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  1. Sep 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAINS in the Assay: Chemical Mechanisms of Assay Interference and Promiscuous Enzymatic Inhibition Observed during a Sulfhydryl-Scavenging HTS
    1
    1. zhentg 19 Sep 2021

      this paper described some hit compounds that interfere with the assay components. some compounds react with thiol, and their SAR is reported.

      PAINS covalent warhead
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    ncbi.nlm.nih.gov/pmc/articles/PMC4360378/
  3. Nov 2020
  4. www.scripps.edu www.scripps.edu
    The Cravatt Lab
    1
    1. zhentg 13 Nov 2020
      Journal of the American Chemical Society. 2018, 140, 8069-8073.

      covalent warhead

      covalent warhead
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    scripps.edu/cravatt/refs.html