variant of SEL1L is associated with neurodevelopmental disorders, agammaglobulinemia, and premature death
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10786703/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10789791/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SEL1L-HRD1 ER-associated degradation regulates leptin receptor maturation and signaling in POMC neurons in diet-induced obesity
    1
    1. scibot 05 Feb 2024
      52961

      DOI: 10.21203/rs.3.rs-3768472/v1

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  65. www.biorxiv.org www.biorxiv.org
    Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer
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      52961

      DOI: 10.1101/2024.01.10.574969

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    biorxiv.org/content/10.1101/2024.01.10.574969v1
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NatD epigenetically activates FOXA2 expression to promote breast cancer progression by facilitating MMP14 expression
    1
    1. scibot 05 Feb 2024
      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830889/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
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      52961

      DOI: 10.26508/lsa.202302424

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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing of latrophilin-3 controls synapse formation
    1
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      52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830413/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone resorption by osteoclasts involves fine tuning of RHOA activity by its microtubule-associated exchange factor GEF-H1
    1
    1. scibot 04 Feb 2024
      RRID:Addgene_52961

      DOI: 10.3389/fphys.2024.1342024

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  70. www.nature.com www.nature.com
    Activation of recombinases at specific DNA loci by zinc-finger domain insertions
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      RRID:Addgene_52961

      DOI: 10.1038/s41587-023-02121-y

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5 facilitates bladder cancer progression by stabilizing the c-Jun protein
    1
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      52,961

      DOI: 10.1186/s12935-024-03222-7

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification
    1
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      52961

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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EPAC1 enhances brown fat growth and beige adipogenesis
    1
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      52961

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations accumulated in the Spike of SARS-CoV-2 Omicron allow for more efficient counteraction of the restriction factor BST2/Tetherin
    1
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      52961

      DOI: 10.1371/journal.ppat.1011912

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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis
    1
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer
    1
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      Addgene_52961

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  77. Jan 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
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      plasmid_52961

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset
    1
    1. scibot 30 Jan 2024
      Addgene, Watertown, MA, #52961

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL
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      plasmid_52961

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The LKB1–TSSK1B axis controls YAP phosphorylation to regulate the Hippo–YAP pathway
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    1. scibot 30 Jan 2024
      plasmid_52961

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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas
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      plasmid_52961

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HPV16 E6 Oncogene Contributes to Cancer Immune Evasion by Regulating PD-L1 Expression through a miR-143/HIF-1a Pathway
    1
    1. scibot 29 Jan 2024
      Addgene_52961

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  84. www.sciencedirect.com www.sciencedirect.com
    ATG14 plays a critical role in hepatic lipid droplet homeostasis
    1
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      RRID: Addgene_52,961

      DOI: 10.1016/j.metabol.2023.155693

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    EXO1 protects BRCA1-deficient cells against toxic DNA lesions
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    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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    Endothelial Jagged1 levels and distribution are post-transcriptionally controlled by ZFP36 decay proteins
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    Dynamic IL-6R/STAT3 signaling leads to heterogeneity of metabolic phenotype in pancreatic ductal adenocarcinoma cells
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    RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4
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    Human inherited CCR2 deficiency underlies progressive polycystic lung disease
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    KIF16B Mediates Anterograde Transport and Modulates Lysosomal Degradation of the HIV-1 Envelope Glycoprotein
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    Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function
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    Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth
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    High-throughput PRIME-editing screens identify functional DNA variants in the human genome
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    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    Autophagy supports PDGFRA-dependent brain tumor development by enhancing oncogenic signaling
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    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
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    Metixene is an incomplete autophagy inducer in preclinical models of metastatic cancer and brain metastases
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    Stem cell quiescence requires PRC2/PRC1-mediated mitochondrial checkpoint
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    Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Copy-back viral genomes induce a cellular stress response that interferes with viral protein expression without affecting antiviral immunity
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    Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability
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    Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype
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    Drug dependence in cancer is exploitable by optimally constructed treatment holidays
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    De novo lipogenesis pathway is a vulnerability in IDH1 mutant glioma
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    Generation of a human embryonic stem cell reporter line, TMEM119-EGFP, for the visualisation of in vitro differentiated human microglia
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    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
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    Targeting DNA methylation and B7-H3 in RB1-deficient and neuroendocrine prostate cancer
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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    SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing
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    Genome-wide CRISPR activation screening in senescent cells reveals SOX5 as a driver and therapeutic target of rejuvenation
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    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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    Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination
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    Synaptic Activity Causes Minute-scale Changes in BAF Complex Composition and Function
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    Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer
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  125. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9-Mediated CtBP1 Gene Editing Enhances Chemosensitivity and Inhibits Metastatic Potential in Esophageal Squamous Cell Carcinoma Cells
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  127. Sep 2023
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    Essential role of the amino-terminal region of Drosha for the Microprocessor function
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    Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping
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  130. www.embopress.org www.embopress.org
    IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy
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  131. www.tandfonline.com www.tandfonline.com
    A conserved HOTAIRM1-HOXA1 regulatory axis contributes early to neuronal differentiation
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  132. dx.doi.org dx.doi.org
    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    microRNAs slow translating ribosomes to prevent protein misfolding in eukaryotes
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  134. dx.doi.org dx.doi.org
    Loss of CDKN2A Cooperates with WWTR1(TAZ)–CAMTA1 Gene Fusion to Promote Tumor Progression in Epithelioid Hemangioendothelioma
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ER-trafficking triggers NRF1 ubiquitination to promote its proteolytic activation
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  136. www.sciencedirect.com www.sciencedirect.com
    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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  137. www.sciencedirect.com www.sciencedirect.com
    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
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  138. Aug 2023
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMC3 epigenetic silencing regulates Rab27a expression and drives pancreatic cancer progression
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors
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  141. www.nature.com www.nature.com
    Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells
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  142. www.sciencedirect.com www.sciencedirect.com
    Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples
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  143. link.springer.com link.springer.com
    The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication
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  144. link.springer.com link.springer.com
    Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Porcine reproductive and respiratory syndrome virus upregulates SMPDL3B to promote viral replication by modulating lipid metabolism
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  146. 52.53.155.43 52.53.155.43
    Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses
    3
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  147. 52.53.155.43 52.53.155.43
    jcs260990-html.html
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle
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  150. www.sciencedirect.com www.sciencedirect.com
    FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth
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  151. Jul 2023
  152. www.embopress.org www.embopress.org
    Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells
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  153. www.embopress.org www.embopress.org
    Interferon inhibits a model RNA virus via a limited set of inducible effector genes
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  154. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer
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  156. www.sciencedirect.com www.sciencedirect.com
    A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling
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  157. www.sciencedirect.com www.sciencedirect.com
    Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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  160. www.nature.com www.nature.com
    Kinome-wide CRISPR-Cas9 knockout screens revealed PLK1 as a therapeutic target for osteosarcoma
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  161. www.sciencedirect.com www.sciencedirect.com
    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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  162. 52.53.155.43 52.53.155.43
    qiad076-html.html
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-reactivity of anti-human programmed cell death ligand 1 (PD-L1) monoclonal antibody, clone 28-8 against feline PD-L1
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  164. www.sciencedirect.com www.sciencedirect.com
    Oncogenic K-Ras suppresses global miRNA function
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  165. Jun 2023
  166. www.sciencedirect.com www.sciencedirect.com
    Microbiota-produced indole metabolites disrupt mitochondrial function and inhibit Cryptosporidium parvum growth
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  167. 52.53.155.43 52.53.155.43
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  168. www.sciencedirect.com www.sciencedirect.com
    A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy
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  169. www.nature.com www.nature.com
    Extracellular vesicle-associated IGF2BP3 tunes Ewing sarcoma cell migration and affects PI3K/Akt pathway in neighboring cells
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  170. www.nature.com www.nature.com
    The effect of inhibition of receptor tyrosine kinase AXL on DNA damage response in ovarian cancer
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  171. www.sciencedirect.com www.sciencedirect.com
    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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  172. www.sciencedirect.com www.sciencedirect.com
    FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
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  174. www.biorxiv.org www.biorxiv.org
    Host ZCCHC3 blocks HIV-1 infection and production by a dual mechanism
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  175. www.biorxiv.org www.biorxiv.org
    IKKα kinase coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy
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  176. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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      DOI: 10.15252/embr.202256492

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  177. www.sciencedirect.com www.sciencedirect.com
    Acetate controls endothelial-to-mesenchymal transition
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  178. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial iron-responsive pathway regulated by DELE1
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploring the Immunogenicity of Noncanonical HLA-I Tumor Ligands Identified through Proteogenomics
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      DOI: 10.1158/1078-0432.CCR-22-3298

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  180. www.sciencedirect.com www.sciencedirect.com
    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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  181. dx.doi.org dx.doi.org
    EBV-upregulated B7-H3 inhibits NK cell-mediated antitumor function and contributes to nasopharyngeal carcinoma progression
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      RRID:Addgene_52961

      DOI: 10.1158/2326-6066.CIR-22-0374

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  182. dx.doi.org dx.doi.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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      DOI: 10.1158/2159-8290.CD-22-0825

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  183. dx.doi.org dx.doi.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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      DOI: 10.1158/1541-7786.MCR-22-0554

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  184. www.sciencedirect.com www.sciencedirect.com
    Acid-adapted cancer cells alkalinize their cytoplasm by degrading the acid-loading membrane transporter anion exchanger 2, SLC4A2
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2023.112601

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  185. www.embopress.org www.embopress.org
    STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interplay between Furin and Sialoglycans in Modulating Adeno-Associated Viral Cell Entry
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      DOI: 10.1128/jvi.00093-23

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  187. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dual VEGFA/BRAF targeting boosts PD-1 blockade in melanoma through GM-CSF-mediated infiltration of M1 macrophages
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  188. May 2023
  189. www.sciencedirect.com www.sciencedirect.com
    EWSR1 maintains centromere identity
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      Plasmid_52961

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  190. www.sciencedirect.com www.sciencedirect.com
    CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
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      RRID:Addgene_52961

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  191. www.biorxiv.org www.biorxiv.org
    Copyback viral genomes trigger stress granule formation independent of the antiviral response to interfere with viral translation in acute and persistent infections
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      DOI: 10.1101/2023.05.17.541157

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  192. www.sciencedirect.com www.sciencedirect.com
    Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization
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      DOI: 10.7554/eLife.85167

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  194. www.biorxiv.org www.biorxiv.org
    Electron transport chain inhibition increases cellular dependence on purine transport and salvage
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      RRID:Addgene_52961

      DOI: 10.1101/2023.05.11.540429

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  195. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-independent proteasomal degradation driven by C-degron pathways
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  196. www.sciencedirect.com www.sciencedirect.com
    Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis
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      Plasmid_52961

      DOI: 10.1016/j.isci.2023.106791

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  197. www.sciencedirect.com www.sciencedirect.com
    MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
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      RRID: Addgene_52961

      DOI: 10.1016/j.celrep.2023.112484

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      DOI: 10.1016/j.celrep.2023.112484

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    sciencedirect.com/science/article/pii/S2211124723004953
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized metrics for orthogonal combinatorial CRISPR screens
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      RRID:Addgene_52961

      DOI: 10.1038/s41598-023-34597-8

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