28 Matching Annotations
  1. Apr 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ENGINEERED NANOBODIES WITH PROGRAMMABLE TARGET ANTIGEN PROTEOLYSIS (PTAP) FUSIONS REGULATE INTRACELLULAR ALPHA-SYNUCLEIN IN VITRO AND IN VIVO
    1
    1. scibot 23 Apr 2024
      52047

      DOI: 10.21203/rs.3.rs-4088206/v1

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      Curator: @olekpark

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996777/
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia
    1
    1. scibot 01 Feb 2024
      52047

      DOI: 10.1038/s41467-023-44264-1

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      Curator: @olekpark

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794252/
  5. Nov 2023
  6. www.sciencedirect.com www.sciencedirect.com
    An integrated in vitro human iPSCs-derived neuron and in vivo animal approach for preclinical screening of anti-seizure compounds
    1
    1. scibot 28 Nov 2023
      RRID:Addgene_52047

      DOI: 10.1016/j.jare.2023.11.022

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    sciencedirect.com/science/article/pii/S2090123223003612
  7. Oct 2023
  8. www.nature.com www.nature.com
    Chromatin-modifying enzymes as modulators of nuclear size during lineage differentiation
    1
    1. scibot 21 Oct 2023
      Addgene_52047

      DOI: 10.1038/s41420-023-01639-z

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    nature.com/articles/s41420-023-01639-z
  9. Sep 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths
    1
    1. scibot 06 Sep 2023
      plasmid_52047

      DOI: 10.1038/s41467-023-40803-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10475046/
  11. Aug 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons
    1
    1. scibot 30 Aug 2023
      RRID:Addgene_52047

      DOI: 10.1016/j.xgen.2023.100399

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    sciencedirect.com/science/article/pii/S2666979X23002136
  13. www.nature.com www.nature.com
    Efficient generation of functional neurons from mouse embryonic stem cells via neurogenin-2 expression
    1
    1. scibot 24 Aug 2023
      plasmid_52047

      DOI: 10.1038/s41596-023-00863-2

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    nature.com/articles/s41596-023-00863-2
  14. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
    1
    1. scibot 23 Aug 2023
      plasmid_52047

      DOI: 10.1016/j.celrep.2023.112994

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    sciencedirect.com/science/article/pii/S2211124723010057
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
    1
    1. scibot 10 Aug 2023
      Addgene_52047

      DOI: 10.1016/j.xpro.2023.102486

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    ncbi.nlm.nih.gov/pmc/articles/PMC10400954/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The efficient induction of human retinal ganglion-like cells provides a platform for studying optic neuropathies
    1
    1. scibot 10 Aug 2023
      RRID:Addgene_52047

      DOI: 10.1007/s00018-023-04890-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC10403410/
  17. Jan 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
    1
    1. scibot 19 Jan 2023
      RRID:Addgene_52047

      DOI: 10.1016/j.stem.2022.12.010

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    sciencedirect.com/science/article/pii/S1934590922004945
  19. Nov 2022
  20. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
    1
    1. scibot 24 Nov 2022
      RRID:Addgene_52047

      DOI: 10.1016/j.molcel.2022.11.002

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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  21. Oct 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons
    1
    1. scibot 19 Oct 2022
      RRID:Addgene_52047

      DOI: 10.1016/j.isci.2022.105187

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    ncbi.nlm.nih.gov/pmc/articles/PMC9574418/
  23. www.sciencedirect.com www.sciencedirect.com
    In vitro neurons learn and exhibit sentience when embodied in a simulated game-world
    1
    1. scibot 13 Oct 2022
      Addgene_52047

      DOI: 10.1016/j.neuron.2022.09.001

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    sciencedirect.com/science/article/pii/S0896627322008066
  24. Sep 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Molecular convergence between Down syndrome and fragile X syndrome identified using human pluripotent stem cell models
    1
    1. scibot 08 Sep 2022
      Addgene 52047

      DOI: 10.1016/j.celrep.2022.111312

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S2211124722011366
  26. Mar 2022
  27. www.nature.com www.nature.com
    APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons
    1
    1. scibot 05 Mar 2022
      plasmid_52047

      DOI: 10.1038/s41380-022-01454-5

      Resource: RRID:Addgene_52047

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    nature.com/articles/s41380-022-01454-5
  28. Oct 2021
  29. www.sciencedirect.com www.sciencedirect.com
    A synaptic temperature sensor for body cooling
    1
    1. scibot 21 Oct 2021
      52047

      DOI: 10.1016/j.neuron.2021.10.001

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      Curator: @Naa003

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      RRID:Addgene_52047 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0896627321007698
  30. Sep 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors
    1
    1. scibot 03 Sep 2021
      plasmid_52047

      DOI: 10.1016/j.neuron.2021.08.003

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    sciencedirect.com/science/article/pii/S089662732100578X
  32. Jul 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
    1
    1. scibot 31 Jul 2021
      plasmid_52047

      DOI: 10.1016/j.molcel.2018.11.028

      Resource: RRID:Addgene_52047

      Curator: @Naa003

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      RRID:Addgene_52047 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518309985
  34. www.sciencedirect.com www.sciencedirect.com
    Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses
    1
    1. scibot 30 Jul 2021
      FUW-TetO-Ng2-T2A-puromycin (lentiviral vector)

      DOI: 10.1016/j.cell.2019.09.011

      Resource: RRID:Addgene_52047

      Curator: @ethanbadger

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      RRID:Addgene_52047 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867419310177
  35. May 2021
  36. www.nature.com www.nature.com
    Neuron and astrocyte aggregation and sorting in three-dimensional neuronal constructs
    1
    1. scibot 22 May 2021
      RRID:Addgene_52047

      DOI: 10.1038/s42003-021-02104-2

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    nature.com/articles/s42003-021-02104-2
  37. Mar 2021
  38. www.sciencedirect.com www.sciencedirect.com
    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
    1
    1. scibot 22 Mar 2021
      RRID:Addgene_52047

      DOI: 10.1016/j.ccell.2021.01.005

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    sciencedirect.com/science/article/pii/S1535610821000490
  39. Feb 2021
  40. elifesciences.org elifesciences.org
    Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy
    1
    1. scibot 11 Feb 2021
      RRID:Addgene_52047

      DOI: 10.7554/eLife.64434

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      Curator: @evieth

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      RRID:Addgene_52047 RRIDCUR:Validated
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    elifesciences.org/articles/64434
  41. Dec 2020
  42. www.sciencedirect.com www.sciencedirect.com
    Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens
    1
    1. scibot 07 Dec 2020
      plasmid_52047

      DOI: 10.1016/j.celrep.2020.108460

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      Curator: @Naa003

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      RRIDCUR:Validated RRID:Addgene_52047
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    sciencedirect.com/science/article/pii/S2211124720314492
  43. www.sciencedirect.com www.sciencedirect.com
    Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia
    1
    1. scibot 07 Dec 2020
      Addgene_52047

      DOI: 10.1016/j.xpro.2020.100190

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      RRIDCUR:Validated RRID:Addgene_52047
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    sciencedirect.com/science/article/pii/S2666166720301775
  44. Sep 2020
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52047

      DOI: 10.1523/JNEUROSCI.0642-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6867816/
  46. www.sciencedirect.com www.sciencedirect.com
    Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons
    1
    1. scibot 03 Sep 2020
      Cat#52047 Addgene

      DOI: 10.1016/j.molcel.2020.01.020

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1097276520300411
  47. Jan 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
    1
    1. scibot 13 Jan 2020
      plasmid_52047

      DOI: 10.1016/j.molcel.2018.11.028

      Resource: RRID:Addgene_52047

      Curator: @Naa003

      SciCrunch record: plasmid_52047

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      RRID:Addgene_52047 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276518309985