Secunda via est ex ratione causae efficientis. Invenimus enim in istis sensibilibus esse ordinem causarum efficientium, nec tamen invenitur, nec est possibile, quod aliquid sit causa efficiens sui ipsius; quia sic esset prius seipso, quod est impossibile. Non autem est possibile quod in causis efficientibus procedatur in infinitum. Quia in omnibus causis efficientibus ordinatis, primum est causa medii, et medium est causa ultimi, sive media sint plura sive unum tantum, remota autem causa, removetur effectus, ergo, si non fuerit primum in causis efficientibus, non erit ultimum nec medium. Sed si procedatur in infinitum in causis efficientibus, non erit prima causa efficiens, et sic non erit nec effectus ultimus, nec causae efficientes mediae, quod patet esse falsum. Ergo est necesse ponere aliquam causam efficientem primam, quam omnes Deum nominant.

In the world of sense we find there is an order of efficient causes. There is no case known (neither is it, indeed, possible) in which a thing is found to be the efficient cause of itself; for so it would be prior to itself, which is impossible. Now in efficient causes it is not possible to go on to infinity, because in all efficient causes following in order, the first is the cause of the intermediate cause, and the intermediate is the cause of the ultimate cause, whether the intermediate cause be several, or only one. Now to take away the cause is to take away the effect. Therefore, if there be no first cause among efficient causes, there will be no ultimate, nor any intermediate cause. But if in efficient causes it is possible to go on to infinity, there will be no first efficient cause, neither will there be an ultimate effect, nor any intermediate efficient causes; all of which is plainly false. Therefore it is necessary to admit a first efficient cause, to which everyone gives the name of God.

εἰ δὴ ἀνάγκη πᾶν τὸ κινούμενον ὑπό τινός τε κινεῖσθαι, καὶ ἢ ὑπὸ κινουμένου ὑπ' ἄλλου ἢ μή, καὶ εἰ μὲν ὑπ' ἄλλου [κινουμένου], ἀνάγκη τι εἶναι κινοῦν ὃ οὐχ ὑπ' ἄλλου πρῶτον, εἰ δὲ τοιοῦτο τὸ πρῶτον, οὐκ ἀνάγκη θάτερον (ἀδύνατον γὰρ εἰς ἄπειρον ἰέναι τὸ κινοῦν καὶ κινούμενον ὑπ' ἄλλου αὐτό· τῶν γὰρ ἀπείρων οὐκ ἔστιν οὐδὲν πρῶτον)—εἰ οὖν ἅπαν μὲν τὸ κινούμενον ὑπό τινος κινεῖται, τὸ δὲ πρῶτον κινοῦν κινεῖται μέν, οὐχ ὑπ' ἄλλου δέ, ἀνάγκη αὐτὸ ὑφ' αὑτοῦ κινεῖσθαι.