Hypothesis

526 Matching Annotations

Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Hippo pathway promotes platinum-based chemotherapy by inhibiting MTF1-dependent heavy metal response

1
1. scibot 16 Feb 2025
  
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  52,962
  
  DOI: 10.1186/s12885-025-13661-8
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11806854/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

1
1. scibot 16 Feb 2025
  
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  52962
  
  DOI: 10.1158/0008-5472.CAN-24-2330
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization

1
1. scibot 16 Feb 2025
  
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  52962
  
  DOI: 10.1038/s44319-024-00357-6
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
aacrjournals.org aacrjournals.org

MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)

1
1. scibot 13 Feb 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1158/1078-0432.CCR-24-1750
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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aacrjournals.org/clincancerres/article/30/22/5154/749570/MEK-Inhibitors-Lead-to-PDGFR-Pathway-Upregulation
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

7
1. scibot 07 Feb 2025
  
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  52962
  
  DOI: 10.1016/j.isci.2024.111444
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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  RRID:Addgene_52962
2. scibot 06 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 05 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 04 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 03 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 02 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 01 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
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URL

pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
www.sciencedirect.com www.sciencedirect.com

Tubular ER structures shaped by ER-phagy receptors engage in stress-induced Golgi bypass

1
1. scibot 07 Feb 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.devcel.2025.01.011
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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sciencedirect.com/science/article/pii/S1534580725000310
Jan 2025
aacrjournals.org aacrjournals.org

High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects

1
1. scibot 31 Jan 2025
  
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  RRID: Addgene_52962
  
  DOI: 10.1158/2326-6066.CIR-22-0815
  
  Resource: RRID:Addgene_52962
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:Addgene_52962
  
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aacrjournals.org/cancerimmunolres/article/11/7/895/727496/High-Expression-of-MHC-Class-I-Overcomes-Cancer
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

31
1. scibot 31 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 29 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 28 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 27 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 26 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 25 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
8. scibot 24 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
9. scibot 23 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
10. scibot 22 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
11. scibot 21 Jan 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
12. scibot 20 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
13. scibot 19 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
14. scibot 18 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
15. scibot 17 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
16. scibot 16 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
17. scibot 15 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
18. scibot 14 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
19. scibot 13 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
20. scibot 12 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
21. scibot 11 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
22. scibot 10 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
23. scibot 09 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
24. scibot 08 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
25. scibot 07 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
26. scibot 06 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
27. scibot 05 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
28. scibot 04 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
29. scibot 03 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
30. scibot 02 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
31. scibot 01 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
www.sciencedirect.com www.sciencedirect.com

Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

1
1. scibot 30 Jan 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.xcrm.2025.101928
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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sciencedirect.com/science/article/pii/S2666379125000011
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SLC35A2 gene product modulates paramyxovirus fusion events during infection

1
1. scibot 27 Jan 2025
  
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  52962
  
  DOI: 10.1371/journal.ppat.1012531
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11756793/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration

1
1. scibot 27 Jan 2025
  
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  52962
  
  DOI: 10.1038/s41598-024-83468-3
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma

1
1. scibot 27 Jan 2025
  
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  plasmid_52962
  
  DOI: 10.1038/s41698-024-00792-7
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11723958/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

1
1. scibot 17 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.xcrm.2024.101913
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
www.sciencedirect.com www.sciencedirect.com

The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells

1
1. scibot 07 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.chembiol.2024.11.009
  
  Resource: RRID:Addgene_52962
  
  Curator: @scibot
  
  SciCrunch record: RRID:Addgene_52962
  
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sciencedirect.com/science/article/pii/S2451945624004896
www.nature.com www.nature.com

Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents

1
1. scibot 04 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1038/s41598-024-80834-z
  
  Resource: RRID:Addgene_52962
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:Addgene_52962
  
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nature.com/articles/s41598-024-80834-z
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Identification of modulators of the ALT pathway through a native FISH-based optical screen

1
1. scibot 03 Jan 2025
  
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  Addgene52962
  
  DOI: 10.1016/j.celrep.2024.115114
  
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sciencedirect.com/science/article/pii/S2211124724014657
Dec 2024
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Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

4
1. scibot 31 Dec 2024
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Dec 2024
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 29 Dec 2024
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 28 Dec 2024
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1

1
1. scibot 29 Dec 2024
  
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  52962
  
  DOI: 10.1002/advs.202404620
  
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202404620
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EV‐Elute: A universal platform for the enrichment of functional surface marker‐defined extracellular vesicle subpopulations

1
1. scibot 28 Dec 2024
  
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  52962
  
  DOI: 10.1002/jev2.70017
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11653091/
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Targeting ketone body metabolism in mitigating gemcitabine resistance

1
1. scibot 27 Dec 2024
  
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  52962
  
  DOI: 10.1172/jci.insight.177840
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11665555/
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Gliocidin is a nicotinamide-mimetic prodrug that targets glioblastoma

1
1. scibot 27 Dec 2024
  
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  52962
  
  DOI: 10.1038/s41586-024-08224-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11665509/
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GO-CRISPR: A highly controlled workflow to discover gene essentiality in loss-of-function screens

1
1. scibot 27 Dec 2024
  
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  Addgene_52962
  
  DOI: 10.1371/journal.pone.0315923
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11654918/
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TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome

2
1. scibot 24 Dec 2024
  
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  AddgeneCat# 52962
  
  DOI: 10.1016/j.molcel.2024.11.007
  
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2. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.007
  
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sciencedirect.com/science/article/pii/S1097276524009122
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The carbonyl nucleobase adduct M3Ade is a potent antigen for adaptive polyclonal MR1-restricted T cells

1
1. scibot 24 Dec 2024
  
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  AddgeneCat#52962
  
  DOI: 10.1016/j.immuni.2024.11.019
  
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3D chromatin hubs as regulatory units of identity and survival in human acute leukemia

1
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.molcel.2024.11.040
  
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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells

1
1. scibot 14 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.isci.2024.111399
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11647120/
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Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer

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1. scibot 13 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1038/s44321-024-00161-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
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Control of cell proliferation by memories of mitosis

1
1. scibot 11 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1126/science.add9528
  
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Mitochondrial elongation impairs breast cancer metastasis

1
1. scibot 07 Dec 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1126/sciadv.adm8212
  
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science.org/doi/10.1126/sciadv.adm8212
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Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition

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  cat. no. 52962, Addgene
  
  DOI: 10.1038/s42255-024-01166-w
  
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nature.com/articles/s42255-024-01166-w
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Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors

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1. scibot 05 Dec 2024
  
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  Addgene_52962
  
  DOI: 10.1186/s13059-024-03438-w
  
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genomebiology.biomedcentral.com/articles/10.1186/s13059-024-03438-w
Nov 2024
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Endocrine persistence in ER+ breast cancer is accompanied by metabolic vulnerability in oxidative phosphorylation

1
1. scibot 20 Nov 2024
  
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  Addgene_52962
  
  DOI: 10.1101/2024.09.26.615177
  
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biorxiv.org/content/10.1101/2024.09.26.615177v1
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Mitochondrial elongation impairs breast cancer metastasis

1
1. scibot 10 Nov 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.1126/sciadv.adm8212
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11540020/
Sep 2024
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Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1126/sciadv.adl5638
  
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ncbi.nlm.nih.gov/pmc/articles/PMC466957/
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Genome-wide CRISPR screenings identified SMCHD1 as a host-restricting factor for AAV transduction

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1371/journal.ppat.1012344
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11257396/
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Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1038/s41467-024-50298-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11255242/
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The Aryl Hydrocarbon Receptor Controls IFNγ-Induced Immune Checkpoints PD-L1 and IDO via the JAK/STAT Pathway in Lung Adenocarcinoma

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1101/2024.08.12.607602
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11343147/
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CRISPR screen of venetoclax response-associated genes identifies transcription factor ZNF740 as a key functional regulator

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1038/s41419-024-06995-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11350041/
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Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization

1
1. scibot 29 Sep 2024
  
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  52962
  
  DOI: 10.1038/s41467-024-50498-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11358161/
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Mechanism for controlled assembly of transcriptional condensates by Aire

1
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  52962
  
  DOI: 10.1038/s41590-024-01922-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11362013/
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CRISPR-CLEAR: Nucleotide-Resolution Mapping of Regulatory Elements via Allelic Readout of Tiled Base Editing

1
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  52962
  
  DOI: 10.1101/2024.09.09.612085
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11419122/
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USP44 Overexpression Drives a MYC-Like Gene Expression Program in Neuroblastoma through Epigenetic Reprogramming

1
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  52962
  
  DOI: 10.1158/1541-7786.MCR-23-0454
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11372370/
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The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation

1
1. scibot 29 Sep 2024
  
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  plasmid_52962
  
  DOI: 10.1038/s41467-024-52049-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11374810/
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SLC35A2 modulates paramyxovirus fusion events during infection

1
1. scibot 28 Sep 2024
  
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  52962
  
  DOI: 10.1101/2024.08.27.609835
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11382999/
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BOD1L mediates chromatin binding and non-canonical function of H3K4 methyltransferase SETD1A

1
1. scibot 28 Sep 2024
  
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  Addgene_52962
  
  DOI: 10.1093/nar/gkae605
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11381347/
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Saturation mutagenesis-reinforced functional assays for disease-related genes

1
1. scibot 27 Sep 2024
  
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  Plasmid_52962
  
  DOI: 10.1016/j.cell.2024.08.047
  
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sciencedirect.com/science/article/pii/S0092867424009760
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HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

1
1. scibot 26 Sep 2024
  
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  52962
  
  DOI: 10.1016/j.molcel.2024.07.018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
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Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

1
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  52962
  
  DOI: 10.1101/2024.07.25.605204
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11291135/
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PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma

1
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  Plasmid_52962
  
  DOI: 10.1038/s41467-024-52507-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11413393/
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The Proteasome and Cul3-Dependent Protein Ubiquitination Is Required for Gli Protein-Mediated Activation of Gene Expression in the Hedgehog Pathway

1
1. scibot 25 Sep 2024
  
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  lentiCas9-Blast
  
  DOI: 10.3390/cells13171496
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11394618/
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GCN2 is a determinant of the response to WEE1 kinase inhibition in small-cell lung cancer

1
1. scibot 25 Sep 2024
  
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  52962
  
  DOI: 10.1016/j.celrep.2024.114606
  
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Targeting SNRNP200-induced splicing dysregulation offers an immunotherapy opportunity for glycolytic triple-negative breast cancer

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GeneRaMeN enables integration, comparison, and meta-analysis of multiple ranked gene lists to identify consensus, unique, and correlated genes

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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression

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Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma

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CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines

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IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling

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Protocol to identify receptors of secreted proteins through CRISPR-Cas9 whole-genome screening technology

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MIG6 loss increased RET inhibitor tolerant persister cells in RET-rearranged non-small cell lung cancer

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Shifts in receptors during submergence of an encephalitic arbovirus

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Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection

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Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma

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CRISPR-Cas9 screening develops an epigenetic and transcriptional gene signature for risk stratification and target prediction in neuroblastoma

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Specific multivalent molecules boost CRISPR-mediated transcriptional activation

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Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

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INAUGURAL ARTICLE by a Recently Elected Academy Member:Small-molecule inhibition of MAP2K4 is synergistic with RAS inhibitors in KRAS-mutant cancers

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CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism

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YTHDC1 m6A-dependent and m6A-independent functions converge to preserve the DNA damage response

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The SW480 cell line as a model of resident and migrating colon cancer stem cells

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SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation

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SMYD5 is a regulator of the mild hypothermia response

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Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs

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Library‐Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity

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A deep learning model of tumor cell architecture elucidates response and resistance to CDK4/6 inhibitors

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2024.04.26.591029v1.full-html.html

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Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription

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PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

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cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
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Modeling and therapeutic targeting of t(8;21) AML with/without TP53 deficiency

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A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

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The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1

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Netrin signaling mediates survival of dormant epithelial ovarian cancer cells

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The extracellular matrix integrates mitochondrial homeostasis

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DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer

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DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer

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Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer

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Synthetic lethal CRISPR screen identifies a cancer cell-intrinsic role of PD-L1 in regulation of vulnerability to ferroptosis

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Homologous recombination promotes mitotic death to suppress the innate immune response

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  DOI: 10.1101/2024.05.04.592546
  
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Original research: IFNγ mediates the resistance of tumor cells to distinct NK cell subsets

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  DOI: 10.1136/jitc-2024-009410
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11218003/
Jun 2024
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Human Coronavirus 229E Infection Inactivates Pyroptosis Executioner Gasdermin D but Ultimately Leads to Lytic Cell Death Partly Mediated by Gasdermin E

1
1. scibot 30 Jun 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11209299/
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An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity

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A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans

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ncbi.nlm.nih.gov/pmc/articles/PMC11142209/
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Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential

1
1. scibot 21 Jun 2024
  
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  DOI: 10.21203/rs.3.rs-4462139/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11160910/
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Genome-wide screening identifies Trim33 as an essential regulator of dendritic cell differentiation

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The integrin CD11b inhibits MSU-induced NLRP3 inflammasome activation in macrophages and protects mice against MSU-induced joint inflammation

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ncbi.nlm.nih.gov/pmc/articles/PMC11165854/
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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

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ncbi.nlm.nih.gov/pmc/articles/PMC11148184/
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A synthetic lethal dependency on casein kinase 2 in response to replication-perturbing therapeutics in RB1-deficient cancer cells

2
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  DOI: 10.1126/sciadv.adj1564
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11114247/
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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

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Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta

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  DOI: 10.1016/j.isci.2024.109921
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11133927/
May 2024
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The Hippo kinases control inflammatory Hippo signaling and restrict bacterial infection in phagocytes

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ncbi.nlm.nih.gov/pmc/articles/PMC11078001/
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Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

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sciencedirect.com/science/article/pii/S2211124724005394
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De novo generation of multi-target compounds using deep generative chemistry

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  DOI: 10.1038/s41467-024-47120-y
  
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nature.com/articles/s41467-024-47120-y
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Methyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition

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  plasmid_52962
  
  DOI: 10.1038/s12276-024-01205-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11058268/
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Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

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1. scibot 03 May 2024
  
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  RRID:Addgene_52962
  
  DOI: 10.7554/eLife.90683
  
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elifesciences.org/articles/90683
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Pooled multicolour tagging for visualizing subcellular protein dynamics

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  RRID:Addgene_52962
  
  DOI: 10.1038/s41556-024-01407-w
  
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nature.com/articles/s41556-024-01407-w
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Clinical Correlates of Venetoclax-Based Combination Sensitivities to Augment Acute Myeloid Leukemia Therapy

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ncbi.nlm.nih.gov/pmc/articles/PMC10618724/
Apr 2024
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GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies

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MYADM binds human parechovirus 1 and is essential for viral entry

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  DOI: 10.1038/s41467-024-47825-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043367/
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Increased frequency of CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression without inducing homologous recombination deficiency

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ncbi.nlm.nih.gov/pmc/articles/PMC11030533/
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IGSF8 is an innate immune checkpoint and cancer immunotherapy target

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Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma

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  plasmid_52962
  
  DOI: 10.1038/s41467-024-47771-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11039739/
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ERG activates a stem-like proliferation-differentiation program in prostate epithelial cells with mixed basal-luminal identity

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  DOI: 10.1101/2023.05.15.540839
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10996491/
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Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity

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ncbi.nlm.nih.gov/pmc/articles/PMC11009675/
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Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia

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  https://www.addgene.org/52962/
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11014662/
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TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers

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  DOI: 10.1038/s41419-024-06654-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11024179/
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Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis

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  DOI: 10.1038/s41467-024-46602-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
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A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens

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  DOI: 10.1038/s41594-024-01211-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10948361/
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HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14

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  Addgene_52962
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10942435/
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A fast-acting lipid checkpoint in G1 prevents mitotic defects

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  plasmid_52962
  
  DOI: 10.1038/s41467-024-46696-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10948896/
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Activation of the insulin receptor by insulin-like growth factor 2

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ncbi.nlm.nih.gov/pmc/articles/PMC10960814/
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Mitochondrial injury induced by a Salmonella genotoxin triggers the proinflammatory senescence-associated secretory phenotype

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  DOI: 10.1038/s41467-024-47190-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10981749/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma

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  RRID:Addgene_52962
  
  DOI: 10.1002/jcb.30542
  
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onlinelibrary.wiley.com/doi/10.1002/jcb.30542
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Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

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  RRID:Addgene_52962
  
  DOI: 10.1016/j.celrep.2024.114041
  
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sciencedirect.com/science/article/pii/S2211124724003693
Mar 2024
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CRISPR/Cas9 targeting of passenger single nucleotide variants in haploinsufficient or essential genes expands cancer therapy prospects

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ncbi.nlm.nih.gov/pmc/articles/PMC10978915/
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Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry

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  DOI: 10.1016/j.crmeth.2024.100737
  
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A gut-derived hormone regulates cholesterol metabolism

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  RRID:Addgene_52962
  
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Genetic determinants of micronucleus formation in vivo

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1. scibot 17 Mar 2024
  
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Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells

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1. scibot 17 Mar 2024
  
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  52962
  
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A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells

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Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer

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Functionally-instructed modifiers of response to ATR inhibition in experimental glioma

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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

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In vivo CRISPR screening directly targeting testicular cells

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Extracting, filtering and simulating cellular barcodes using CellBarcode tools

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Feb 2024
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A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis

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  AddgeneCat#52962
  
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Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery

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1. scibot 29 Feb 2024
  
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  DOI: 10.1126/sciadv.adk3127
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10889360/
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Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons

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  plasmid_52962
  
  DOI: 10.1126/sciadv.adj4767
  
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Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1

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Saturation resistance profiling of EGFR variants against tyrosine kinase inhibitors using prime editing

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Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

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  Plasmid_52962
  
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Alternative polyadenylation determines the functional landscape of inverted Alu repeats

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  AddgeneCat# 52962
  
  DOI: 10.1016/j.molcel.2024.01.008
  
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RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9

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  52,962
  
  DOI: 10.1186/s13059-023-03149-8
  
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Mitochondrial-encoded complex I impairment induces a targetable dependency on aerobic fermentation in Hürthle cell carcinoma of the thyroid

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Multiplexed screening reveals how cancer-specific alternative polyadenylation shapes tumor growth in vivo

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  DOI: 10.1038/s41467-024-44931-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10834521/
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METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation

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  52962
  
  DOI: 10.1186/s13045-024-01526-9
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10835888/
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Two-step evolution of HIV-1 budding system leading to pandemic in the human population

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sciencedirect.com/science/article/pii/S2211124724000251
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Cell surface RNAs control neutrophil recruitment

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Cooperative function of oncogenic MAPK signaling and the loss of Pten for melanoma migration through the formation of lamellipodia

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  DOI: 10.1038/s41598-024-52020-8
  
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Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors

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EGFR-activated myofibroblasts promote metastasis of pancreatic cancer

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Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

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1. scibot 20 Dec 2023
  
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  RRID:Addgene_52962
  
  DOI: 10.1158/0008-5472.CAN-22-2948
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
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Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers

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  RRID:Addgene_52962
  
  DOI: 10.1016/j.immuni.2023.11.008
  
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Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

1
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  RRID:Addgene_52962
  
  DOI: 10.7554/eLife.87098
  
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Nov 2023
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Targeting the TCA cycle through cuproptosis confers synthetic lethality on ARID1A-deficient hepatocellular carcinoma

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  DOI: 10.1016/j.xcrm.2023.101264
  
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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation

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The promiscuous development of an unconventional Qa1b-restricted T cell population

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  RRID:Addgene_52962
  
  DOI: 10.3389/fimmu.2023.1250316
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10644506/
Oct 2023
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Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level

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  RRID:Addgene_52962
  
  DOI: 10.1101/2023.10.16.562592
  
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biorxiv.org/content/10.1101/2023.10.16.562592v1
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Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus

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  RRID:Addgene_52962
  
  DOI: 10.1101/2023.10.20.563362
  
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