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Centromeric tandem repeats expansions in plateau zokor enhance chromosome stability for high-altitude adaptation

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1. scibot 08 Oct 2026
  
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  plasmid_52
  
  DOI: 10.1186/s13059-026-04159-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13276996/
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G-quadruplex structures are key regulators of mammalian spermatogenesis

1
1. scibot 07 Oct 2026
  
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  Addgene_52
  
  DOI: 10.1186/s11658-025-00839-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12865992/
Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer

1
1. scibot 19 Sep 2026
  
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  Addgene_52
  
  DOI: 10.1186/s12943-023-01788-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10199551/
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Hypoxic conditions confer chemoresistance to crizotinib but not to imatinib in chronic myeloid leukemia cells

1
1. scibot 26 Jan 2026
  
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  plasmid_52
  
  DOI: 10.1016/j.htct.2025.106240
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12818218/
Dec 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

1
1. scibot 11 Dec 2025
  
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  plasmid_52
  
  DOI: 10.1002/advs.202519698
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519698
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Loss of NcBPK1 impairs bradyzoite differentiation and enhances virulence in Neospora caninum

1
1. scibot 24 Nov 2025
  
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  Addgene_52
  
  DOI: 10.1186/s13071-025-07076-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12542182/
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CXCL8 mediates macrophage migration in canine oral malignant melanoma

1
1. scibot 24 Nov 2025
  
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  plasmid_52
  
  DOI: 10.1038/s41598-025-22749-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12592495/
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A matrix stiffness gene signature identifies SLC20A1 as a novel mechano-immunological checkpoint enabling synergistic immunotherapy in pancreatic ductal adenocarcinoma

1
1. scibot 24 Nov 2025
  
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  Addgene_52
  
  DOI: 10.1007/s00262-025-04195-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12612327/
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening

1
1. scibot 22 Sep 2025
  
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  Addgene_52
  
  DOI: 10.1186/s13059-025-03737-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12445041/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CLIC2 regulates immunosuppression and macrophage differentiation in genomically stable gastric cancer

1
1. scibot 24 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1186/s13062-025-00666-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12282021/
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Engineering biomimetic bone marrow niche with gene modified mesenchymal stromal cells for ex vivo culture of human hematopoietic stem and progenitor cells

1
1. scibot 20 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1186/s13287-025-04474-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12211287/
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An improved immunoassay detects Aβ oligomers in human biofluids: their CSF levels rise with tau and phosphotau levels

1
1. scibot 20 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1186/s13195-025-01802-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12255133/
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The phosphatase PPM1F, a negative regulator of integrin activity, is essential for embryonic development and controls tumor cell invasion

1
1. scibot 20 Jul 2025
  
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  Addgene_52
  
  DOI: 10.1186/s12915-025-02254-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12180154/
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CDX2 loss in colorectal cancer cells is associated with invasive properties and tumor budding

1
1. scibot 20 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1038/s41598-025-07278-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12230109/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Circular RNA landscape in extracellular vesicles from human biofluids

1
1. scibot 17 Jul 2025
  
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  Addgene_52
  
  DOI: 10.1186/s13073-024-01400-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11526565/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

1
1. scibot 17 Jul 2025
  
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  Addgene_52
  
  DOI: 10.1186/s12964-025-02091-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11841277/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Hippo pathway promotes platinum-based chemotherapy by inhibiting MTF1-dependent heavy metal response

1
1. scibot 17 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1186/s12885-025-13661-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11806854/
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Proteome-wide microarray-based screening of PAR-binding proteins

1
1. scibot 17 Jul 2025
  
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  Addgene_52
  
  DOI: 10.1093/nar/gkaf300
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12000866/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Characterization of the adaptive immune response in a mouse model for HPV-positive head and neck squamous cell carcinoma with implications to human disease

1
1. scibot 17 Jul 2025
  
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  addgene_52
  
  DOI: 10.1007/s00262-024-03907-y
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11698698/
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Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR‐Altered Bladder Cancer

1
1. scibot 17 Jul 2025
  
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  Plasmid_52
  
  DOI: 10.1002/advs.202413209
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079435/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

1
1. scibot 17 Jul 2025
  
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  plasmid_52
  
  DOI: 10.1002/advs.202404938
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12120771/
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Dicer deficiency affects microglial function during demyelination and impairs remyelination

1
1. scibot 01 Apr 2025
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.nbd.2025.106879
  
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sciencedirect.com/science/article/pii/S0969996125000956
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer

1
1. scibot 28 Sep 2024
  
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  Addgene_52
  
  DOI: 10.1002/advs.202400140
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11425913/
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Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy

1
1. scibot 25 Sep 2024
  
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  plasmid_52
  
  DOI: 10.1186/s12943-024-02068-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11295332/
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The expression of PD-L1 on tumor-derived exosomes enhances infiltration and anti-tumor activity of αCD3 × αPD-L1 bispecific antibody-armed T cells

1
1. scibot 25 Sep 2024
  
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  plasmid_52
  
  DOI: 10.1007/s00262-024-03785-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11303351/
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Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

1
1. scibot 25 Sep 2024
  
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  Addgene_52
  
  DOI: 10.1186/s40478-024-01831-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11304869/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enzalutamide Sensitizes Castration‐Resistant Prostate Cancer to Copper‐Mediated Cell Death

1
1. scibot 25 Sep 2024
  
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  Addgene_52
  
  DOI: 10.1002/advs.202401396
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11321675/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines

1
1. scibot 25 Sep 2024
  
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  Addgene_52
  
  DOI: 10.1186/s13073-024-01341-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11181638/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy

1
1. scibot 25 Sep 2024
  
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  Addgene_52
  
  DOI: 10.1186/s12967-024-05235-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11138051/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF

1
1. scibot 25 Sep 2024
  
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  Plasmid_52
  
  DOI: 10.1007/s10565-024-09864-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039524/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dampened Regulatory Circuitry of TEAD1/ITGA1/ITGA2 Promotes TGFβ1 Signaling to Orchestrate Prostate Cancer Progression

1
1. scibot 25 Sep 2024
  
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  plasmid_52
  
  DOI: 10.1002/advs.202305547
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10953553/
www.sciencedirect.com www.sciencedirect.com

IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling

1
1. scibot 25 Sep 2024
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.cellsig.2023.110684
  
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sciencedirect.com/science/article/pii/S0898656823000980
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TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth

1
1. scibot 25 Sep 2024
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.jconrel.2022.07.004
  
  Resource: RRID:Addgene_52656
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S0168365922004138
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Mapping cis-regulatory elements in human neurons links psychiatric disease heritability and activity-regulated transcriptional programs

1
1. scibot 25 Sep 2024
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.celrep.2022.110877
  
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  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S2211124722006520
Aug 2024
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The effect of phosphorylation efficiency on the oncogenic properties of the protein E7 from high-risk HPV

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1. scibot 22 Aug 2024
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.virusres.2024.199446
  
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sciencedirect.com/science/article/pii/S0168170224001394
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functionally-instructed modifiers of response to ATR inhibition in experimental glioma

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1. scibot 15 Mar 2024
  
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  plasmid_52
  
  DOI: 10.1186/s13046-024-02995-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10935927/
Dec 2023
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FOXO1 regulates expression of Neurod4 in the pituitary gland

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1. scibot 29 Dec 2023
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.mce.2023.112128
  
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sciencedirect.com/science/article/pii/S0303720723002794
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Generation of a human embryonic stem cell reporter line, TMEM119-EGFP, for the visualisation of in vitro differentiated human microglia

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1. scibot 01 Dec 2023
  
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  plasmid_52
  
  DOI: 10.1016/j.scr.2023.103264
  
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sciencedirect.com/science/article/pii/S1873506123002507
Oct 2023
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Targeting doublecortin-like kinase 1 reveals a novel strategy to circumvent chemoresistance and metastasis in ovarian cancer

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1. scibot 13 Oct 2023
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.canlet.2023.216437
  
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sciencedirect.com/science/article/pii/S0304383523003889
Sep 2023
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Development of recombinant secondary antibody mimics (rSAMs) for immunoassays through genetic fusion of monomeric alkaline phosphatase with antibody binders

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1. scibot 27 Sep 2023
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.ijbiomac.2023.126299
  
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sciencedirect.com/science/article/pii/S0141813023031951
Feb 2023
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Lactate oxidase/vSIRPα conjugates efficiently consume tumor-produced lactates and locally produce tumor-necrotic H2O2 to suppress tumor growth

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1. scibot 15 Feb 2023
  
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  RRID:Addgene_52
  
  DOI: 10.1016/j.ijbiomac.2023.123577
  
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sciencedirect.com/science/article/pii/S0141813023004701
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Characterizing the metabolic role of STAT3 in canine osteosarcoma

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1. scibot 30 Dec 2022
  
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  RRID:Addgene_52
  
  DOI: 10.1111/vco.12841
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9669091/
Sep 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer

1
1. scibot 15 Sep 2022
  
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  RRID:Addgene_52
  
  DOI: 10.1111/cas.15558
  
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onlinelibrary.wiley.com/doi/10.1111/cas.15558
Jun 2022
elifesciences.org elifesciences.org

Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome

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1. scibot 11 Jun 2022
  
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  DOI: 10.7554/eLife.75166
  
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elifesciences.org/articles/75166
May 2022
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Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation

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1. scibot 28 May 2022
  
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  plasmid_52
  
  DOI: 10.1007/s00018-022-04312-3
  
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link.springer.com/article/10.1007/s00018-022-04312-3
Mar 2022
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Recruitment of DNA to tumor-derived microvesicles

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1. scibot 02 Mar 2022
  
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  plasmid_52
  
  DOI: 10.1016/j.celrep.2022.110443
  
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sciencedirect.com/science/article/pii/S221112472200170X
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

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1. scibot 06 Apr 2021
  
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  Addgene_52
  
  DOI: 10.1007/s00432-021-03601-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8017436/