After all, the rise in antibiotic resistance doesn’t mean that we shouldn’t have invented antibiotics at all.

indicate that even low concentrations of just a single type of antibiotic leads to resistance to multiple classes of antibiotics.

Overall, the low contamination level of antibiotics and high absolute abundance of ARGs indicated that ARGs previously introduced to an environment can self-amplify and persist in the environment

suggesting that STPs have become an important source of contamination for their receiving rivers

Additionally, the concentrations of antibiotics and the abundance of ARGs might increase after the sewage treatment process.

wastewater treatment plants are hotspots for the release of antibiotics, and transmission of diverse antibiotic resistance bacteria (ARB) as well as ARGs into various environments

Recent findings have indicated that most ARGs could not be efficiently removed by traditional anaerobic digestion treatment

introduction of Cu to agricultural soil selects for Cu resistance, but also indirectly selects for antibiotic resistance in the Cu‐resistant bacteria