863 Matching Annotations
  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
    1
    1. scibot 16 Jan 2022
      AddgeneCat#52961

      DOI: 10.1016/j.celrep.2021.110236

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    sciencedirect.com/science/article/pii/S2211124721017459
  3. www.sciencedirect.com www.sciencedirect.com
    Modeling cell protrusion predicts how Myosin II and actin turnover affect adhesion-based signaling
    1
    1. scibot 12 Jan 2022
      RRID:Addgene_52961

      DOI: 10.1016/j.bpj.2021.11.2889

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    sciencedirect.com/science/article/pii/S0006349521038820
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.12.10.472112
    1
    1. scibot 05 Jan 2022
      RRID:Addgene_52961

      DOI: 10.1101/2021.12.10.472112

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    ncbi.nlm.nih.gov/pmc/articles/PMC8687463/
  5. Dec 2021
  6. www.sciencedirect.com www.sciencedirect.com
    Assessing kinetics and recruitment of DNA repair factors using high content screens
    1
    1. scibot 29 Dec 2021
      Plasmid_52961

      DOI: 10.1016/j.celrep.2021.110176

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    sciencedirect.com/science/article/pii/S2211124721016764
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
    1
    1. scibot 11 Dec 2021
      Plasmid_52961

      DOI: 10.1016/j.isci.2021.103448

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    ncbi.nlm.nih.gov/pmc/articles/PMC8633987/
  8. www.sciencedirect.com www.sciencedirect.com
    Genome-wide fitness gene identification reveals Roquin as a potent suppressor of CD8 T cell expansion and anti-tumor immunity
    1
    1. scibot 08 Dec 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2021.110083

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    sciencedirect.com/science/article/pii/S2211124721015746
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Beta-Tubulin Isotype TUBB6 Controls Microtubule and Actin Dynamics in Osteoclasts
    1
    1. scibot 04 Dec 2021
      RRID:Addgene_52961

      DOI: 10.3389/fcell.2021.778887

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639228/
  10. Nov 2021
  11. www.sciencedirect.com www.sciencedirect.com
    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
    1
    1. scibot 30 Nov 2021
      Cat# 52961

      DOI: 10.1016/j.molcel.2021.10.028

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    sciencedirect.com/science/article/pii/S1097276521009485
  12. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia
    1
    1. scibot 30 Nov 2021
      addgene_52961

      DOI: 10.1111/jcmm.17060

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    onlinelibrary.wiley.com/doi/10.1111/jcmm.17060
  13. www.sciencedirect.com www.sciencedirect.com
    PALP: A rapid imaging technique for stratifying ferroptosis sensitivity in normal and tumor tissues in situ
    1
    1. scibot 23 Nov 2021
      Addgene, Cat# 52961

      DOI: 10.1016/j.chembiol.2021.11.001

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    sciencedirect.com/science/article/pii/S2451945621004785
  14. www.nature.com www.nature.com
    Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer
    1
    1. scibot 21 Nov 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41467-021-26823-6

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    nature.com/articles/s41467-021-26823-6
  15. www.sciencedirect.com www.sciencedirect.com
    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
    1
    1. scibot 10 Nov 2021
      plasmid_52961

      DOI: 10.1016/j.celrep.2021.109979

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    sciencedirect.com/science/article/pii/S2211124721014583
  16. Oct 2021
  17. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
    1
    1. scibot 29 Oct 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.isci.2021.103224

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    sciencedirect.com/science/article/pii/S2589004221011925
  18. www.sciencedirect.com www.sciencedirect.com
    GCN2 adapts protein synthesis to scavenging-dependent growth
    1
    1. scibot 27 Oct 2021
      Plasmid_52961

      DOI: 10.1016/j.cels.2021.09.014

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    sciencedirect.com/science/article/pii/S2405471221003823
  19. www.sciencedirect.com www.sciencedirect.com
    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
    1
    1. scibot 23 Oct 2021
      52961

      DOI: 10.1016/j.molcel.2021.10.005

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    sciencedirect.com/science/article/pii/S1097276521008340
  20. www.sciencedirect.com www.sciencedirect.com
    NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression
    1
    1. scibot 21 Oct 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109856

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    sciencedirect.com/science/article/pii/S2211124721013231
  21. www.sciencedirect.com www.sciencedirect.com
    Aberrant RNA methylation triggers recruitment of an alkylation repair complex
    1
    1. scibot 21 Oct 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2021.09.024

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    sciencedirect.com/science/article/pii/S1097276521007772
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites
    1
    1. scibot 18 Oct 2021
      RRID:Addgene_52961

      DOI: 10.1111/febs.16202

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16202
  23. academic.oup.com academic.oup.com
    A role for AKT1 in nonsense-mediated mRNA decay
    1
    1. scibot 15 Oct 2021
      RRID:Addgene_52961

      DOI: 10.1093/nar/gkab882

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab882/6389627
  24. www.sciencedirect.com www.sciencedirect.com
    Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation
    1
    1. scibot 09 Oct 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2021.09.015

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    sciencedirect.com/science/article/pii/S1534580721007334
  25. Sep 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Corrigendum: Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
    1
    1. scibot 30 Sep 2021
      plasmid_52961

      DOI: 10.3389/fimmu.2021.763899

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    ncbi.nlm.nih.gov/pmc/articles/PMC8474018/
  27. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
      Addgene_52961

      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  28. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis
    1
    1. scibot 24 Sep 2021
      52961

      DOI: 10.1016/j.molcel.2021.08.039

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    sciencedirect.com/science/article/pii/S1097276521007292
  29. www.sciencedirect.com www.sciencedirect.com
    MultiEditR: The first tool for detection and quantification of multiple RNA editing sites from Sanger sequencing demonstrates comparable fidelity to RNA-seq
    1
    1. scibot 24 Sep 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.omtn.2021.07.008

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    sciencedirect.com/science/article/pii/S2162253121001761
  30. www.sciencedirect.com www.sciencedirect.com
    NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis
    1
    1. scibot 23 Sep 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2021.08.034

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    sciencedirect.com/science/article/pii/S1097276521007140
  31. www.nature.com www.nature.com
    Exosomal miR-19a and IBSP cooperate to induce osteolytic bone metastasis of estrogen receptor-positive breast cancer
    1
    1. scibot 16 Sep 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41467-021-25473-y

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    nature.com/articles/s41467-021-25473-y
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZFP36L2 Role in Thyroid Functionality
    1
    1. scibot 14 Sep 2021
      RRID:Addgene_52961

      DOI: 10.3390/ijms22179379

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    ncbi.nlm.nih.gov/pmc/articles/PMC8431063/
  33. www.sciencedirect.com www.sciencedirect.com
    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
    1
    1. scibot 11 Sep 2021
      Cat# 52961

      DOI: 10.1016/j.cmet.2021.08.012

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    sciencedirect.com/science/article/pii/S1550413121003752
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog—GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition
    1
    1. scibot 04 Sep 2021
      RRID:Addgene_52961

      DOI: 10.3390/cancers13164227

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    ncbi.nlm.nih.gov/pmc/articles/PMC8394935/
  35. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Chemoresistance is mediated by ovarian cancer leader cells in vitro
    1
    1. scibot 03 Sep 2021
      Addgene_52961

      DOI: 10.1186/s13046-021-02086-3

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    jeccr.biomedcentral.com/articles/10.1186/s13046-021-02086-3
  36. Aug 2021
  37. link.springer.com link.springer.com
    Derivation and characterization of an HIV-1 mutant that rescues IP6 binding deficiency
    1
    1. scibot 31 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1186/s12977-021-00571-3

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    link.springer.com/article/10.1186/s12977-021-00571-3
  38. www.sciencedirect.com www.sciencedirect.com
    KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2
    1
    1. scibot 31 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1182/bloodadvances.2020002819

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    sciencedirect.com/science/article/pii/S2473952921004171
  39. www.sciencedirect.com www.sciencedirect.com
    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
    1
    1. scibot 25 Aug 2021
      Addgene 52961

      DOI: 10.1016/j.celrep.2021.109596

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    sciencedirect.com/science/article/pii/S2211124721010342
  40. www.sciencedirect.com www.sciencedirect.com
    Establishment of a GFP::LMNB1 knockin cell line (CSUi002-A-1) from a dystonia patient-specific iPSC by CRISPR/Cas9 editing
    1
    1. scibot 19 Aug 2021
      addgene_52961

      DOI: 10.1016/j.scr.2021.102505

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    sciencedirect.com/science/article/pii/S1873506121003524
  41. academic.oup.com academic.oup.com
    Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1
    1
    1. scibot 17 Aug 2021
      plasmid_52961

      DOI: 10.1093/narcan/zcab033

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    academic.oup.com/narcancer/article/3/3/zcab033/6352433
  42. 52.53.155.43 52.53.155.43
    Treatment of RB1-intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy
    1
    1. scibot 16 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1002/hep.31872

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    52.53.155.43/d535e061bd39448f0bff90d2d8bad0476300ef0d/hep.31872 (1)-html.html
  43. 52.53.155.43 52.53.155.43
    hep.31872-html.html
    1
    1. scibot 16 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1002/HEP.31872

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    52.53.155.43/9141f02023b9cd2a20a0ded8540f4e4d455d9808/hep.31872-html.html
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    1
    1. scibot 15 Aug 2021
      RRID:Addgene_52961

      DOI: 10.7554/eLife.66524

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    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
    1
    1. scibot 15 Aug 2021
      Addgene_52961

      DOI: 10.1158/2159-8290.CD-20-0331

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    ncbi.nlm.nih.gov/pmc/articles/PMC8110214/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
    1
    1. scibot 15 Aug 2021
      plasmid_52961

      DOI: 10.1158/2159-8290.CD-20-0775

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858242/
  47. www.sciencedirect.com www.sciencedirect.com
    RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
    1
    1. scibot 14 Aug 2021
      addgene_52961

      DOI: 10.1016/j.celrep.2021.109451

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    sciencedirect.com/science/article/pii/S2211124721008688
  48. www.sciencedirect.com www.sciencedirect.com
    Identification of novel TGF-β regulated genes with pro-migratory roles
    1
    1. scibot 14 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.bbadis.2019.165537

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    sciencedirect.com/science/article/pii/S0925443919302601
  49. www.biorxiv.org www.biorxiv.org
    Untitled document
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    1. scibot 13 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1101/633685

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    Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
    1
    1. scibot 13 Aug 2021
      Addgene_52961

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    sciencedirect.com/science/article/pii/S2405471219301176
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions
    1
    1. scibot 13 Aug 2021
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6421364/
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    Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor
    1
    1. scibot 11 Aug 2021
      Plasmid_52961

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    sciencedirect.com/science/article/pii/S0092867416313083
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 09 Aug 2021
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6251623/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects
    1
    1. scibot 06 Aug 2021
      Addgene catalog no. 52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282625/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
  58. elifesciences.org elifesciences.org
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    elifesciences.org/articles/31023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
    1
    1. scibot 06 Aug 2021
      RRID:Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321670/
  60. www.sciencedirect.com www.sciencedirect.com
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      plasmid_52961

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    sciencedirect.com/science/article/pii/S1535610818305270
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
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    sciencedirect.com/science/article/pii/S0092867418315630
  63. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
    1
    1. scibot 04 Aug 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S1931312818305584
  64. www.sciencedirect.com www.sciencedirect.com
    Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity
    1
    1. scibot 03 Aug 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S235239642100298X
  65. www.nature.com www.nature.com
    Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma
    1
    1. scibot 02 Aug 2021
      Plasmid_52961

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    nature.com/articles/s41467-018-05029-3
  66. Jul 2021
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 31 Jul 2021
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6336405/
  68. www.sciencedirect.com www.sciencedirect.com
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      Plasmid_52961

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    sciencedirect.com/science/article/pii/S1550413118307575
  69. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
    1
    1. scibot 30 Jul 2021
      pLentiCRISPR v2

      DOI: 10.1016/j.molcel.2019.07.021

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    sciencedirect.com/science/article/pii/S1097276519305519
  70. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening
    1
    1. scibot 30 Jul 2021
      Addgene_52961

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    sciencedirect.com/science/article/pii/S1097276516308644
  71. www.sciencedirect.com www.sciencedirect.com
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      Plasmid_52961

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    sciencedirect.com/science/article/pii/S2211124718315316
  72. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 29 Jul 2021
      RRID: Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124719311088
  73. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
    1
    1. scibot 29 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2019.06.014

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    sciencedirect.com/science/article/pii/S0092867419306774
  74. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
    1. scibot 29 Jul 2021
      RRID: Addgene_52961

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    sciencedirect.com/science/article/pii/S1097276519304022
  75. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 29 Jul 2021
      lenti-CRISPRv2

      DOI: 10.1016/j.celrep.2019.07.027

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    sciencedirect.com/science/article/pii/S2211124719309246
  76. www.sciencedirect.com www.sciencedirect.com
    Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
    1
    1. scibot 29 Jul 2021
      lentiCRISPRv2

      DOI: 10.1016/j.str.2019.05.011

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    sciencedirect.com/science/article/pii/S096921261930173X
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC5562512/
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
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  80. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
    1
    1. scibot 28 Jul 2021
      Addgene#52961

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    sciencedirect.com/science/article/pii/S1074761319300305
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      Plasmid_52961

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  82. www.sciencedirect.com www.sciencedirect.com
    Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
    1
    1. scibot 27 Jul 2021
      52961

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  83. www.sciencedirect.com www.sciencedirect.com
    Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS
    1
    1. scibot 27 Jul 2021
      52961

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  84. rupress.org rupress.org
    A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers
    1
    1. scibot 23 Jul 2021
      Addgene_52961

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  85. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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      RRID:Addgene_52961

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  86. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
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    1. scibot 22 Jul 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124721007920
  87. www.nature.com www.nature.com
    The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases
    1
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      RRID:Addgene_52961

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of immune cell reactivity with cis-binding Siglec agonists
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    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1073/pnas.2012408118

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    ncbi.nlm.nih.gov/pmc/articles/PMC7826350/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
    1
    1. scibot 14 Jul 2021
      Plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC8274936/
  90. www.sciencedirect.com www.sciencedirect.com
    BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
    1
    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109359

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    sciencedirect.com/science/article/pii/S2211124721007579
  91. www.sciencedirect.com www.sciencedirect.com
    MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development
    1
    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109390

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    sciencedirect.com/science/article/pii/S2211124721007889
  92. www.sciencedirect.com www.sciencedirect.com
    Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models
    1
    1. scibot 13 Jul 2021
      RRID:Addgene_529

      DOI: 10.1016/j.xpro.2021.100668

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  93. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
    1
    1. scibot 03 Jul 2021
      Cat# 52961

      DOI: 10.1016/j.molcel.2021.06.014

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
  94. Jun 2021
  95. bloodcancerdiscov.aacrjournals.org bloodcancerdiscov.aacrjournals.org
    SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
    1
    1. scibot 29 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1158/2643-3230.BCD-20-0168

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    bloodcancerdiscov.aacrjournals.org/content/2/3/266
  96. www.sciencedirect.com www.sciencedirect.com
    The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
    1
    1. scibot 25 Jun 2021
      Cat#52961

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    sciencedirect.com/science/article/pii/S1535610821002865
  97. www.cmghjournal.org www.cmghjournal.org
    Sestrin proteins protect against lipotoxicity-induced oxidative stress in the liver via suppression of c-Jun N-terminal kinases: Short title: Sestrins ameliorate hepatic lipotoxicity
    1
    1. scibot 25 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.jcmgh.2021.04.015

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    cmghjournal.org/article/S2352-345X(21)00086-2/abstract
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA
    1
    1. scibot 17 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1158/2643-3230.bcd-20-0168

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    ncbi.nlm.nih.gov/pmc/articles/PMC8133360/
  99. www.cell.com www.cell.com
    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
    1
    1. scibot 15 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2021.05.007

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    cell.com/cancer-cell/fulltext/S1535-6108(21)00273-7
  100. May 2021
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
    1
    1. scibot 27 May 2021
      Addgene_52961

      DOI: 10.7554/eLife.64930

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    ncbi.nlm.nih.gov/pmc/articles/PMC8139829/
  102. www.cell.com www.cell.com
    TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis
    1
    1. scibot 20 May 2021
      Cat# 52961

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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00223-0
  103. www.sciencedirect.com www.sciencedirect.com
    Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage
    1
    1. scibot 15 May 2021
      Cat# 52961

      DOI: 10.1016/j.immuni.2020.06.007

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    sciencedirect.com/science/article/pii/S1074761320302375
  104. www.nature.com www.nature.com
    YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
    1
    1. scibot 15 May 2021
      Addgene_52961

      DOI: 10.1038/s41467-021-22987-3

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    nature.com/articles/s41467-021-22987-3
  105. www.sciencedirect.com www.sciencedirect.com
    Rab34 is necessary for early stages of intracellular ciliogenesis
    1
    1. scibot 14 May 2021
      plasmid_52961

      DOI: 10.1016/j.cub.2021.04.018

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    sciencedirect.com/science/article/pii/S0960982221005315
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Giantin is required for intracellular N-terminal processing of type I procollagen
    1
    1. scibot 12 May 2021
      plasmid_52961

      DOI: 10.1083/jcb.202005166

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    ncbi.nlm.nih.gov/pmc/articles/PMC8103548/
  107. jvi.asm.org jvi.asm.org
    Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation
    1
    1. scibot 11 May 2021
      RRID:Addgene_52961

      DOI: 10.1128/JVI.00453-21

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    jvi.asm.org/content/95/11/e00453-21
  108. www.eneuro.org www.eneuro.org
    FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development
    1
    1. scibot 10 May 2021
      RRID:Addgene_52961

      DOI: 10.1523/ENEURO.0193-20.2021

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    eneuro.org/content/8/2/ENEURO.0193-20.2021
  109. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Follicular lymphoma-associated BTK mutations are inactivating resulting in augmented AKT activation
    1
    1. scibot 10 May 2021
      Addgene_52961

      DOI: 10.1158/1078-0432.CCR-20-3741

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    clincancerres.aacrjournals.org/content/27/8/2301
  110. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
    1
    1. scibot 09 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.09.019

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    sciencedirect.com/science/article/pii/S193459092030494X
  111. www.sciencedirect.com www.sciencedirect.com
    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
    1
    1. scibot 09 May 2021
      Addgene_52961

      DOI: 10.1016/j.stem.2020.12.008

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    sciencedirect.com/science/article/pii/S1934590920305920
  112. www.sciencedirect.com www.sciencedirect.com
    Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
    1
    1. scibot 09 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.12.009

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    sciencedirect.com/science/article/pii/S1934590920305932
  113. www.sciencedirect.com www.sciencedirect.com
    Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
    1
    1. scibot 08 May 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2021.01.019

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    sciencedirect.com/science/article/pii/S1097276521000393
  114. www.sciencedirect.com www.sciencedirect.com
    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    1
    1. scibot 08 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2020.10.021

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    sciencedirect.com/science/article/pii/S1097276520307280
  115. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    1. scibot 07 May 2021
      plasmid_52961

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  116. jasn.asnjournals.org jasn.asnjournals.org
    SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance
    1
    1. scibot 07 May 2021
      RRID:Addgene_52961

      DOI: 10.1681/ASN.2020081126

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    jasn.asnjournals.org/content/32/3/563
  117. www.sciencedirect.com www.sciencedirect.com
    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
    1
    1. scibot 07 May 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2020.05.011

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    sciencedirect.com/science/article/pii/S1097276520303129
  118. www.sciencedirect.com www.sciencedirect.com
    3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
    1
    1. scibot 06 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2021.02.017

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    sciencedirect.com/science/article/pii/S153458072100157X
  119. www.sciencedirect.com www.sciencedirect.com
    Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
    2
    1. scibot 05 May 2021
      Cat#52961

      DOI: 10.1016/j.devcel.2020.09.011

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      Addgene_52961

      DOI: 10.1016/j.devcel.2020.09.011

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    sciencedirect.com/science/article/pii/S1534580720307139
  120. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis
    1
    1. scibot 05 May 2021
      Plasmid_52961

      DOI: 10.1016/j.devcel.2020.08.009

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    sciencedirect.com/science/article/pii/S1534580720306675
  121. www.sciencedirect.com www.sciencedirect.com
    Glutamine Metabolism Controls Chondrocyte Identity and Function
    1
    1. scibot 04 May 2021
      Addgene plasmid repository #52961

      DOI: 10.1016/j.devcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1534580720303579
  122. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism
    1
    1. scibot 04 May 2021
      plasmid_52961

      DOI: 10.1016/j.jlr.2021.100082

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    sciencedirect.com/science/article/pii/S002222752100064X
  123. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
    1
    1. scibot 01 May 2021
      Cat#52961

      DOI: 10.1016/j.cmet.2021.03.003

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    sciencedirect.com/science/article/pii/S1550413121001108
  124. Apr 2021
  125. www.sciencedirect.com www.sciencedirect.com
    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
    1
    1. scibot 30 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.cmet.2020.10.020

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    sciencedirect.com/science/article/pii/S1550413120305532
  126. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
    1
    1. scibot 29 Apr 2021
      plasmid_52961

      DOI: 10.1016/j.cmet.2020.10.018

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    sciencedirect.com/science/article/pii/S1550413120305519
  127. www.sciencedirect.com www.sciencedirect.com
    Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
    1
    1. scibot 28 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.chom.2020.05.012

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    sciencedirect.com/science/article/pii/S1931312820302948
  128. www.sciencedirect.com www.sciencedirect.com
    Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability
    1
    1. scibot 28 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.chom.2020.05.011

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    sciencedirect.com/science/article/pii/S1931312820302936
  129. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Plasmid_52961

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  130. www.sciencedirect.com www.sciencedirect.com
    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
    1
    1. scibot 24 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.10.046

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    sciencedirect.com/science/article/pii/S0092867420314537
  131. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
    1
    1. scibot 23 Apr 2021
      Addgene Cat# 52961

      DOI: 10.1016/j.cell.2020.05.040

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    sciencedirect.com/science/article/pii/S0092867420306735
  132. www.sciencedirect.com www.sciencedirect.com
    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
      Plasmid Cat#52961

      DOI: 10.1016/j.ccell.2020.11.004

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    sciencedirect.com/science/article/pii/S1535610820305961
  133. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
    1
    1. scibot 21 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109010

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    sciencedirect.com/science/article/pii/S2211124721003247
  134. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
    1. scibot 17 Apr 2021
      Cat# 52961

      DOI: 10.1016/j.ccell.2020.04.016

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    sciencedirect.com/science/article/pii/S1535610820302154
  135. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    1. scibot 17 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2020.06.002

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    sciencedirect.com/science/article/pii/S1535610820302750
  136. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
    1. scibot 17 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.ccell.2020.04.014

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    sciencedirect.com/science/article/pii/S1535610820302130
  137. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2021.03.034

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    sciencedirect.com/science/article/pii/S109727652100229X
  138. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
      Plasmid_52961

      DOI: 10.1016/j.molcel.2021.02.033

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  139. www.sciencedirect.com www.sciencedirect.com
    Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation
    1
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    sciencedirect.com/science/article/pii/S2451945621000519
  140. www.sciencedirect.com www.sciencedirect.com
    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
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  141. journals.plos.org journals.plos.org
    Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection
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      DOI: 10.1371/journal.ppat.1009491

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  142. Mar 2021
  143. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
    1
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    sciencedirect.com/science/article/pii/S2211124721001972
  144. www.sciencedirect.com www.sciencedirect.com
    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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    sciencedirect.com/science/article/pii/S2211124721001546
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
    1
    1. scibot 10 Mar 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC7933353/
  146. www.sciencedirect.com www.sciencedirect.com
    The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
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    sciencedirect.com/science/article/pii/S1074761320304684
  147. www.sciencedirect.com www.sciencedirect.com
    Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling
    1
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    sciencedirect.com/science/article/pii/S2211124721000735
  148. www.frontiersin.org www.frontiersin.org
    Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
    1
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      DOI: 10.3389/fimmu.2021.619362

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    frontiersin.org/article/10.3389/fimmu.2021.619362/full
  149. Feb 2021
  150. www.sciencedirect.com www.sciencedirect.com
    Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites
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    1. scibot 28 Feb 2021
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    sciencedirect.com/science/article/pii/S1534580720310200
  151. www.pnas.org www.pnas.org
    The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6
    1
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      DOI: 10.1073/pnas.2015887118

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    pnas.org/content/118/1/e2015887118
  152. www.nature.com www.nature.com
    Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
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    nature.com/articles/s41467-020-17089-5
  153. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy
    1
    1. scibot 25 Feb 2021
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    mct.aacrjournals.org/content/19/5/1157
  154. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteasome inhibitors and Smac mimetics cooperate to induce cell death in Diffuse Large B‐cell Lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32976
  155. journals.sagepub.com journals.sagepub.com
    A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway - Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch,
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    journals.sagepub.com/doi/full/10.1177/1753425920915507
  156. www.nature.com www.nature.com
    Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages
    1
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      DOI: 10.1038/s41598-021-82137-z

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    nature.com/articles/s41598-021-82137-z
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RB1 Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1128/MCB.00105-19

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    ncbi.nlm.nih.gov/pmc/articles/PMC6664603/
  158. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
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    1. scibot 24 Feb 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S1535610819305720
  159. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  160. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
    1
    1. scibot 24 Feb 2021
      Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124721000620
  161. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
    1
    1. scibot 13 Feb 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S2211124720301649
  162. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
    1
    1. scibot 11 Feb 2021
      Plasmid_52961

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    sciencedirect.com/science/article/pii/S153561082030101X
  163. www.sciencedirect.com www.sciencedirect.com
    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
    1
    1. scibot 11 Feb 2021
      Addgene_52961

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    sciencedirect.com/science/article/pii/S221112472030231X
  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy
    1
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      RRID:Addgene_52961

      DOI: 10.3389/fmicb.2020.613963

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    ncbi.nlm.nih.gov/pmc/articles/PMC7862720/
  165. Jan 2021
  166. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2666166721000149
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
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  168. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    1
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S1934590920301387
  169. www.sciencedirect.com www.sciencedirect.com
    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis
    1
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124720306203
  170. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 15 Jan 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S0092867420306863
  171. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
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      Addgene_52961

      DOI: 10.1016/j.chom.2020.04.024

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    sciencedirect.com/science/article/pii/S1931312820302511
  172. www.sciencedirect.com www.sciencedirect.com
    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
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    sciencedirect.com/science/article/pii/S2211124720315758
  173. Dec 2020
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes
    1
    1. scibot 25 Dec 2020
      RRID:Addgene_52961

      DOI: 10.1128/IAI.00017-20

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  175. www.sciencedirect.com www.sciencedirect.com
    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
    1
    1. scibot 24 Dec 2020
      lentiCRISPR v2

      DOI: 10.1016/j.cub.2020.11.052

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    sciencedirect.com/science/article/pii/S0960982220317656
  176. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S1097276520308984
  177. www.cell.com www.cell.com
    Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors
    1
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    cell.com/developmental-cell/fulltext/S1534-5807(20)30794-2
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7566881/
  179. www.nature.com www.nature.com
    Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria
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      RRID:Addgene_52961

      DOI: 10.1038/s41419-020-03220-3

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    nature.com/articles/s41419-020-03220-3
  180. Nov 2020
  181. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
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      plasmid_52961

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    nature.com/articles/s41419-020-03159-5
  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest
    1
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      RRID:Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7648617/
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
    1
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      RRID:Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7737474/
  184. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
    1
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      Addgene_52961

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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
    1
    1. scibot 12 Nov 2020
      plasmid_52961

      DOI: 10.3389/fimmu.2020.571334

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    ncbi.nlm.nih.gov/pmc/articles/PMC7593769/
  186. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
    1
    1. scibot 05 Nov 2020
      LentiCRISPRv2

      DOI: 10.1016/j.cell.2020.10.028

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    sciencedirect.com/science/article/pii/S0092867420313921
  187. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
    1
    1. scibot 03 Nov 2020
      Addgene_52961

      DOI: 10.1016/j.molcel.2020.10.005

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    pubmed.ncbi.nlm.nih.gov/33108759/
  188. Oct 2020
  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
    1
    1. scibot 24 Oct 2020
      plasmid_52961

      DOI: 10.1186/s12885-020-07513-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC7568422/
  190. www.nature.com www.nature.com
    ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis
    1
    1. scibot 21 Oct 2020
      plasmid_52961

      DOI: 10.1038/s41417-020-00245-w

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    nature.com/articles/s41417-020-00245-w
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation
    1
    1. scibot 14 Oct 2020
      plasmid_52961

      DOI: 10.1016/j.celrep.2020.108086

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    ncbi.nlm.nih.gov/pmc/articles/PMC7545232/
  192. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
    1. scibot 13 Oct 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  193. www.frontiersin.org www.frontiersin.org
    Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
    1
    1. scibot 09 Oct 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.565924

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    frontiersin.org/article/10.3389/fimmu.2020.565924/full
  194. Sep 2020
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linker histone H1.2 and H1.4 affect the neutrophil lineage determination
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.52563

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    ncbi.nlm.nih.gov/pmc/articles/PMC7250579/
  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1002/1878-0261.12753

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    ncbi.nlm.nih.gov/pmc/articles/PMC7463323/
  197. journals.plos.org journals.plos.org
    Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
    1
    1. scibot 25 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1371/journal.pbio.3000606

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    journals.plos.org/plosbiology/article
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.56913

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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  199. www.sciencedirect.com www.sciencedirect.com
    Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107894

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    sciencedirect.com/science/article/pii/S2211124720308755
  200. journals.plos.org journals.plos.org
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
    1
    1. scibot 23 Sep 2020
      Addgene_52961

      DOI: 10.1371/journal.ppat.1008507

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    journals.plos.org/plospathogens/article
  201. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Reticulon-3 modulates the incorporation of replication competent hepatitis C virus molecules for release inside infectious exosomes
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1371/journal.pone.0239153

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    pubmed.ncbi.nlm.nih.gov/32941510/
  202. www.sciencedirect.com www.sciencedirect.com
    Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria
    1
    1. scibot 17 Sep 2020
      plasmid_52961

      DOI: 10.1016/j.devcel.2020.02.011

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    sciencedirect.com/science/article/pii/S1534580720301076
  203. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2020.03.010

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    sciencedirect.com/science/article/pii/S1097276520301581
  204. www.sciencedirect.com www.sciencedirect.com
    Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.02.023

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    sciencedirect.com/science/article/pii/S2211124720301777
  205. www.sciencedirect.com www.sciencedirect.com
    A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107995

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    sciencedirect.com/science/article/pii/S2211124720309803
  206. www.sciencedirect.com www.sciencedirect.com
    DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex
    1
    1. scibot 16 Sep 2020
      plasmid_52961

      DOI: 10.1016/j.molcel.2020.03.024

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    sciencedirect.com/science/article/pii/S1097276520301921
  207. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.58828

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    elifesciences.org/articles/58828
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.00352

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    ncbi.nlm.nih.gov/pmc/articles/PMC7076137/
  209. www.sciencedirect.com www.sciencedirect.com
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
    1
    1. scibot 16 Sep 2020
      Addgene_52961

      DOI: 10.1016/j.celrep.2020.107895

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    sciencedirect.com/science/article/pii/S2211124720308767
  210. elifesciences.org elifesciences.org
    Parvovirus Minute Virus of Mice Interacts with Sites of Cellular DNA Damage to Establish and Amplify its Lytic Infection
    1
    1. scibot 15 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.37750

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    elifesciences.org/articles/37750
  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells
    1
    1. scibot 15 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.58504

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    ncbi.nlm.nih.gov/pmc/articles/PMC7473771/
  212. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.00365

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    frontiersin.org/article/10.3389/fimmu.2020.00365/full
  213. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.02.007

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    sciencedirect.com/science/article/pii/S1934590920300606
  214. academic.oup.com academic.oup.com
    Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed-Sternberg cells
    1
    1. scibot 13 Sep 2020
      plasmid_52961

      DOI: 10.1093/carcin/bgaa032

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgaa032/5817053
  215. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B cell lymphoma
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1111/vco.12602

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    onlinelibrary.wiley.com/doi/10.1111/vco.12602
  216. www.sciencedirect.com www.sciencedirect.com
    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
    1
    1. scibot 12 Sep 2020
      plasmid_52961

      DOI: 10.1016/j.cmet.2020.02.001

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    sciencedirect.com/science/article/pii/S1550413120300590