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Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xgen.2025.100982
  
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cell.com/cell-genomics/abstract/S2666-979X(25)00238-1
Aug 2025
rupress.org rupress.org

Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity

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1. scibot 27 Aug 2025
  
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  DOI: 10.1084/jem.20242360
  
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rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

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1. scibot 27 Aug 2025
  
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  plasmid_52962
  
  DOI: 10.1038/s41467-025-62486-3
  
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nature.com/articles/s41467-025-62486-3
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Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation

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1. scibot 13 Aug 2025
  
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  plasmid_52962
  
  DOI: 10.1016/j.cels.2025.101346
  
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cell.com/cell-systems/abstract/S2405-4712(25)00179-6
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The RNA-binding protein RRP1 brakes macrophage one-carbon metabolism to suppress autoinflammation

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1. scibot 11 Aug 2025
  
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  DOI: 10.1038/s41467-025-62173-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12297237/
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Production of SARS-CoV-2 virus-like particles as a vaccine candidate in stable cell lines through inducible E and M protein expression

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1. scibot 11 Aug 2025
  
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  plasmid_52962
  
  DOI: 10.1186/s12896-025-01016-x
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302831/
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Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma

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1. scibot 11 Aug 2025
  
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  plasmid_52962
  
  DOI: 10.1101/2025.06.18.660431
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12262309/
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Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma

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1. scibot 11 Aug 2025
  
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  DOI: 10.1038/s41598-025-12192-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12276353/
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Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice

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1. scibot 11 Aug 2025
  
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  DOI: 10.1016/j.omtm.2025.101522
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12272419/
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A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic Transition

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1. scibot 11 Aug 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12311540/
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Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential

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1. scibot 10 Aug 2025
  
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  DOI: 10.1038/s41467-025-62668-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12331996/
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Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma

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1. scibot 07 Aug 2025
  
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  Addgene_52962
  
  DOI: 10.1158/1535-7163.MCT-24-0684
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12322148/
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 05 Aug 2025
  
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  DOI: 10.1002/1878-0261.70080
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70080
Jul 2025
www.biorxiv.org www.biorxiv.org

Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication

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1. scibot 30 Jul 2025
  
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  plasmid_52962
  
  DOI: 10.1101/2025.07.21.666025
  
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biorxiv.org/content/10.1101/2025.07.21.666025v1
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Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer

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1. scibot 25 Jul 2025
  
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  DOI: 10.1126/sciadv.adu0847
  
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science.org/doi/10.1126/sciadv.adu0847
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HIF-independent oxygen sensing via KDM6A regulates ferroptosis

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.molcel.2025.07.001
  
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sciencedirect.com/science/article/pii/S1097276525005805
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MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD

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1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113149
  
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52.53.155.43/383127a3ba30f18153ba559aaeac9e14b54b55e6/1-s2.0-S2589004225014105-main-html.html
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DNA demethylating agents suppress preclinical models of synovial sarcoma

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1. scibot 20 Jul 2025
  
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  52962
  
  DOI: 10.1172/JCI190855
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12208545/
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Targeting the Dependence on PIK3C3-mTORC1 Signaling in Dormancy-Prone Breast Cancer Cells Blunts Metastasis Initiation

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1. scibot 20 Jul 2025
  
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  DOI: 10.1158/0008-5472.CAN-23-2654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12167933/
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HVJ-E links Apolipoprotein d to antitumor effects

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1. scibot 20 Jul 2025
  
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  DOI: 10.1136/jitc-2024-011442
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12182123/
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A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease

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1. scibot 20 Jul 2025
  
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  DOI: 10.1093/nar/gkaf535
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12204706/
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NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication

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1. scibot 20 Jul 2025
  
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  DOI: 10.1093/gpbjnl/qzaf008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12233092/
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NINJ1 regulates plasma membrane fragility under mechanical strain

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1. scibot 20 Jul 2025
  
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  DOI: 10.1038/s41586-025-09222-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12210241/
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Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

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1. scibot 20 Jul 2025
  
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  DOI: 10.1038/s41467-025-60649-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12216638/
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A Versatile Reporter Platform for Evaluating HDR- and NHEJ-Based Genome Editing in Airway Epithelial Cell Cultures Using an rAAV Vector

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1. scibot 20 Jul 2025
  
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  plasmid_52962
  
  DOI: 10.3390/v17060821
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12197413/
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Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome

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1. scibot 20 Jul 2025
  
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  Plasmid_52962
  
  DOI: 10.1038/s41467-025-61156-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12229668/
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Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

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1. scibot 20 Jul 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.xgen.2025.100876
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12230241/
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The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA

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1. scibot 20 Jul 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.jbc.2025.110316
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12268640/
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The dual‐coding gene SLC35A4 protects against oxidative stress

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1. scibot 20 Jul 2025
  
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  Addgene_52962
  
  DOI: 10.1002/pro.70197
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12183330/
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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells

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1. scibot 19 Jul 2025
  
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  Addgene Cat#52962
  
  DOI: 10.1016/j.isci.2024.111399
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11647120/
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Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

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1. scibot 17 Jul 2025
  
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  Addgene_52
  
  DOI: 10.1186/s12964-025-02091-5
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11841277/
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An alternate receptor for adeno-associated viruses

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.026
  
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sciencedirect.com/science/article/pii/S0092867425006920
Jun 2025
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High-content image-based pooled screens reveal regulators of synaptogenesis

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1. scibot 25 Jun 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.celrep.2025.115889
  
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sciencedirect.com/science/article/pii/S2211124725006606
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 17 Jun 2025
  
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  DOI: 10.1158/2159-8290.cd-24-1904
  
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52.53.155.43/fedd6ccff8c0b6494dbe8595a0c800e33e0860f7/PDF-html.html
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In vivo CRISPR activation screen identifies acyl-CoA–binding protein as a driver of bone metastasis

1
1. scibot 15 Jun 2025
  
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  Addgene, 52962
  
  DOI: 10.1126/scitranslmed.ado7225
  
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science.org/doi/10.1126/scitranslmed.ado7225
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Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells

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1. scibot 15 Jun 2025
  
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  DOI: 10.1073/pnas.2418525122
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12107159/
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Systemic genome-epigenome analysis captures a lineage-specific super-enhancer for MYB in gastrointestinal adenocarcinoma

1
1. scibot 15 Jun 2025
  
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  52962
  
  DOI: 10.1038/s44320-025-00098-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12130324/
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Elevated nonhomologous end-joining by AATF enables efficient DNA damage repair and therapeutic resistance in glioblastoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12120020/
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Ferroptosis-activating metabolite acrolein antagonizes necroptosis and anti-cancer therapeutics

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WNK1 signalling regulates amino acid transport and mTORC1 activity to sustain acute myeloid leukaemia growth

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Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

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Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

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Resistance Signatures Manifested in Early Drug Response in Cancer and Across Species

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Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12

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Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer

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Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

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PDF-html.html

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CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation

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The genetic interaction map of the human solute carrier superfamily

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pmc.ncbi.nlm.nih.gov/articles/PMC12130552/
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APOBEC3 Activity Promotes the Survival and Evolution of Drug-Tolerant Persister Cells during EGFR Inhibitor Resistance in Lung Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12093302/
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A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

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Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells

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pmc.ncbi.nlm.nih.gov/articles/PMC12079664/
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Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
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Muscleblind-like proteins are novel modulators of the tumor-immune microenvironment

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pmc.ncbi.nlm.nih.gov/articles/PMC12043120/
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Innovative evaluation of selinexor and JQ1 synergy in leukemia therapy via C-MYC inhibition

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pmc.ncbi.nlm.nih.gov/articles/PMC12063270/
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Perturb-tracing enables high-content screening of multi-scale 3D genome regulators

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mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery

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1-s2.0-S2589004225006480-main-html.html

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pmc.ncbi.nlm.nih.gov/articles/PMC12063144/
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Targeted inhibition of PDGFRA with avapritinib, markedly enhances lenvatinib efficacy in hepatocellular carcinoma in vitro and in vivo: clinical implications

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pmc.ncbi.nlm.nih.gov/articles/PMC12057143/
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Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3-LPL Axis

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pmc.ncbi.nlm.nih.gov/articles/PMC12079391/
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The regulatory architecture of the primed pluripotent cell state

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Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12003641/
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Targeted demethylation of the EphA7 promoter inhibits tumorigenesis via the SP1/DNMT1 and PI3K/AKT axes and improves the response to multiple therapies in cervical cancer

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Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

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FEBS Press

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Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation

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Depletion of tumor-derived CXCL5 improves T cell infiltration and anti-PD-1 therapy response in an obese model of pancreatic cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11931939/
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Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages

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pmc.ncbi.nlm.nih.gov/articles/PMC11939036/
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Highly parallel profiling of the activities and specificities of Cas12a variants in human cells

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pmc.ncbi.nlm.nih.gov/articles/PMC11953374/
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CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance

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pmc.ncbi.nlm.nih.gov/articles/PMC11959757/
Mar 2025
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CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia

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pmc.ncbi.nlm.nih.gov/articles/PMC11905140/
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PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway

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pmc.ncbi.nlm.nih.gov/articles/PMC11921657/
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Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia

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  DOI: 10.1126/sciadv.ads8351
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
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Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to Kif18a Inhibition

1
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  52962
  
  DOI: 10.1101/2025.02.19.638911
  
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Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O‐Glycosylation

1
1. scibot 23 Mar 2025
  
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  Addgene_52962
  
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Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

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  plasmid_52962
  
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Onvansertib and Navitoclax Combination as a New Therapeutic Option for Mucinous Ovarian Carcinoma

1
1. scibot 11 Mar 2025
  
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  DOI: 10.3390/ijms26020472
  
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Recognition of MR1-antigen complexes by TCR Vγ9Vδ2

1
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  DOI: 10.3389/fimmu.2025.1519128
  
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Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status

1
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  DOI: 10.1186/s13046-025-03345-3
  
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Nuclear stiffness through lamin A/C overexpression differentially modulates chromosomal instability biomarkers

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Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid

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1-s2.0-S2352345X25000268-main-html.html

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  DOI: 10.1016/j.jcmgh.2025.101485
  
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

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Combinatorial mapping of E3 ubiquitin ligases to their target substrates

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CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production

1
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Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma

1
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  DOI: 10.1158/2643-3230.BCD-24-0020
  
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aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
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MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK

1
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  DOI: 10.1158/2326-6066.CIR-24-0110
  
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aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
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Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers

1
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  DOI: 10.1126/sciadv.adq3802
  
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Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer

1
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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

1
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  plasmid_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11788431/
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The Hippo pathway promotes platinum-based chemotherapy by inhibiting MTF1-dependent heavy metal response

1
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SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

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  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
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Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization

1
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  DOI: 10.1038/s44319-024-00357-6
  
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MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)

1
1. scibot 13 Feb 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1158/1078-0432.CCR-24-1750
  
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aacrjournals.org/clincancerres/article/30/22/5154/749570/MEK-Inhibitors-Lead-to-PDGFR-Pathway-Upregulation
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

7
1. scibot 07 Feb 2025
  
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  52962
  
  DOI: 10.1016/j.isci.2024.111444
  
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2. scibot 06 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 05 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 04 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 03 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 02 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 01 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Tubular ER structures shaped by ER-phagy receptors engage in stress-induced Golgi bypass

1
1. scibot 07 Feb 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.devcel.2025.01.011
  
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sciencedirect.com/science/article/pii/S1534580725000310
Jan 2025
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High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects

1
1. scibot 31 Jan 2025
  
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  RRID: Addgene_52962
  
  DOI: 10.1158/2326-6066.CIR-22-0815
  
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aacrjournals.org/cancerimmunolres/article/11/7/895/727496/High-Expression-of-MHC-Class-I-Overcomes-Cancer
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

31
1. scibot 31 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 29 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 28 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 27 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 26 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 25 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
8. scibot 24 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
9. scibot 23 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
10. scibot 22 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
11. scibot 21 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
12. scibot 20 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
13. scibot 19 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
14. scibot 18 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
15. scibot 17 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
16. scibot 16 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
17. scibot 15 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
18. scibot 14 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
19. scibot 13 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
20. scibot 12 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
21. scibot 11 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
22. scibot 10 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
23. scibot 09 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
24. scibot 08 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
25. scibot 07 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
26. scibot 06 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
27. scibot 05 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
28. scibot 04 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
29. scibot 03 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
30. scibot 02 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
31. scibot 01 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

1
1. scibot 30 Jan 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.xcrm.2025.101928
  
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SLC35A2 gene product modulates paramyxovirus fusion events during infection

1
1. scibot 27 Jan 2025
  
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  DOI: 10.1371/journal.ppat.1012531
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11756793/
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The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration

1
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  DOI: 10.1038/s41598-024-83468-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
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In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma

1
1. scibot 27 Jan 2025
  
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  plasmid_52962
  
  DOI: 10.1038/s41698-024-00792-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11723958/
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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

1
1. scibot 17 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.xcrm.2024.101913
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
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The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells

1
1. scibot 07 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.chembiol.2024.11.009
  
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sciencedirect.com/science/article/pii/S2451945624004896
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Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents

1
1. scibot 04 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1038/s41598-024-80834-z
  
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nature.com/articles/s41598-024-80834-z
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Identification of modulators of the ALT pathway through a native FISH-based optical screen

1
1. scibot 03 Jan 2025
  
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  Addgene52962
  
  DOI: 10.1016/j.celrep.2024.115114
  
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sciencedirect.com/science/article/pii/S2211124724014657
Dec 2024
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Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

4
1. scibot 31 Dec 2024
  
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  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Dec 2024
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 29 Dec 2024
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 28 Dec 2024
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1

1
1. scibot 29 Dec 2024
  
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  DOI: 10.1002/advs.202404620
  
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202404620
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EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations

1
1. scibot 28 Dec 2024
  
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  52962
  
  DOI: 10.1002/jev2.70017
  
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Targeting ketone body metabolism in mitigating gemcitabine resistance

1
1. scibot 27 Dec 2024
  
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  52962
  
  DOI: 10.1172/jci.insight.177840
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11665555/
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Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

1
1. scibot 27 Dec 2024
  
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  52962
  
  DOI: 10.1038/s41586-024-08224-z
  
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GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens

1
1. scibot 27 Dec 2024
  
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  Addgene_52962
  
  DOI: 10.1371/journal.pone.0315923
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11654918/
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TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome

2
1. scibot 24 Dec 2024
  
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  AddgeneCat# 52962
  
  DOI: 10.1016/j.molcel.2024.11.007
  
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  DOI: 10.1016/j.molcel.2024.11.007
  
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The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells

1
1. scibot 24 Dec 2024
  
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  AddgeneCat#52962
  
  DOI: 10.1016/j.immuni.2024.11.019
  
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3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

1
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  DOI: 10.1016/j.molcel.2024.11.040
  
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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells

1
1. scibot 14 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.isci.2024.111399
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11647120/
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Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

1
1. scibot 13 Dec 2024
  
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  DOI: 10.1038/s44321-024-00161-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
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Control of cell proliferation by memories of mitosis

1
1. scibot 11 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1126/science.add9528
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11621110/
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Mitochondrial elongation impairs breast cancer metastasis

1
1. scibot 07 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1126/sciadv.adm8212
  
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science.org/doi/10.1126/sciadv.adm8212
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Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

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  cat. no. 52962, Addgene
  
  DOI: 10.1038/s42255-024-01166-w
  
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genomebiology.biomedcentral.com genomebiology.biomedcentral.com

Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors

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genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
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Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation

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  Addgene_52962
  
  DOI: 10.1101/2024.09.26.615177
  
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Mitochondrial elongation impairs breast cancer metastasis

1
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  RRID:Addgene_52962
  
  DOI: 10.1126/sciadv.adm8212
  
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Sep 2024
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Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction

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  DOI: 10.1126/sciadv.adl5638
  
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Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction

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Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

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The Aryl Hydrocarbon Receptor Controls IFNγ-Induced Immune Checkpoints PD-L1 and IDO via the JAK/STAT Pathway in Lung Adenocarcinoma

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CRISPR screen of venetoclax response-associated genes identifies transcription factor ZNF740 as a key functional regulator

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Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization

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Mechanism for controlled assembly of transcriptional condensates by Aire

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CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing

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USP44 Overexpression Drives a MYC-Like Gene Expression Program in Neuroblastoma through Epigenetic Reprogramming

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The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation

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SLC35A2 modulates paramyxovirus fusion events during infection

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BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A

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Saturation mutagenesis-reinforced functional assays for disease-related genes

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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

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Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

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PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma

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The Proteasome and Cul3-Dependent Protein Ubiquitination Is Required for Gli Protein-Mediated Activation of Gene Expression in the Hedgehog Pathway

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GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer

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Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer

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GeneRaMeN enables integration, comparison, and meta-analysis of multiple ranked gene lists to identify consensus, unique, and correlated genes

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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression

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Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

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  Addgene_52
  
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CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines

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IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling

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Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology

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MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer

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Shifts in receptors during submergence of an encephalitic arbovirus

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Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection

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Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma

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CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma

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Specific multivalent molecules boost CRISPR-mediated transcriptional activation

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Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

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ncbi.nlm.nih.gov/pmc/articles/PMC11326134/
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INAUGURAL ARTICLE by a Recently Elected Academy Member:Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers

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CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism

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  Addgene Cat#52962
  
  DOI: 10.1016/j.celrep.2024.114662
  
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YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response

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The SW480 cell line as a model of resident and migrating colon cancer stem cells

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