74 Matching Annotations
  1. Jul 2020
    1. We analyzed magnetic resonance imaging (MRI) data from a large longitudinal sample (270 participants, 678 scans) using an automated segmentation tool and mixed models to delineate the development of hippocampal subregion volumes from childhood to adulthood.
    1. average neuronal density of the same 60 loci was significantly higher in the male group than in the female group, and the corresponding mean male-to-female ratios were 1.18 in the right and 1.13

      neuronal density difference

    2. cortical thickness of the 60 loci examined was similar in males and females

      No Thickness difference

  2. Apr 2018
    1. The age, MMSE, HAMD,and HAMA were performed with independent samples T test, and sex was performed with Chi-Square test.

      Stat method

    2. Significant difference was set at a P value of <0.05

      stat threshold

    3. PASW Statistics 18.0

      stat tool

    4. ITK-SNAP (V3.6.0)

      Tool

    5. visually inspected to confirm anatomical accuracy

      Method

    6. the new segment tool embedded in SPM 12 software

      Tool

    7. rest software

      Tool

    1. WMH volume was examined as a percentage of166ICV

      Stat process

    2. adjusted for age159and

      Stat method

    3. 3dRegAna, AFNI

      Software tool

    4. sigma 2 mm

      analysis parameter

    5. Voxelwise GM density was calculated using the145standard FSL VBM package

      Software

    1. subject’s age, sex, and eTIV were considered in the matrix design in the SPM12

      stat detail

    2. extent threshold was set at 250 voxels

      Stat detail

    3. SPM12 using an uncorrected threshold of p < 0.001

      Stat detail

    4. Statistical Package for Social Sciences software ver. 16.0

      Stat software

    5. p-value of less than 0.05 was used for group comparisons, and the extent threshold was set at 50 voxels

      Stat Parameters

    6. SPM12

      Stat software

    7. adjusted for estimated total intracranial volume (eTIV) and age

      Stat: Age and ICV adjustment

    8. FreeSurfer

      Tool

    9. 5.3.0

      FreeSurfer version

    10. 8-mm full-width-half-maximum Gaussian smoothing kernel

      Parameter

    11. SPM12

      Tool

    12. MRICRON

      Software tool

    13. VBM technique implemented in the CAT toolbox
    14. NIfTI

      data format

  3. Mar 2018
    1. For investigating group differences, we run voxel-wise linear regression in the form:X~A + βgroupGroup + βageAge + βsexSex + βscan−chScan − ch + βintervalInterval + βICVICV + εwhere X is the Jacobian determinant value at a given position, A is the constant Jacobian determinant term, the βs are the covariate regression coefficients, and ε is an error term.

      Stat model

    2. ANTs Symmetric Normalization (SyN; (Avants et al., 2008))

      Software

    3. flirt (http://fsl.fmrib.ox.ac.uk)

      Software

    4. Brainsuite (http://brainsuite.org)

      Software

    5. (http://www.itksnap.org)

      Software

    1. SPSS version 20.0

      Stat software

    2. Student’s t-test.

      Stat test

    3. FreeSurfer 5.1.0

      Software

    4. Inbrain®, a Korea Food and Drug Administration (KFDA)-cleared software and a registered trademark of MIDAS Information Technology Co., Ltd., which performs fully-automated image analysis of brain structures

      Software

    1. Brain regions showing a significant interaction between group and Eyes Test score in the association with gray matter volume

      Result

    2. 1.5 × 1.5 × 1.5 mm and smoothed using a 12-mm full-width at half-maximum (FWHM) isotropic Gaussian kernel

      analysis parameters

    3. SPM81 and the VBM8 toolbox2 implemented in MATLAB R2012b

      Analysis tools

    4. analyzed using a t-test between groups and analysis of covariance (ANCOVA) with group (TD and ASD) as an effect-of-interest factor and age, sex and full-scale IQ as effect-of-no-interest covariates. A p-value < 0.05 was considered significant.

      stat method

    5. SPSS 16.0J

      Stat software

    1. we performed PLS (McIntosh et al., 1996) using PLSGUI7

      Software

    2. probabilistic cytoarchitectonic atlas included in the SPM Anatomy toolbox

      Software

    3. Automated Anatomical Labeling atlas (Tzourio-Mazoyer et al., 2002) included in the MRIcron software

      Software

    4. significance in both of these parametric and nonparametric analyses are reported. We also explored the effects of ASD subtype (Asperger’s disorder vs. PDD-NOS) using these predefined thresholds. The clusters that showed significant group difference (TD > ASD) were used as an inclusive mask.

      Stat details

    5. Permutation Analysis of Linear Models software

      Stat software

    6. VBM using a general linear model analysis, with group as the effect-of-interest factor and sex and age as the effect-of-no-interest covariates. The association between group difference and the volume of the gray matter was tested using T-statistics and reported as a Z-score after the T-value was transformed into the standard normal distribution. Voxels were deemed to be statistically significant if they reached the extent threshold of p < 0.05, after false-discovery rate (FDR) correction for multiple comparisons based on the topological FDR procedure (Chumbley and Friston, 2009), with a cluster-forming threshold (CFT) of p < 0.01 (uncorrected)

      Stat details

    7. with default settings

      parameters

    8. visual inspection of T1 images and confirmed no macroscopic lesions or artifacts in the images

      QA

    9. VBM8 toolbox

      Tool and version

    10. MATLAB R2012b

      Tool version

    1. MarsBaR toolbox

      Stat tool

    2. GingerAle

      tool

    3. Statistical Non-Parametric Mapping toolbox

      stat tool

    4. age as a covariate and the results were assessed on the basis of nonparametric cluster-wise inference, with a cluster-forming threshold of 0.005 and cluster-based correction for multiple comparisons such that pFWE < 0.05. In addition, we re-ported any results passing the cluster-forming threshold of p < 0.005

      stat details

    5. GingerAle

      software

    6. Anatomic Labelling (AAL) system in the WFU pickatlas (www.nitrc.org/projects/wfu_pickatlas/).

      software

    7. controlling for age

      stat detail

    8. MarsBaR toolbox (http://marsbar.sourceforge.net/)

      stat analysis

    9. Statistical Non-Parametric Mapping toolbox (http://warwick.ac.uk/snpm), with a cluster-forming threshold of 0.005 and a family-wise error (FWE) of 0.05

      stat method

    10. included age as a covariate

      stat detail

    11. Neurosynth software (neurosynth.org) to conduct a reverse inference meta-analysis of previously published studies with the predefined search term “theory mind.”

      analysis approach

    12. smoothed with an iso-tropic 8 mm full-width at half-maximum

      Analysis detail

    13. final voxel size of 1.5 × 1.5 ×1.5  mm3; segmentation into grey matter, white matter and cerebrospinal fluid; and modulation by the nonlinear com-ponent only for volume changes during spatial normalization to identify regional differences in grey matter volume cor-rected for individual brain size

      analysis detail

    14. MATLAB 2014

      Software

    15. SPM8

      Software

    16. VBM

      Software

    1. IBM SPSS Statistics® version 22.

      Stat software

    2. z-distribution Monte Carlo simulation with 10,000 repeats was then applied to correct for multiple comparisons using a cluster-forming threshold set at p < .05.

      Stat method

    3. FreeSurfer version 6.0

      Software and version

    4. 3D MP-RAGE sequence (TR/TE:2300/3.03 ms; flip angle: 90; 192 sagittal slices with 1 mm3 voxel size

      Imaging details

    5. 3 T Siemens Skyra scanner with a 20-channel head coil

      Acq Details