199 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets
    1
    1. scibot 04 Jul 2024
      RRID:Addgene_52962

      DOI: 10.1136/jitc-2024-009410

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    ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E
    1
    1. scibot 30 Jun 2024
      52962

      DOI: 10.3390/v16060898

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    ncbi.nlm.nih.gov/pmc/articles/PMC11209299/
  5. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
    1
    1. scibot 30 Jun 2024
      Addgene_52962

      DOI: 10.1016/j.isci.2024.110131

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    cell.com/iscience/abstract/S2589-0042(24)01356-7
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans
    1
    1. scibot 21 Jun 2024
      52962

      DOI: 10.1101/2024.05.23.595417

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    ncbi.nlm.nih.gov/pmc/articles/PMC11142209/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential
    1
    1. scibot 21 Jun 2024
      52962

      DOI: 10.21203/rs.3.rs-4462139/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11160910/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation
    1
    1. scibot 20 Jun 2024
      Addgene_52962

      DOI: 10.1126/sciimmunol.adi1023

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    ncbi.nlm.nih.gov/pmc/articles/PMC11182672/
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation
    1
    1. scibot 15 Jun 2024
      Addgene_52962

      DOI: 10.1186/s13075-024-03350-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11165854/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
    1
    1. scibot 10 Jun 2024
      Addgene_52962

      DOI: 10.1038/s44320-024-00032-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148184/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells
    2
    1. scibot 07 Jun 2024
      52962

      DOI: 10.1126/sciadv.adj1564

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    2. scibot 07 Jun 2024
      52962

      DOI: 10.1126/sciadv.adj1564

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    ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
  12. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
    1
    1. scibot 06 Jun 2024
      AddgeneCat# 52962

      DOI: 10.1016/j.xcrm.2024.101592

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      RRID:Addgene_52962 DOI:10.1016/j.xcrm.2024.101592
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    sciencedirect.com/science/article/pii/S2666379124002842
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta
    1
    1. scibot 03 Jun 2024
      52962

      DOI: 10.1016/j.isci.2024.109921

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    ncbi.nlm.nih.gov/pmc/articles/PMC11133927/
  14. May 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes
    1
    1. scibot 12 May 2024
      Addgene_52962

      DOI: 10.1128/mbio.03429-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC11078001/
  16. www.sciencedirect.com www.sciencedirect.com
    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
      Addgene Cat# 52962

      DOI: 10.1016/j.celrep.2024.114211

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    sciencedirect.com/science/article/pii/S2211124724005394
  17. www.nature.com www.nature.com
    De novo generation of multi-target compounds using deep generative chemistry
    1
    1. scibot 08 May 2024
      RRID:Addgene_52962

      DOI: 10.1038/s41467-024-47120-y

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    nature.com/articles/s41467-024-47120-y
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
    1
    1. scibot 05 May 2024
      plasmid_52962

      DOI: 10.1038/s12276-024-01205-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC11058268/
  19. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 03 May 2024
      RRID:Addgene_52962

      DOI: 10.7554/eLife.90683

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    elifesciences.org/articles/90683
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pooled multicolour tagging for visualizing subcellular protein dynamics
    1
    1. scibot 03 May 2024
      RRID:Addgene_52962

      DOI: 10.1038/s41556-024-01407-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11098740/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Correlates of Venetoclax-Based Combination Sensitivities to Augment Acute Myeloid Leukemia Therapy
    1
    1. scibot 02 May 2024
      Addgene, #52962

      DOI: 10.1158/2643-3230.BCD-23-0014

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618724/
  22. Apr 2024
  23. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
    1
    1. scibot 30 Apr 2024
      Addgene: 52962

      DOI: 10.1016/j.molcel.2024.04.006

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    sciencedirect.com/science/article/pii/S1097276524002843
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MYADM binds human parechovirus 1 and is essential for viral entry
    1
    1. scibot 30 Apr 2024
      52962

      DOI: 10.1038/s41467-024-47825-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC11043367/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency
    1
    1. scibot 30 Apr 2024
      Addgene_52962

      DOI: 10.21203/rs.3.rs-3995251/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030533/
  26. www.sciencedirect.com www.sciencedirect.com
    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
    1
    1. scibot 24 Apr 2024
      AddgeneCat# 52962

      DOI: 10.1016/j.cell.2024.03.039

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    sciencedirect.com/science/article/pii/S0092867424003556
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma
    1
    1. scibot 24 Apr 2024
      plasmid_52962

      DOI: 10.1038/s41467-024-47771-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11039739/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERG activates a stem-like proliferation-differentiation program in prostate epithelial cells with mixed basal-luminal identity
    2
    1. scibot 23 Apr 2024
      52962

      DOI: 10.1101/2023.05.15.540839

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    2. scibot 23 Apr 2024
      plasmid_52962

      DOI: 10.1101/2023.05.15.540839

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    ncbi.nlm.nih.gov/pmc/articles/PMC10996491/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity
    1
    1. scibot 23 Apr 2024
      Addgene_52962

      DOI: 10.1073/pnas.2316447121

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    ncbi.nlm.nih.gov/pmc/articles/PMC11009675/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia
    1
    1. scibot 23 Apr 2024
      https://www.addgene.org/52962/

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    ncbi.nlm.nih.gov/pmc/articles/PMC11014662/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers
    1
    1. scibot 23 Apr 2024
      52962

      DOI: 10.1038/s41419-024-06654-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11024179/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
    1
    1. scibot 15 Apr 2024
      52962

      DOI: 10.1038/s41467-024-46602-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens
    1
    1. scibot 15 Apr 2024
      52962

      DOI: 10.1038/s41594-024-01211-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948361/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14
    1
    1. scibot 15 Apr 2024
      Addgene_52962

      DOI: 10.1101/2024.03.07.583953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942435/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A fast-acting lipid checkpoint in G1 prevents mitotic defects
    1
    1. scibot 15 Apr 2024
      plasmid_52962

      DOI: 10.1038/s41467-024-46696-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10948896/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the insulin receptor by insulin-like growth factor 2
    1
    1. scibot 15 Apr 2024
      Addgene_52962

      DOI: 10.1038/s41467-024-46990-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10960814/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial injury induced by a Salmonella genotoxin triggers the proinflammatory senescence-associated secretory phenotype
    1
    1. scibot 14 Apr 2024
      52962

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    ncbi.nlm.nih.gov/pmc/articles/PMC10981749/
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma
    1
    1. scibot 05 Apr 2024
      RRID:Addgene_52962

      DOI: 10.1002/jcb.30542

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    onlinelibrary.wiley.com/doi/10.1002/jcb.30542
  39. www.sciencedirect.com www.sciencedirect.com
    Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
    1
    1. scibot 04 Apr 2024
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2024.114041

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    sciencedirect.com/science/article/pii/S2211124724003693
  40. Mar 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 targeting of passenger single nucleotide variants in haploinsufficient or essential genes expands cancer therapy prospects
    1
    1. scibot 31 Mar 2024
      52,962

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    ncbi.nlm.nih.gov/pmc/articles/PMC10978915/
  42. www.sciencedirect.com www.sciencedirect.com
    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
    1
    1. scibot 29 Mar 2024
      Addgene52962

      DOI: 10.1016/j.crmeth.2024.100737

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    sciencedirect.com/science/article/pii/S2667237524000626
  43. www.sciencedirect.com www.sciencedirect.com
    A gut-derived hormone regulates cholesterol metabolism
    2
    1. scibot 19 Mar 2024
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2024.02.024

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    2. scibot 19 Mar 2024
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2024.02.024

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    sciencedirect.com/science/article/pii/S0092867424002265
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic determinants of micronucleus formation in vivo
    1
    1. scibot 17 Mar 2024
      52962

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    ncbi.nlm.nih.gov/pmc/articles/PMC10917660/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells
    1
    1. scibot 17 Mar 2024
      52962

      DOI: 10.1111/cas.16070

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    ncbi.nlm.nih.gov/pmc/articles/PMC10920982/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells
    1
    1. scibot 17 Mar 2024
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      DOI: 10.1101/2024.02.15.580539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10896345/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
    1
    1. scibot 16 Mar 2024
      Addgene_52962

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  48. link.springer.com link.springer.com
    Functionally-instructed modifiers of response to ATR inhibition in experimental glioma
    1
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      RRID:Addgene_52962

      DOI: 10.1186/s13046-024-02995-z

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  49. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
    1
    1. scibot 08 Mar 2024
      Plasmid #52962

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  50. www.sciencedirect.com www.sciencedirect.com
    In vivo CRISPR screening directly targeting testicular cells
    1
    1. scibot 06 Mar 2024
      Addgene: #52962

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracting, filtering and simulating cellular barcodes using CellBarcode tools
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  52. Feb 2024
  53. www.sciencedirect.com www.sciencedirect.com
    A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis
    1
    1. scibot 29 Feb 2024
      AddgeneCat#52962

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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1
    1
    1. scibot 13 Feb 2024
      lentiCas9-Blast

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  57. www.biorxiv.org www.biorxiv.org
    Saturation resistance profiling of EGFR variants against tyrosine kinase inhibitors using prime editing
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy
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    1. scibot 08 Feb 2024
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  59. www.sciencedirect.com www.sciencedirect.com
    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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      AddgeneCat# 52962

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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9
    1
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo
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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
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  64. www.sciencedirect.com www.sciencedirect.com
    Two-step evolution of HIV-1 budding system leading to pandemic in the human population
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  65. Jan 2024
  66. www-sciencedirect-com.proxy.uchicago.edu www-sciencedirect-com.proxy.uchicago.edu
    Cell surface RNAs control neutrophil recruitment
    1
    1. scibot 23 Jan 2024
      AddgeneCat# 52962

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  67. www.nature.com www.nature.com
    Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia
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    1. scibot 18 Jan 2024
      RRID:Addgene_52962

      DOI: 10.1038/s41598-024-52020-8

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  68. www.sciencedirect.com www.sciencedirect.com
    Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
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      RRID:Addgene_52962

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  69. Dec 2023
  70. www.sciencedirect.com www.sciencedirect.com
    EGFR-activated myofibroblasts promote metastasis of pancreatic cancer
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    1. scibot 29 Dec 2023
      Cat# 52962, Addgene

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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      RRID:Addgene_52962

      DOI: 10.1158/0008-5472.CAN-22-2948

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  72. www.sciencedirect.com www.sciencedirect.com
    Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
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      RRID:Addgene_52962

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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
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      DOI: 10.7554/eLife.87098

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  74. Nov 2023
  75. www.sciencedirect.com www.sciencedirect.com
    Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma
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  76. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The promiscuous development of an unconventional Qa1b-restricted T cell population
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      DOI: 10.3389/fimmu.2023.1250316

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  78. Oct 2023
  79. www.biorxiv.org www.biorxiv.org
    Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level
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    biorxiv.org/content/10.1101/2023.10.16.562592v1
  80. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ADAR1 Biology Can Hinder Effective Antiviral RNA Interference
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      RRID:Addgene_52962

      DOI: 10.1128/jvi.00245-23

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  82. Sep 2023
  83. www.nature.com www.nature.com
    Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia
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  84. Aug 2023
  85. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
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  87. Jul 2023
  88. www.nature.com www.nature.com
    Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities
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      DOI: 10.1038/s41594-023-01041-4

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  89. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coding and non-coding elements comprise a regulatory network controlling transcription in Kaposi’s sarcoma-associated herpesvirus
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer
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  92. www.sciencedirect.com www.sciencedirect.com
    Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
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  93. 52.53.155.43 52.53.155.43
    cir-22-0815-html.html
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      DOI: 10.1158/2326-6066.CIR-22-0815

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  94. Jun 2023
  95. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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      DOI: 10.1016/j.cell.2023.05.047

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  96. www.sciencedirect.com www.sciencedirect.com
    An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets
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  97. www.biorxiv.org www.biorxiv.org
    Transcriptional landscape of DTP-DTEP transition reveals DUSP6 as a driver of HER2 inhibitor tolerance via Neuregulin/HER3 axis
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      plasmid_52962

      DOI: 10.1101/2023.06.14.544493

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    biorxiv.org/content/10.1101/2023.06.14.544493v1
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IKKβ primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network
    1
    1. scibot 14 Jun 2023
      RRID:Addgene_52962

      DOI: 10.1016/j.immuni.2022.10.021

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    ncbi.nlm.nih.gov/pmc/articles/PMC7614333/
  99. dx.doi.org dx.doi.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
    1
    1. scibot 10 Jun 2023
      RRID:Addgene_52962

      DOI: 10.1158/2159-8290.CD-22-0825

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    dx.doi.org/10.1158/2159-8290.CD-22-0825
  100. aacrjournals.org aacrjournals.org
    RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-1549

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    aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
  101. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
    1
    1. scibot 02 Jun 2023
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    sciencedirect.com/science/article/pii/S0092867423005226
  102. May 2023
  103. www.biorxiv.org www.biorxiv.org
    Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia
    1
    1. scibot 25 May 2023
      RRID:Addgene_52962

      DOI: 10.1101/2023.05.18.541265

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    biorxiv.org/content/10.1101/2023.05.18.541265v1
  104. www.pnas.org www.pnas.org
    A genome-wide optical pooled screen reveals regulators of cellular antiviral responses
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    pnas.org/doi/abs/10.1073/pnas.2210623120
  105. www.sciencedirect.com www.sciencedirect.com
    Amelioration of SARS-CoV-2 infection by ANO6 phospholipid scramblase inhibition
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    1. scibot 05 May 2023
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    sciencedirect.com/science/article/pii/S2211124722009238
  106. Apr 2023
  107. www.sciencedirect.com www.sciencedirect.com
    IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling
    1
    1. scibot 22 Apr 2023
      plasmid_52962

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    sciencedirect.com/science/article/pii/S0898656823000980
  108. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    1. scibot 21 Apr 2023
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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  109. www.sciencedirect.com www.sciencedirect.com
    Proteomic discovery of chemical probes that perturb protein complexes in human cells
    1
    1. scibot 21 Apr 2023
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    sciencedirect.com/science/article/pii/S1097276523002393
  110. www.sciencedirect.com www.sciencedirect.com
    Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens
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    sciencedirect.com/science/article/pii/S1097276523002034
  111. www.biorxiv.org www.biorxiv.org
    Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome
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    1. scibot 05 Apr 2023
      RRID:Addgene_52962

      DOI: 10.1101/2023.02.13.528260

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    biorxiv.org/content/10.1101/2023.02.13.528260v1
  112. Mar 2023
  113. aacrjournals.org aacrjournals.org
    Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer
    1
    1. scibot 24 Mar 2023
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    aacrjournals.org/cancerdiscovery/article/11/12/3214/674718/Rlf-Mycl-Gene-Fusion-Drives-Tumorigenesis-and
  114. www.nature.com www.nature.com
    FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
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    1. scibot 23 Mar 2023
      plasmid_52962

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    nature.com/articles/s41586-021-04144-4
  115. www.nature.com www.nature.com
    The protective role of conjunctival goblet cell mucin sialylation
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      RRID:Addgene_52962

      DOI: 10.1038/s41467-023-37101-y

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    nature.com/articles/s41467-023-37101-y
  116. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    1. scibot 11 Mar 2023
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    sciencedirect.com/science/article/pii/S2666979X23000368
  117. Feb 2023
  118. www.sciencedirect.com www.sciencedirect.com
    An adverse tumor-protective effect of IDO1 inhibition
    1
    1. scibot 23 Feb 2023
      RRID:Addgene_52962

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    sciencedirect.com/science/article/pii/S2666379123000332
  119. 52.53.155.43 52.53.155.43
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    1. scibot 11 Feb 2023
      RRID:Addgene_52962

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    52.53.155.43/67ba005538cc0cc62d34c50598f914c3efc88864/91-html.html
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening reveals a dependency on ribosome recycling for efficient SARS-CoV-2 programmed ribosomal frameshifting and viral replication
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      RRID:Addgene_52962

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    ncbi.nlm.nih.gov/pmc/articles/PMC9884621/
  121. Jan 2023
  122. www.sciencedirect.com www.sciencedirect.com
    Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia
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    1. scibot 24 Jan 2023
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2023.112027

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    sciencedirect.com/science/article/pii/S2211124723000384
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of β2 microglobulin, the product of B2M gene, as a Host Factor for Vaccinia Virus Infection by Genome-Wide CRISPR genetic screens
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    1. scibot 11 Jan 2023
      RRID:Addgene_52962

      DOI: 10.1371/journal.ppat.1010800

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    ncbi.nlm.nih.gov/pmc/articles/PMC9829182/
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Bak1 alleviates microglial necroptosis and neuroinflammation after experimental subarachnoid hemorrhage
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    1. scibot 10 Jan 2023
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      DOI: 10.1111/jnc.15751

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15751
  125. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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      DOI: 10.1016/j.stem.2022.12.006

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    sciencedirect.com/science/article/pii/S1934590922004908
  126. Dec 2022
  127. www.sciencedirect.com www.sciencedirect.com
    KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
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    1. scibot 17 Dec 2022
      Addgene_52962

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    sciencedirect.com/science/article/pii/S1535610822005621
  128. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
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      DOI: 10.15252/emmm.202115631

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  129. Nov 2022
  130. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    1. scibot 24 Nov 2022
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    sciencedirect.com/science/article/pii/S2211124722015492
  131. www.pnas.org www.pnas.org
    Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
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    1. scibot 17 Nov 2022
      RRID:Addgene_52962

      DOI: 10.1073/pnas.2122188119

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  132. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
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      Plasmid_52962

      DOI: 10.1016/j.molcel.2022.10.005

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  133. www.sciencedirect.com www.sciencedirect.com
    Arid1a loss potentiates pancreatic β-cell regeneration through activation of EGF signaling
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  134. Sep 2022
  135. www.nature.com www.nature.com
    Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3
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      RRID:Addgene_52962

      DOI: 10.1038/s41467-022-32758-3

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  136. Aug 2022
  137. www.sciencedirect.com www.sciencedirect.com
    ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain
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    sciencedirect.com/science/article/pii/S2211124722010865
  138. www.sciencedirect.com www.sciencedirect.com
    Cancer genes disfavoring T cell immunity identified via integrated systems approach
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    1. scibot 06 Aug 2022
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  139. Jul 2022
  140. www.jneurosci.org www.jneurosci.org
    Modulating the excitability of olfactory output neurons affects whole-body metabolism
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      plasmid_52962

      DOI: 10.1523/JNEUROSCI.0190-22.2022

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    jneurosci.org/content/42/30/5966
  141. Jun 2022
  142. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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      RRID:Addgene_52962

      DOI: 10.15252/embr.202154133

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  143. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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      RRID:Addgene_52962

      DOI: 10.1016/j.xcrm.2022.100655

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    sciencedirect.com/science/article/pii/S2666379122001872
  144. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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      RRID:Addgene_52962

      DOI: 10.1007/s10120-022-01307-8

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    link.springer.com/article/10.1007/s10120-022-01307-8
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
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      RRID:Addgene_52962

      DOI: 10.1158/2326-6066.CIR-21-0754

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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  146. May 2022
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
    1
    1. scibot 18 May 2022
      plasmid_52962

      DOI: 10.7554/eLife.76541

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    ncbi.nlm.nih.gov/pmc/articles/PMC9094746/
  148. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
    1
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      RRID:Addgene_52962

      DOI: 10.1158/2159-8290.CD-21-1006

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    aacrjournals.org/cancerdiscovery/article/12/5/1314/694563/Melanoma-Secreted-Amyloid-Beta-Suppresses
  149. Apr 2022
  150. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
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    1. scibot 07 Apr 2022
      AddgeneCat# 52962

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    sciencedirect.com/science/article/pii/S2211124722003898
  151. Mar 2022
  152. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 screening identifies the CYTH2 host gene as a potential therapeutic target of influenza viral infection
    1
    1. scibot 30 Mar 2022
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2022.110559

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    sciencedirect.com/science/article/pii/S2211124722003035
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry
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    1. scibot 26 Mar 2022
      plasmid_52962

      DOI: 10.7554/eLife.77444

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    ncbi.nlm.nih.gov/pmc/articles/PMC8942469/
  154. link.springer.com link.springer.com
    Partial p53 reactivation is sufficient to induce cancer regression
    1
    1. scibot 03 Mar 2022
      RRID:Addgene_52962

      DOI: 10.1186/s13046-022-02269-6

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    link.springer.com/article/10.1186/s13046-022-02269-6
  155. Feb 2022
  156. www.sciencedirect.com www.sciencedirect.com
    ZEB1-regulated lnc-Nr2f1 promotes the migration and invasion of lung adenocarcinoma cells
    1
    1. scibot 16 Feb 2022
      RRID:Addgene_52962

      DOI: 10.1016/j.canlet.2022.215601

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    sciencedirect.com/science/article/pii/S0304383522000763
  157. www.sciencedirect.com www.sciencedirect.com
    Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells
    2
    1. scibot 11 Feb 2022
      Addgene 52962

      DOI: 10.1016/j.chembiol.2022.01.002

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    2. scibot 11 Feb 2022
      Addgene 52962

      DOI: 10.1016/j.chembiol.2022.01.002

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    sciencedirect.com/science/article/pii/S2451945622000022
  158. Jan 2022
  159. www.nature.com www.nature.com
    Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins
    1
    1. scibot 15 Jan 2022
      RRID:Addgene_52962

      DOI: 10.1038/s42003-021-02953-x

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    nature.com/articles/s42003-021-02953-x
  160. www.sciencedirect.com www.sciencedirect.com
    ACE2 can act as the secondary receptor in the FcγR-dependent ADE of SARS-CoV-2 infection
    1
    1. scibot 14 Jan 2022
      AddgeneCAT#52962

      DOI: 10.1016/j.isci.2021.103720

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    sciencedirect.com/science/article/pii/S2589004221016904
  161. Sep 2021
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog—GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_52962

      DOI: 10.3390/cancers13164227

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    ncbi.nlm.nih.gov/pmc/articles/PMC8394935/
  163. Aug 2021
  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network
    1
    1. scibot 14 Aug 2021
      Plasmid_52962

      DOI: 10.1016/j.molcel.2019.03.025

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    ncbi.nlm.nih.gov/pmc/articles/PMC6671628/
  165. www.sciencedirect.com www.sciencedirect.com
    Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance
    1
    1. scibot 11 Aug 2021
      plasmid_52962

      DOI: 10.1016/j.ccell.2017.10.008

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    sciencedirect.com/science/article/pii/S1535610817304610
  166. www.nature.com www.nature.com
    Untitled document
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    1. scibot 11 Aug 2021
      plasmid_52962

      DOI: 10.1038/s41598-018-37940-6

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    nature.com/articles/s41598-018-37940-6
  167. www.sciencedirect.com www.sciencedirect.com
    Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution
    2
    1. scibot 05 Aug 2021
      RRID:Addgene_529

      DOI: 10.1016/j.celrep.2021.109460

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      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:Addgene_52962
    2. scibot 01 Aug 2021
      plasmid_52962

      DOI: 10.1016/j.celrep.2021.109460

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    sciencedirect.com/science/article/pii/S2211124721008834
  168. www.sciencedirect.com www.sciencedirect.com
    The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections
    1
    1. scibot 01 Aug 2021
      plasmid_52962

      DOI: 10.1016/j.celrep.2019.12.014

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    sciencedirect.com/science/article/pii/S221112471931664X
  169. Jul 2021
  170. www.sciencedirect.com www.sciencedirect.com
    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
    1
    1. scibot 29 Jul 2021
      RRID: Addgene_52962

      DOI: 10.1016/j.cell.2019.10.034

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    sciencedirect.com/science/article/pii/S0092867419312115
  171. elifesciences.org elifesciences.org
    CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors
    1
    1. scibot 28 Jul 2021
      RRID:Addgene_ 52962

      DOI: 10.7554/eLife.43653

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    elifesciences.org/articles/43653
  172. www.cell.com www.cell.com
    Untitled document
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    1. scibot 28 Jul 2021
      plasmid_52962

      DOI: 10.1016/j.ccell.2017.10.008

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    cell.com/cancer-cell/abstract/S1535-6108(17)30461-0
  173. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 27 Jul 2021
      RRID_Addgene_52962

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  174. www.sciencedirect.com www.sciencedirect.com
    HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV
    1
    1. scibot 14 Jul 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2021.109378

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    sciencedirect.com/science/article/pii/S2211124721007762
  175. Jun 2021
  176. www.sciencedirect.com www.sciencedirect.com
    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
    1
    1. scibot 30 Jun 2021
      plasmid_52962

      DOI: 10.1016/j.molcel.2021.06.020

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    sciencedirect.com/science/article/pii/S1097276521005001
  177. www.sciencedirect.com www.sciencedirect.com
    Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
    1
    1. scibot 25 Jun 2021
      52962

      DOI: 10.1016/j.cell.2021.05.038

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    sciencedirect.com/science/article/pii/S0092867421006905
  178. www.sciencedirect.com www.sciencedirect.com
    The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
    1
    1. scibot 25 Jun 2021
      Cat#52962

      DOI: 10.1016/j.ccell.2021.06.003

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    sciencedirect.com/science/article/pii/S1535610821002865
  179. May 2021
  180. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
    1
    1. scibot 14 May 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  181. www.sciencedirect.com www.sciencedirect.com
    Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation
    1
    1. scibot 09 May 2021
      Addgene_52962

      DOI: 10.1016/j.stem.2020.12.005

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    sciencedirect.com/science/article/pii/S1934590920305890
  182. www.sciencedirect.com www.sciencedirect.com
    RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins
    1
    1. scibot 07 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2020.06.023

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    sciencedirect.com/science/article/pii/S1097276520304251
  183. www.sciencedirect.com www.sciencedirect.com
    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
    1
    1. scibot 07 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2020.05.011

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    sciencedirect.com/science/article/pii/S1097276520303129
  184. www.sciencedirect.com www.sciencedirect.com
    A Weak Link with Actin Organizes Tight Junctions to Control Epithelial Permeability
    1
    1. scibot 05 May 2021
      Plasmid_52962

      DOI: 10.1016/j.devcel.2020.07.022

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    sciencedirect.com/science/article/pii/S1534580720305979
  185. www.sciencedirect.com www.sciencedirect.com
    Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane
    1
    1. scibot 03 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2021.02.025

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    sciencedirect.com/science/article/pii/S1097276521001350
  186. Apr 2021
  187. www.sciencedirect.com www.sciencedirect.com
    The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
    1
    1. scibot 30 Apr 2021
      Plasmid_52962

      DOI: 10.1016/j.cmet.2020.12.003

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    sciencedirect.com/science/article/pii/S1550413120306586
  188. www.sciencedirect.com www.sciencedirect.com
    Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
    1
    1. scibot 28 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.chom.2020.05.012

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    sciencedirect.com/science/article/pii/S1931312820302948
  189. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
    1
    1. scibot 27 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.cels.2020.08.010

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    sciencedirect.com/science/article/pii/S2405471220302945
  190. www.sciencedirect.com www.sciencedirect.com
    Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate
    1
    1. scibot 24 Apr 2021
      addgene_52962

      DOI: 10.1016/j.cell.2020.06.006

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    sciencedirect.com/science/article/pii/S0092867420306930
  191. www.nature.com www.nature.com
    CRL4 AMBRA1 is a master regulator of D-type cyclins
    1
    1. scibot 22 Apr 2021
      plasmid_52962

      DOI: 10.1038/s41586-021-03445-y

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      RRIDCUR:Validated RRID:Addgene_52962
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    nature.com/articles/s41586-021-03445-y
  192. www.sciencedirect.com www.sciencedirect.com
    Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
    1
    1. scibot 20 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.ccell.2020.06.006

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    sciencedirect.com/science/article/pii/S153561082030310X
  193. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      plasmid_52962

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  194. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.molcel.2021.03.034

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    sciencedirect.com/science/article/pii/S109727652100229X
  195. Mar 2021
  196. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
    1
    1. scibot 17 Mar 2021
      Plasmid_52962

      DOI: 10.1016/j.celrep.2021.108859

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    sciencedirect.com/science/article/pii/S221112472100173X
  197. Feb 2021
  198. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_52962

      DOI: 10.7554/eLife.60609

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    elifesciences.org/articles/60609
  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
    1
    1. scibot 26 Feb 2021
      plasmid_52962

      DOI: 10.1016/j.cell.2020.09.033

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    ncbi.nlm.nih.gov/pmc/articles/PMC7489987/
  200. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 24 Feb 2021
      Plasmid_52962

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  201. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  202. journals.plos.org journals.plos.org
    N-Glycans and sulfated glycosaminoglycans contribute to the action of diverse Tc toxins on mammalian cells
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52962

      DOI: 10.1371/journal.ppat.1009244

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    journals.plos.org/plospathogens/article
  203. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 23 Feb 2021
      RRID:_Addgene_52962

      DOI: 10.1016/j.ccell.2019.12.007

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      RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561081930577X
  204. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
    1
    1. scibot 11 Feb 2021
      Plasmid_52962

      DOI: 10.1016/j.ccell.2020.03.001

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    sciencedirect.com/science/article/pii/S153561082030101X
  205. Jan 2021
  206. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.chom.2020.12.009

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1931312820306715
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2020.12.006

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7796900/
  208. www.sciencedirect.com www.sciencedirect.com
    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
    1
    1. scibot 20 Jan 2021
      Addgene_52962

      DOI: 10.1016/j.xcrm.2020.100188

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2666379120302433
  209. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Plasmid_52962

      DOI: 10.1016/j.chom.2020.04.024

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S1931312820302511
  210. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.108532

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720315217
  211. Dec 2020
  212. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin’s lymphoma and testicular cancer cells
    1
    1. scibot 09 Dec 2020
      RRID:Addgene_52962

      DOI: 10.1038/s41419-020-03231-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC7705021/
  213. www.sciencedirect.com www.sciencedirect.com
    Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
    1
    1. scibot 07 Dec 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.108444

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124720314339
  214. Nov 2020
  215. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
    1
    1. scibot 18 Nov 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2020.09.014

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7737474/
  216. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
    2
    1. scibot 14 Nov 2020
      Addgene #52962

      DOI: 10.1016/j.celrep.2020.108371

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      SciCrunch record: RRID:Addgene_52962

      Curator comments: lentiCas9-Blast

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      RRID:Addgene_52962
    2. scibot 14 Nov 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108371

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      RRIDCUR:Validated RRID:Addgene_52962
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    pubmed.ncbi.nlm.nih.gov/33176151/
  217. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
    1
    1. scibot 12 Nov 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108341

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    sciencedirect.com/science/article/pii/S2211124720313309
  218. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
    1
    1. scibot 05 Nov 2020
      Lenti-Cas9-Blast

      DOI: 10.1016/j.cell.2020.10.028

      Resource: RRID:Addgene_52962

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      RRIDCUR:Missing RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S0092867420313921
  219. Oct 2020
  220. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM41B is a pan-flavivirus host factor
    1
    1. scibot 24 Oct 2020
      RRID:Addgene_52962

      DOI: 10.1101/2020.10.09.334128

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7553181/
  221. Sep 2020
  222. www.sciencedirect.com www.sciencedirect.com
    Kinetic Heterogeneity of Cancer Cell Fractional Killing
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.107845

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124720308263
  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1002/1878-0261.12753

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7463323/
  224. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.12.007

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561081930577X
  225. www.sciencedirect.com www.sciencedirect.com
    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
    1
    1. scibot 16 Sep 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.107860

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S221112472030841X
  226. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1093/nar/gkaa147

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7192610/
  227. www.sciencedirect.com www.sciencedirect.com
    The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks
    1
    1. scibot 05 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2019.12.067

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124719317243
  228. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses
    1
    1. scibot 04 Sep 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108080

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    pubmed.ncbi.nlm.nih.gov/32877684/
  229. Aug 2020
  230. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2020
      Addgene Plasmid #52962

      DOI: 10.1016/j.ccell.2019.12.002

      Resource: RRID:Addgene_52962

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    sciencedirect.com/science/article/pii/S1535610819305720
  231. Jan 2020
  232. www.nature.com www.nature.com
    α-Ketoglutarate links p53 to cell fate during tumour suppression
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1038/s41586-019-1577-5

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    nature.com/articles/s41586-019-1577-5
  233. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2019.06.014

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419306774
  234. www.sciencedirect.com www.sciencedirect.com
    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.09.005

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819304258
  235. www.embopress.org www.embopress.org
    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
    1
    1. scibot 13 Jan 2020
      plasmid_52962

      DOI: 10.15252/embr.201948235

      Resource: RRID:Addgene_52962

      Curator: @Naa003

      SciCrunch record: plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    embopress.org/doi/full/10.15252/embr.201948235
  236. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.05.013

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819302557
  237. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
    1
    1. scibot 13 Jan 2020
      Plasmid_52962

      DOI: 10.1016/j.ccell.2018.01.012

      Resource: RRID:Addgene_52962

      Curator: @Jmenke

      SciCrunch record: Plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818300126
  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Jan 2020
      plasmid_52962

      DOI: 10.1038/s41598-018-37940-6

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      Curator: @evieth

      SciCrunch record: plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6362041/