1,029 Matching Annotations
  1. Aug 2021
  2. academic.oup.com academic.oup.com
    Androgen signaling connects short isoform production to breakpoint formation at Ewing sarcoma breakpoint region 1
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    1. scibot 17 Aug 2021
      plasmid_52961

      DOI: 10.1093/narcan/zcab033

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    academic.oup.com/narcancer/article/3/3/zcab033/6352433
  3. 52.53.155.43 52.53.155.43
    Treatment of RB1-intact hepatocellular carcinoma with CDK4/6 inhibitor combination therapy
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    1. scibot 16 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1002/hep.31872

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    52.53.155.43/d535e061bd39448f0bff90d2d8bad0476300ef0d/hep.31872 (1)-html.html
  4. 52.53.155.43 52.53.155.43
    hep.31872-html.html
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    1. scibot 16 Aug 2021
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      DOI: 10.1002/HEP.31872

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    52.53.155.43/9141f02023b9cd2a20a0ded8540f4e4d455d9808/hep.31872-html.html
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
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    1. scibot 15 Aug 2021
      RRID:Addgene_52961

      DOI: 10.7554/eLife.66524

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    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA m6A reader YTHDF2 maintains oncogene expression and is a targetable dependency in glioblastoma stem cells
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    1. scibot 15 Aug 2021
      Addgene_52961

      DOI: 10.1158/2159-8290.CD-20-0331

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    ncbi.nlm.nih.gov/pmc/articles/PMC8110214/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
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    1. scibot 15 Aug 2021
      plasmid_52961

      DOI: 10.1158/2159-8290.CD-20-0775

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858242/
  8. www.sciencedirect.com www.sciencedirect.com
    RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
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    1. scibot 14 Aug 2021
      addgene_52961

      DOI: 10.1016/j.celrep.2021.109451

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    sciencedirect.com/science/article/pii/S2211124721008688
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    Identification of novel TGF-β regulated genes with pro-migratory roles
    1
    1. scibot 14 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.bbadis.2019.165537

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    sciencedirect.com/science/article/pii/S0925443919302601
  10. www.biorxiv.org www.biorxiv.org
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    1. scibot 13 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1101/633685

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    biorxiv.org/content/10.1101/633685v1
  11. www.sciencedirect.com www.sciencedirect.com
    Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
    1
    1. scibot 13 Aug 2021
      Addgene_52961

      DOI: 10.1016/j.cels.2019.04.001

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    sciencedirect.com/science/article/pii/S2405471219301176
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions
    1
    1. scibot 13 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.devcel.2017.12.012

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    ncbi.nlm.nih.gov/pmc/articles/PMC6421364/
  13. www.sciencedirect.com www.sciencedirect.com
    Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor
    1
    1. scibot 11 Aug 2021
      Plasmid_52961

      DOI: 10.1016/j.cell.2016.09.026

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    sciencedirect.com/science/article/pii/S0092867416313083
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 11 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.celrep.2018.09.045

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    ncbi.nlm.nih.gov/pmc/articles/PMC6338448/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 11 Aug 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2018.11.035

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    ncbi.nlm.nih.gov/pmc/articles/PMC6342284/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 09 Aug 2021
      Addgene_52961

      DOI: 10.7554/eLife.39030

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    ncbi.nlm.nih.gov/pmc/articles/PMC6251623/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large parental differences in chromatin organization in pancreatic beta cell line explaining diabetes susceptibility effects
    1
    1. scibot 06 Aug 2021
      Addgene catalog no. 52961

      DOI: 10.1038/s41467-021-24635-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC8282625/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 06 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.molcel.2017.04.027

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    ncbi.nlm.nih.gov/pmc/articles/PMC5446411/
  19. elifesciences.org elifesciences.org
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    1. scibot 06 Aug 2021
      plasmid_52961

      DOI: 10.7554/eLife.31023

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    elifesciences.org/articles/31023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
    1
    1. scibot 06 Aug 2021
      RRID:Addgene_52961

      DOI: 10.26508/lsa.202000875

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321670/
  21. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 05 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.ccell.2018.11.006

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    sciencedirect.com/science/article/pii/S1535610818305270
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 05 Aug 2021
      Plasmid_52961

      DOI: 10.1016/j.cmet.2018.07.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC6224545/
  23. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 05 Aug 2021
      Addgene_52961

      DOI: 10.1016/j.cell.2018.11.038

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    sciencedirect.com/science/article/pii/S0092867418315630
  24. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
    1
    1. scibot 04 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.chom.2018.11.001

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    sciencedirect.com/science/article/pii/S1931312818305584
  25. www.sciencedirect.com www.sciencedirect.com
    Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity
    1
    1. scibot 03 Aug 2021
      plasmid_52961

      DOI: 10.1016/j.ebiom.2021.103505

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    sciencedirect.com/science/article/pii/S235239642100298X
  26. www.nature.com www.nature.com
    Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma
    1
    1. scibot 02 Aug 2021
      Plasmid_52961

      DOI: 10.1038/s41467-018-05029-3

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    nature.com/articles/s41467-018-05029-3
  27. Jul 2021
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 31 Jul 2021
      plasmid_52961

      DOI: 10.7554/eLife.41913

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    ncbi.nlm.nih.gov/pmc/articles/PMC6336405/
  29. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 31 Jul 2021
      Plasmid_52961

      DOI: 10.1016/j.cmet.2018.12.020

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    sciencedirect.com/science/article/pii/S1550413118307575
  30. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux
    1
    1. scibot 30 Jul 2021
      pLentiCRISPR v2

      DOI: 10.1016/j.molcel.2019.07.021

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    sciencedirect.com/science/article/pii/S1097276519305519
  31. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening
    1
    1. scibot 30 Jul 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2016.12.021

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    sciencedirect.com/science/article/pii/S1097276516308644
  32. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 30 Jul 2021
      Plasmid_52961

      DOI: 10.1016/j.celrep.2018.09.071

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    sciencedirect.com/science/article/pii/S2211124718315316
  33. www.sciencedirect.com www.sciencedirect.com
    Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing
    1
    1. scibot 29 Jul 2021
      RRID: Addgene_52961

      DOI: 10.1016/j.celrep.2019.08.060

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    sciencedirect.com/science/article/pii/S2211124719311088
  34. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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    1. scibot 29 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2019.06.014

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    sciencedirect.com/science/article/pii/S0092867419306774
  35. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
    1. scibot 29 Jul 2021
      RRID: Addgene_52961

      DOI: 10.1016/j.molcel.2019.05.030

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    sciencedirect.com/science/article/pii/S1097276519304022
  36. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 29 Jul 2021
      lenti-CRISPRv2

      DOI: 10.1016/j.celrep.2019.07.027

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    sciencedirect.com/science/article/pii/S2211124719309246
  37. www.sciencedirect.com www.sciencedirect.com
    Functional Relevance of Interleukin-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
    1
    1. scibot 29 Jul 2021
      lentiCRISPRv2

      DOI: 10.1016/j.str.2019.05.011

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    sciencedirect.com/science/article/pii/S096921261930173X
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 29 Jul 2021
      plasmid_52961

      DOI: 10.1016/j.molcel.2017.07.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC5562512/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 29 Jul 2021
      plasmid_52961

      DOI: 10.1038/s41421-018-0068-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC6312541/
  40. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 29 Jul 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124718317984
  41. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
    1
    1. scibot 28 Jul 2021
      Addgene#52961

      DOI: 10.1016/j.immuni.2019.01.007

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    sciencedirect.com/science/article/pii/S1074761319300305
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 28 Jul 2021
      Plasmid_52961

      DOI: 10.1038/s41467-018-07402-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC6283830/
  43. www.sciencedirect.com www.sciencedirect.com
    Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
    1
    1. scibot 27 Jul 2021
      52961

      DOI: 10.1016/j.celrep.2018.10.100

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    sciencedirect.com/science/article/pii/S2211124718317224
  44. www.sciencedirect.com www.sciencedirect.com
    Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS
    1
    1. scibot 27 Jul 2021
      52961

      DOI: 10.1016/j.cels.2018.10.010

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    sciencedirect.com/science/article/pii/S2405471218304356
  45. rupress.org rupress.org
    A BLOC-1–AP-3 super-complex sorts a cis-SNARE complex into endosome-derived tubular transport carriers
    1
    1. scibot 23 Jul 2021
      Addgene_52961

      DOI: 10.1083/jcb.202005173

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    rupress.org/jcb/article/220/7/e202005173/212016/A-BLOC-1-AP-3-super-complex-sorts-a-cis-SNARE
  46. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
    1
    1. scibot 22 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2021.06.016

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    sciencedirect.com/science/article/pii/S153561082100338X
  47. www.sciencedirect.com www.sciencedirect.com
    Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer
    1
    1. scibot 22 Jul 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124721007920
  48. www.nature.com www.nature.com
    The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases
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    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41420-021-00539-4

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    nature.com/articles/s41420-021-00539-4
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of immune cell reactivity with cis-binding Siglec agonists
    1
    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1073/pnas.2012408118

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    ncbi.nlm.nih.gov/pmc/articles/PMC7826350/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity
    1
    1. scibot 14 Jul 2021
      Plasmid_52961

      DOI: 10.1016/j.cell.2019.01.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC8274936/
  51. www.sciencedirect.com www.sciencedirect.com
    BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells
    1
    1. scibot 14 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109359

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    sciencedirect.com/science/article/pii/S2211124721007579
  52. www.sciencedirect.com www.sciencedirect.com
    MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development
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    1. scibot 14 Jul 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109390

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    sciencedirect.com/science/article/pii/S2211124721007889
  53. www.sciencedirect.com www.sciencedirect.com
    Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models
    1
    1. scibot 13 Jul 2021
      RRID:Addgene_529

      DOI: 10.1016/j.xpro.2021.100668

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    sciencedirect.com/science/article/pii/S2666166721003750
  54. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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      Cat# 52961

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00493-7
  55. Jun 2021
  56. bloodcancerdiscov.aacrjournals.org bloodcancerdiscov.aacrjournals.org
    SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
    1
    1. scibot 29 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1158/2643-3230.BCD-20-0168

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  57. www.sciencedirect.com www.sciencedirect.com
    The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
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    sciencedirect.com/science/article/pii/S1535610821002865
  58. www.cmghjournal.org www.cmghjournal.org
    Sestrin proteins protect against lipotoxicity-induced oxidative stress in the liver via suppression of c-Jun N-terminal kinases: Short title: Sestrins ameliorate hepatic lipotoxicity
    1
    1. scibot 25 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.jcmgh.2021.04.015

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    cmghjournal.org/article/S2352-345X(21)00086-2/abstract
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA
    1
    1. scibot 17 Jun 2021
      RRID:Addgene_52961

      DOI: 10.1158/2643-3230.bcd-20-0168

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    ncbi.nlm.nih.gov/pmc/articles/PMC8133360/
  60. www.cell.com www.cell.com
    STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.ccell.2021.05.007

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    cell.com/cancer-cell/fulltext/S1535-6108(21)00273-7
  61. May 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
    1
    1. scibot 27 May 2021
      Addgene_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC8139829/
  63. www.cell.com www.cell.com
    TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis
    1
    1. scibot 20 May 2021
      Cat# 52961

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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00223-0
  64. www.sciencedirect.com www.sciencedirect.com
    Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage
    1
    1. scibot 15 May 2021
      Cat# 52961

      DOI: 10.1016/j.immuni.2020.06.007

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    sciencedirect.com/science/article/pii/S1074761320302375
  65. www.nature.com www.nature.com
    YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
    1
    1. scibot 15 May 2021
      Addgene_52961

      DOI: 10.1038/s41467-021-22987-3

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    nature.com/articles/s41467-021-22987-3
  66. www.sciencedirect.com www.sciencedirect.com
    Rab34 is necessary for early stages of intracellular ciliogenesis
    1
    1. scibot 14 May 2021
      plasmid_52961

      DOI: 10.1016/j.cub.2021.04.018

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    sciencedirect.com/science/article/pii/S0960982221005315
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Giantin is required for intracellular N-terminal processing of type I procollagen
    1
    1. scibot 12 May 2021
      plasmid_52961

      DOI: 10.1083/jcb.202005166

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    ncbi.nlm.nih.gov/pmc/articles/PMC8103548/
  68. jvi.asm.org jvi.asm.org
    Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation
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    1. scibot 11 May 2021
      RRID:Addgene_52961

      DOI: 10.1128/JVI.00453-21

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    jvi.asm.org/content/95/11/e00453-21
  69. www.eneuro.org www.eneuro.org
    FEZ1 forms complexes with CRMP1 and DCC to regulate axon and dendrite development
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    1. scibot 10 May 2021
      RRID:Addgene_52961

      DOI: 10.1523/ENEURO.0193-20.2021

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    eneuro.org/content/8/2/ENEURO.0193-20.2021
  70. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Follicular lymphoma-associated BTK mutations are inactivating resulting in augmented AKT activation
    1
    1. scibot 10 May 2021
      Addgene_52961

      DOI: 10.1158/1078-0432.CCR-20-3741

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    clincancerres.aacrjournals.org/content/27/8/2301
  71. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
    1
    1. scibot 09 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.09.019

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    sciencedirect.com/science/article/pii/S193459092030494X
  72. www.sciencedirect.com www.sciencedirect.com
    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
    1
    1. scibot 09 May 2021
      Addgene_52961

      DOI: 10.1016/j.stem.2020.12.008

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    sciencedirect.com/science/article/pii/S1934590920305920
  73. www.sciencedirect.com www.sciencedirect.com
    Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells
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    1. scibot 09 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.12.009

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    sciencedirect.com/science/article/pii/S1934590920305932
  74. www.sciencedirect.com www.sciencedirect.com
    Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency
    1
    1. scibot 08 May 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2021.01.019

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    sciencedirect.com/science/article/pii/S1097276521000393
  75. www.sciencedirect.com www.sciencedirect.com
    LRRC8A:C/E Heteromeric Channels Are Ubiquitous Transporters of cGAMP
    1
    1. scibot 08 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2020.10.021

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  76. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    1. scibot 07 May 2021
      plasmid_52961

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  77. jasn.asnjournals.org jasn.asnjournals.org
    SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance
    1
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      RRID:Addgene_52961

      DOI: 10.1681/ASN.2020081126

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    jasn.asnjournals.org/content/32/3/563
  78. www.sciencedirect.com www.sciencedirect.com
    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
    1
    1. scibot 07 May 2021
      Addgene_52961

      DOI: 10.1016/j.molcel.2020.05.011

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  79. www.sciencedirect.com www.sciencedirect.com
    3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
    1
    1. scibot 06 May 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2021.02.017

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    sciencedirect.com/science/article/pii/S153458072100157X
  80. www.sciencedirect.com www.sciencedirect.com
    Pancreatic Cancer Cells Require the Transcription Factor MYRF to Maintain ER Homeostasis
    2
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      Cat#52961

      DOI: 10.1016/j.devcel.2020.09.011

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      Addgene_52961

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    sciencedirect.com/science/article/pii/S1534580720307139
  81. www.sciencedirect.com www.sciencedirect.com
    The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis
    1
    1. scibot 05 May 2021
      Plasmid_52961

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    sciencedirect.com/science/article/pii/S1534580720306675
  82. www.sciencedirect.com www.sciencedirect.com
    Glutamine Metabolism Controls Chondrocyte Identity and Function
    1
    1. scibot 04 May 2021
      Addgene plasmid repository #52961

      DOI: 10.1016/j.devcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1534580720303579
  83. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism
    1
    1. scibot 04 May 2021
      plasmid_52961

      DOI: 10.1016/j.jlr.2021.100082

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    sciencedirect.com/science/article/pii/S002222752100064X
  84. www.sciencedirect.com www.sciencedirect.com
    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
    1
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      Cat#52961

      DOI: 10.1016/j.cmet.2021.03.003

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    sciencedirect.com/science/article/pii/S1550413121001108
  85. Apr 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans
    1
    1. scibot 30 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.cmet.2020.10.020

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    sciencedirect.com/science/article/pii/S1550413120305532
  87. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identifies Metabolic Vulnerabilities in Pancreatic Cancer
    1
    1. scibot 29 Apr 2021
      plasmid_52961

      DOI: 10.1016/j.cmet.2020.10.018

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    sciencedirect.com/science/article/pii/S1550413120305519
  88. www.sciencedirect.com www.sciencedirect.com
    Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
    1
    1. scibot 28 Apr 2021
      Addgene_52961

      DOI: 10.1016/j.chom.2020.05.012

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    sciencedirect.com/science/article/pii/S1931312820302948
  89. www.sciencedirect.com www.sciencedirect.com
    Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability
    1
    1. scibot 28 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.chom.2020.05.011

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    sciencedirect.com/science/article/pii/S1931312820302936
  90. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
    1
    1. scibot 28 Apr 2021
      Plasmid_52961

      DOI: 10.1016/j.celrep.2021.109013

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    sciencedirect.com/science/article/pii/S2211124721003272
  91. www.sciencedirect.com www.sciencedirect.com
    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
    1
    1. scibot 24 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.10.046

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    sciencedirect.com/science/article/pii/S0092867420314537
  92. www.sciencedirect.com www.sciencedirect.com
    A Genetic Map of the Response to DNA Damage in Human Cells
    1
    1. scibot 23 Apr 2021
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    sciencedirect.com/science/article/pii/S0092867420306735
  93. www.sciencedirect.com www.sciencedirect.com
    MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway
    1
    1. scibot 22 Apr 2021
      Plasmid Cat#52961

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    sciencedirect.com/science/article/pii/S1535610820305961
  94. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1
    1
    1. scibot 21 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2021.109010

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    sciencedirect.com/science/article/pii/S2211124721003247
  95. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
    1
    1. scibot 17 Apr 2021
      Cat# 52961

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    sciencedirect.com/science/article/pii/S1535610820302154
  96. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    1. scibot 17 Apr 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S1535610820302750
  97. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
    1
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      Addgene_52961

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    sciencedirect.com/science/article/pii/S1535610820302130
  98. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S109727652100229X
  99. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
      Plasmid_52961

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  100. www.sciencedirect.com www.sciencedirect.com
    Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation
    1
    1. scibot 12 Apr 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2451945621000519
  101. www.sciencedirect.com www.sciencedirect.com
    PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis
    1
    1. scibot 12 Apr 2021
      plasmid_52961

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    sciencedirect.com/science/article/pii/S1097276521000873
  102. journals.plos.org journals.plos.org
    Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection
    1
    1. scibot 06 Apr 2021
      RRID:Addgene_52961

      DOI: 10.1371/journal.ppat.1009491

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    journals.plos.org/plospathogens/article
  103. Mar 2021
  104. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
    1
    1. scibot 24 Mar 2021
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124721001972
  105. www.sciencedirect.com www.sciencedirect.com
    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
    1
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      52961

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    sciencedirect.com/science/article/pii/S2211124721001546
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model
    1
    1. scibot 10 Mar 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41598-021-84270-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC7933353/
  107. www.sciencedirect.com www.sciencedirect.com
    The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses
    1
    1. scibot 08 Mar 2021
      Plasmid_52961

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    sciencedirect.com/science/article/pii/S1074761320304684
  108. www.sciencedirect.com www.sciencedirect.com
    Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling
    1
    1. scibot 03 Mar 2021
      Cat#52961

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    sciencedirect.com/science/article/pii/S2211124721000735
  109. www.frontiersin.org www.frontiersin.org
    Novel Secreted Protein of Mycoplasma bovis MbovP280 Induces Macrophage Apoptosis Through CRYAB
    1
    1. scibot 03 Mar 2021
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2021.619362

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    frontiersin.org/article/10.3389/fimmu.2021.619362/full
  110. Feb 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Reticulon-3 Promotes Endosome Maturation at ER Membrane Contact Sites
    1
    1. scibot 28 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.devcel.2020.12.014

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    sciencedirect.com/science/article/pii/S1534580720310200
  112. www.pnas.org www.pnas.org
    The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6
    1
    1. scibot 27 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1073/pnas.2015887118

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    pnas.org/content/118/1/e2015887118
  113. www.nature.com www.nature.com
    Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41467-020-17089-5

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    nature.com/articles/s41467-020-17089-5
  114. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 expression in advanced prostate cancer and response to platinum-based chemotherapy
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1158/1535-7163.MCT-19-0926

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    mct.aacrjournals.org/content/19/5/1157
  115. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteasome inhibitors and Smac mimetics cooperate to induce cell death in Diffuse Large B‐cell Lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis
    1
    1. scibot 25 Feb 2021
      Addgene_52961

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32976
  116. journals.sagepub.com journals.sagepub.com
    A genome-wide CRISPR screen identifies regulation factors of the TLR3 signalling pathway - Laurent Zablocki-Thomas, Sam A Menzies, Paul J Lehner, Nicolas Manel, Philippe Benaroch,
    1
    1. scibot 25 Feb 2021
      plasmid_52961

      DOI: 10.1177/1753425920915507

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    journals.sagepub.com/doi/full/10.1177/1753425920915507
  117. www.nature.com www.nature.com
    Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages
    1
    1. scibot 25 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1038/s41598-021-82137-z

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    nature.com/articles/s41598-021-82137-z
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RB1 Deletion in Retinoblastoma Protein Pathway-Disrupted Cells Results in DNA Damage and Cancer Progression
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52961

      DOI: 10.1128/MCB.00105-19

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    ncbi.nlm.nih.gov/pmc/articles/PMC6664603/
  119. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 24 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  120. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.12.005

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    cell.com/cell/abstract/S0092-8674(20)31627-5
  121. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
    1
    1. scibot 24 Feb 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2021.108749

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    sciencedirect.com/science/article/pii/S2211124721000620
  122. www.sciencedirect.com www.sciencedirect.com
    High-Throughput Screens of PAM-Flexible Cas9 Variants for Gene Knockout and Transcriptional Modulation
    1
    1. scibot 13 Feb 2021
      plasmid_52961

      DOI: 10.1016/j.celrep.2020.02.010

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    sciencedirect.com/science/article/pii/S2211124720301649
  123. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
    1
    1. scibot 11 Feb 2021
      Plasmid_52961

      DOI: 10.1016/j.ccell.2020.03.001

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    sciencedirect.com/science/article/pii/S153561082030101X
  124. www.sciencedirect.com www.sciencedirect.com
    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
    1
    1. scibot 11 Feb 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2020.02.063

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    sciencedirect.com/science/article/pii/S221112472030231X
  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy
    1
    1. scibot 09 Feb 2021
      RRID:Addgene_52961

      DOI: 10.3389/fmicb.2020.613963

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    ncbi.nlm.nih.gov/pmc/articles/PMC7862720/
  126. Jan 2021
  127. www.sciencedirect.com www.sciencedirect.com
    Optimized protocol for gene editing in adipocytes using CRISPR-Cas9 technology
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.xpro.2021.100307

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    sciencedirect.com/science/article/pii/S2666166721000149
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.cell.2020.12.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7796900/
  129. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    1
    1. scibot 27 Jan 2021
      Addgene_52961

      DOI: 10.1016/j.stem.2020.03.016

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    sciencedirect.com/science/article/pii/S1934590920301387
  130. www.sciencedirect.com www.sciencedirect.com
    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis
    1
    1. scibot 16 Jan 2021
      Addgene_52961

      DOI: 10.1016/j.celrep.2020.107667

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    sciencedirect.com/science/article/pii/S2211124720306203
  131. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 15 Jan 2021
      plasmid_52961

      DOI: 10.1016/j.cell.2020.05.053

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    sciencedirect.com/science/article/pii/S0092867420306863
  132. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Addgene_52961

      DOI: 10.1016/j.chom.2020.04.024

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    sciencedirect.com/science/article/pii/S1931312820302511
  133. www.sciencedirect.com www.sciencedirect.com
    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
    1
    1. scibot 08 Jan 2021
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.108586

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    sciencedirect.com/science/article/pii/S2211124720315758
  134. Dec 2020
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes
    1
    1. scibot 25 Dec 2020
      RRID:Addgene_52961

      DOI: 10.1128/IAI.00017-20

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    ncbi.nlm.nih.gov/pmc/articles/PMC7309616/
  136. www.sciencedirect.com www.sciencedirect.com
    FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells
    1
    1. scibot 24 Dec 2020
      lentiCRISPR v2

      DOI: 10.1016/j.cub.2020.11.052

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    sciencedirect.com/science/article/pii/S0960982220317656
  137. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      Addgene_52961

      DOI: 10.1016/j.molcel.2020.12.006

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  138. www.cell.com www.cell.com
    Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors
    1
    1. scibot 11 Dec 2020
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    cell.com/developmental-cell/fulltext/S1534-5807(20)30794-2
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
    1
    1. scibot 09 Dec 2020
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  140. www.nature.com www.nature.com
    Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria
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      DOI: 10.1038/s41419-020-03220-3

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  141. Nov 2020
  142. www.nature.com www.nature.com
    Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
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  145. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cutibacterium acnes Infection Induces Type I Interferon Synthesis Through the cGAS-STING Pathway
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    1. scibot 12 Nov 2020
      plasmid_52961

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  147. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
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      LentiCRISPRv2

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    sciencedirect.com/science/article/pii/S0092867420313921
  148. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
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  149. Oct 2020
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ovarian cancer cells direct monocyte differentiation through a non-canonical pathway
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    1. scibot 24 Oct 2020
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7568422/
  151. www.nature.com www.nature.com
    ERK3/MAPK6 is required for KRAS-mediated NSCLC tumorigenesis
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation
    1
    1. scibot 14 Oct 2020
      plasmid_52961

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    ncbi.nlm.nih.gov/pmc/articles/PMC7545232/
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
    1. scibot 13 Oct 2020
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      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  154. www.frontiersin.org www.frontiersin.org
    Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
    1
    1. scibot 09 Oct 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.565924

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    frontiersin.org/article/10.3389/fimmu.2020.565924/full
  155. Sep 2020
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linker histone H1.2 and H1.4 affect the neutrophil lineage determination
    1
    1. scibot 26 Sep 2020
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      DOI: 10.7554/eLife.52563

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    ncbi.nlm.nih.gov/pmc/articles/PMC7250579/
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1002/1878-0261.12753

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    ncbi.nlm.nih.gov/pmc/articles/PMC7463323/
  158. journals.plos.org journals.plos.org
    Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells
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    1. scibot 25 Sep 2020
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      DOI: 10.1371/journal.pbio.3000606

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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.56913

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  160. www.sciencedirect.com www.sciencedirect.com
    Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells
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      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S2211124720308755
  161. journals.plos.org journals.plos.org
    TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
    1
    1. scibot 23 Sep 2020
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    journals.plos.org/plospathogens/article
  162. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Reticulon-3 modulates the incorporation of replication competent hepatitis C virus molecules for release inside infectious exosomes
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1371/journal.pone.0239153

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  163. www.sciencedirect.com www.sciencedirect.com
    Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria
    1
    1. scibot 17 Sep 2020
      plasmid_52961

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    sciencedirect.com/science/article/pii/S1534580720301076
  164. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
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    1. scibot 17 Sep 2020
      RRID:Addgene_52961

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    sciencedirect.com/science/article/pii/S1097276520301581
  165. www.sciencedirect.com www.sciencedirect.com
    Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.02.023

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    sciencedirect.com/science/article/pii/S2211124720301777
  166. www.sciencedirect.com www.sciencedirect.com
    A Switch in p53 Dynamics Marks Cells That Escape from DSB-Induced Cell Cycle Arrest
    1
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      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107995

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    sciencedirect.com/science/article/pii/S2211124720309803
  167. www.sciencedirect.com www.sciencedirect.com
    DNA Methylation Regulates Alternative Polyadenylation via CTCF and the Cohesin Complex
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      plasmid_52961

      DOI: 10.1016/j.molcel.2020.03.024

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  168. elifesciences.org elifesciences.org
    EDF1 coordinates cellular responses to ribosome collisions
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    1. scibot 16 Sep 2020
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      DOI: 10.7554/eLife.58828

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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dengue Virus Serotype 2 and Its Non-Structural Proteins 2A and 2B Activate NLRP3 Inflammasome
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      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.00352

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  170. www.sciencedirect.com www.sciencedirect.com
    Ribosome Recycling by ABCE1 Links Lysosomal Function and Iron Homeostasis to 3ʹ UTR-Directed Regulation and Nonsense-Mediated Decay
    1
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      Addgene_52961

      DOI: 10.1016/j.celrep.2020.107895

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  171. elifesciences.org elifesciences.org
    Parvovirus Minute Virus of Mice Interacts with Sites of Cellular DNA Damage to Establish and Amplify its Lytic Infection
    1
    1. scibot 15 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.37750

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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells
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    1. scibot 15 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.58504

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  173. www.frontiersin.org www.frontiersin.org
    A20 Restricts Inflammatory Response and Desensitizes Gingival Keratinocytes to Apoptosis
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_52961

      DOI: 10.3389/fimmu.2020.00365

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  174. www.sciencedirect.com www.sciencedirect.com
    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2020.02.007

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  175. academic.oup.com academic.oup.com
    Mitochondrial DNA mutations induce mitochondrial biogenesis and increase the tumorigenic potential of Hodgkin and Reed-Sternberg cells
    1
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      plasmid_52961

      DOI: 10.1093/carcin/bgaa032

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    academic.oup.com/carcin/carcin/advance-article-abstract/doi/10.1093/carcin/bgaa032/5817053
  176. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Optimization of canine CD20 chimeric antigen receptor T cell manufacturing and in vitro cytotoxic activity against B cell lymphoma
    1
    1. scibot 13 Sep 2020
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      DOI: 10.1111/vco.12602

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    onlinelibrary.wiley.com/doi/10.1111/vco.12602
  177. www.sciencedirect.com www.sciencedirect.com
    Bacteria Boost Mammalian Host NAD Metabolism by Engaging the Deamidated Biosynthesis Pathway
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      plasmid_52961

      DOI: 10.1016/j.cmet.2020.02.001

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    sciencedirect.com/science/article/pii/S1550413120300590
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms
    1
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      Addgene_52961

      DOI: 10.1038/s41598-020-68934-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC7376217/
  179. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems
    1
    1. scibot 10 Sep 2020
      plasmid_52961

      DOI: 10.1093/nar/gkaa671

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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Formate induces a metabolic switch in nucleotide and energy metabolism
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    1. scibot 10 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1038/s41419-020-2523-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC7198490/
  181. www.sciencedirect.com www.sciencedirect.com
    Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.stem.2019.11.016

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    sciencedirect.com/science/article/pii/S1934590919304710
  182. elifesciences.org elifesciences.org
    A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
    1
    1. scibot 09 Sep 2020
      Addgene_52961

      DOI: 10.7554/eLife.39823

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    elifesciences.org/articles/39823
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
    1
    1. scibot 09 Sep 2020
      plasmid_52961

      DOI: 10.1016/j.cell.2020.06.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7316060/
  184. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2020.06.039

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    pubmed.ncbi.nlm.nih.gov/32710848/
  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.58041

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    ncbi.nlm.nih.gov/pmc/articles/PMC7470841/
  186. www.jneurosci.org www.jneurosci.org
    Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
    1
    1. scibot 08 Sep 2020
      plasmid_52961

      DOI: 10.1523/JNEUROSCI.2994-18.2019

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    jneurosci.org/content/39/37/7408
  187. journals.plos.org journals.plos.org
    Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1371/journal.ppat.1008646

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    journals.plos.org/plospathogens/article
  188. www.sciencedirect.com www.sciencedirect.com
    Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107531

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    sciencedirect.com/science/article/pii/S2211124720304319
  189. www.sciencedirect.com www.sciencedirect.com
    Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.108068

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    sciencedirect.com/science/article/pii/S2211124720310536
  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells
    1
    1. scibot 07 Sep 2020
      plasmid_52961

      DOI: 10.1126/sciadv.aaz6699

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    ncbi.nlm.nih.gov/pmc/articles/PMC7299619/
  191. www.sciencedirect.com www.sciencedirect.com
    Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling
    1
    1. scibot 07 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.devcel.2020.05.014

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    sciencedirect.com/science/article/pii/S1534580720304032
  192. bioone.org bioone.org
    Endogenous Retrovirus Activation as a Key Mechanism of Anti-Tumor Immune Response in Radiotherapy
    1
    1. scibot 06 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1667/RADE-20-00013

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    bioone.org/journals/radiation-research/volume-193/issue-4/RADE-20-00013/Endogenous-Retrovirus-Activation-as-a-Key-Mechanism-of-Anti-Tumor/10.1667/RADE-20-00013.full
  193. www.sciencedirect.com www.sciencedirect.com
    E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration
    1
    1. scibot 06 Sep 2020
      Plasmid_52961

      DOI: 10.1016/j.devcel.2019.12.016

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    sciencedirect.com/science/article/pii/S1534580719310391
  194. www.mdpi.com www.mdpi.com
    Multiple Functions of Fubp1 in Cell Cycle Progression and Cell Survival
    1
    1. scibot 06 Sep 2020
      RRID:Addgene_52961

      DOI: 10.3390/cells9061347

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    mdpi.com/2073-4409/9/6/1347
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERK3/MAPK6 controls IL-8 production and chemotaxis
    1
    1. scibot 05 Sep 2020
      plasmid_52961

      DOI: 10.7554/eLife.52511

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    ncbi.nlm.nih.gov/pmc/articles/PMC7192585/
  196. www.jbc.org www.jbc.org
    Long noncoding RNA pncRNA-D reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification
    1
    1. scibot 04 Sep 2020
      lenti-CRISPR-v2

      DOI: 10.1074/jbc.RA119.011556

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    jbc.org/content/295/17/5626.full
  197. www.sciencedirect.com www.sciencedirect.com
    Transfer of cGAMP into Bystander Cells via LRRC8 Volume-Regulated Anion Channels Augments STING-Mediated Interferon Responses and Anti-viral Immunity
    1
    1. scibot 04 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.immuni.2020.03.016

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    sciencedirect.com/science/article/pii/S1074761320301291
  198. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 03 Sep 2020
      Addgene Cat#52961

      DOI: 10.1016/j.stem.2020.04.001

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    sciencedirect.com/science/article/pii/S1934590920301405
  199. www.sciencedirect.com www.sciencedirect.com
    FTO Demethylates Cyclin D1 mRNA and Controls Cell-Cycle Progression
    1
    1. scibot 03 Sep 2020
      Addgene, Cat#52961

      DOI: 10.1016/j.celrep.2020.03.028

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    sciencedirect.com/science/article/pii/S2211124720303429
  200. www.sciencedirect.com www.sciencedirect.com
    A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability
    1
    1. scibot 03 Sep 2020
      Addgene52961

      DOI: 10.1016/j.celrep.2020.01.020

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    sciencedirect.com/science/article/pii/S2211124720300292
  201. www.jbc.org www.jbc.org
    Regulation of poly(A)-specific ribonuclease activity by reversible lysine acetylation
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1074/jbc.RA120.012552

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    jbc.org/content/295/30/10255.full
  202. www.sciencedirect.com www.sciencedirect.com
    Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress
    1
    1. scibot 03 Sep 2020
      lentiCRISPR-v2

      DOI: 10.1016/j.cmet.2020.06.002

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    sciencedirect.com/science/article/pii/S155041312030303X
  203. www.sciencedirect.com www.sciencedirect.com
    Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion
    1
    1. scibot 03 Sep 2020
      pLenti-CRISPR v2

      DOI: 10.1016/j.celrep.2020.107879

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    sciencedirect.com/science/article/pii/S2211124720308603
  204. www.sciencedirect.com www.sciencedirect.com
    Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.107994

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    sciencedirect.com/science/article/pii/S2211124720309797
  205. www.sciencedirect.com www.sciencedirect.com
    Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death
    1
    1. scibot 03 Sep 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.celrep.2020.108008

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    sciencedirect.com/science/article/pii/S2211124720309931
  206. Aug 2020
  207. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
    1
    1. scibot 20 Aug 2020
      Addgene ID: 52961

      DOI: 10.1016/j.cell.2020.05.053

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    sciencedirect.com/science/article/pii/S0092867420306863
  208. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2020
      Addgene plasmid # 52961

      DOI: 10.1016/j.ccell.2019.12.002

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    sciencedirect.com/science/article/pii/S1535610819305720
  209. Jan 2020
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1182/bloodadvances.2018029546

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    ncbi.nlm.nih.gov/pmc/articles/PMC6650741/
  211. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Domain‐specific CD6 monoclonal antibodies identify CD6 isoforms generated by alternative‐splicing
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1111/imm.13087

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    onlinelibrary.wiley.com/doi/abs/10.1111/imm.13087
  212. www.sciencedirect.com www.sciencedirect.com
    PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.1016/j.molcel.2019.05.030

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    sciencedirect.com/science/article/pii/S1097276519304022
  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52961

      DOI: 10.7554/eLife.47498

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    ncbi.nlm.nih.gov/pmc/articles/PMC6739868/