852 Matching Annotations
  1. Jul 2021
    1. NIMH Workshop on Naturalistic Stimuli and Individual Differences

      NIMH Workshop on Naturalistic Stimuli and Individual Differences; August 2, 2021; Virtual Workshop

    1. Beyond the Bench: The Broader Impact of Rigorous Research; July 12, 2021 11:00 AM - 3:30 PM ET; Virtual Workshop

  2. Jun 2021
  3. May 2021
    1. Clowder "All Paws" 2021; Monday, June 21 - Wednesday, June 23, 2021; Online Meeting

    1. Open Science Best Practices Workshop: Learn how to access and query the C-BIG Repository

      Open Science Best Practices Workshop: Learn how to access and query the C-BIG Repository; June 10, Noon EDT; Virtual

    1. KREMBIL CENTRE FOR NEUROINFORMATICS SUMMER SCHOOL; JULY 5-14, 2021; Summer School

  4. Apr 2021
    1. The Statistical Methods in Imaging Conference 2021Virtual Event, May 17-19, 2021

      The Statistical Methods in Imaging Conference 2021; May 17-19, 2021; Virtual Event

    1. The Future of Open Science: The Need to Change Culture to Change Science

      The Future of Open Science: The Need to Change Culture to Change Science; Mon, Apr 26, 2021 12:00 PM - 1:00 PM EDT; Moderated Conversation

  5. iitdbgroup.github.io iitdbgroup.github.io
    1. Workshop on Provenance for Transparent Research

      Workshop on Provenance for Transparent Research; July 19-22, 2021; Workshop

    1. Nilearn-Nibabel Dev Days

      Nilearn-Nibabel Dev Days; 5-7 May, 2021; Development Days

    1. no difference between groups

      volume increase NSC with diagnosis (ASD -> typically developing control) hemisphere: bilateral structure: hippocampus

    2. Bilaterally, hippocampus volume increased from baseline to follow-up in both ASD and TDC

      volume increases with time (baseline -> 2yr followup) Diagnosis: ASD structure: hippocampus hemisphere: bilateral

      volume increases with time (baseline -> 2yr followup) Diagnosis: typically developing control structure: hippocampus hemisphere: bilateral

  6. Mar 2021
    1. Inclusion criteria for matched control participants were no ongoing eating disorders, no neurologic disorders, no ongoing diseases and no medication

      matching

    2. female

      sex

    3. 25 patients accepted

      N patients

    4. Autism-spectrum Quotient (AQ) questionnaire

      Assessment

    5. Depressive symptoms were assessed in all patients using the Beck Depression Inventory (BDI)

      Assessment

    6. ongoing eating disorders were assessed using the Structured Clinical Interview (SCID-I) for DSM-IV.

      HC assessment

    7. written questionnaire

      HC assessment

    8. excluded

      Exclusion criteria

    9. diagnosis of anorexia nervosa according to DSM-IV

      DX Criteria

    10. psychiatrist

      Clinical assessor

    11. recruited consecutively from the in- and outpatient specialist Anorexia-Bulimia unit at the Queen Silvia Children’s University Hospital in Gothenburg, Sweden

      recruitment

    12. 16–25 years

      age

    13. anorexia nervosa

      DX

    1. NIH Data Sharing and Reuse Seminar Series

      NIH Data Sharing and Reuse Seminar Series; Noon, EST, March 12, 2021; Webinar

  7. Feb 2021
  8. Jan 2021
  9. Dec 2020
    1. machine learning in medicine

      Machine Learning in Medicine: A virtual Seminar; Various Times; Seminar

    1. Winter School of the Helmholtz International BigBrain Analytics and Learning Laboratory (HIBALL)

      Winter School of the Helmholtz International BigBrain Analytics and Learning Laboratory (HIBALL); 3-4 February 2021; Online Virtual Meeting

    1. No significant differences were found in the right ACG volume.

      volume NSC with diagnosis (no psychiatric diagnosis -> pediatric bipolar disorder) structure: anterior cingulate gyrus age: children hemisphere: right

      volume NSC with diagnosis (autism spectrum disorder -> pediatric bipolar disorder) structure: anterior cingulate gyrus age: children hemisphere: right

    2. The left ACG volume was significantly smaller in the BD group compared to the NP (p=0.004) and ASD (p=0.006) groups.

      volume decreases with diagnosis (no psychiatric diagnosis -> pediatric bipolar disorder) structure: anterior cingulate gyrus age: children hemisphere: left

      volume decreases with diagnosis (autism spectrum disorder -> pediatric bipolar disorder) structure: anterior cingulate gyrus age: children hemisphere: left

    1. There were no significant group asymmetry differences, nor volume differences in the caudate, putamen, and globus pallidus.

      asymmetry NSC with diagnosis structure: putamen age: youths

      volume NSC with diagnosis structure: caudate age: youths

      volume NSC with diagnosis structure: globus pallidus age: youths

      volume NSC with diagnosis structure: putamen age: youths

      asymmetry NSC with diagnosis structure: caudate age: youths

      asymmetry NSC with diagnosis structure: globus pallidus age: youths

    2. Youths with BPD had a trend for larger right nucleus accumbens (NA) volumes (p = 0.089).

      volume increases with diagnosis (healthy controls -> bipolar disorder) hemisphere: right structure: nucleus accumbens

    3. the prepubertal group had significantly larger total NA (p = 0.035) versus healthy controls, while the pubertal group did not show significant differences in the NA versus healthy controls.

      volume increases with diagnosis (healthy controls -> bipolar disorder) hemisphere: total structure: nucleus accumbens group: prepubertal

      volume NSC with diagnosis (healthy controls -> bipolar disorder) hemisphere: total structure: nucleus accumbens group: pubertal

    1. this effect was driven predominantly by the female bipolar disorder subjects

      volume decreases with diagnosis (healthy comparison subjects -> bipolar disorder) sex: female structure: hippocampus age: youths (6-16 years)

      volume NSC with diagnosis (healthy comparison subjects -> bipolar disorder) sex: male structure: hippocampus age: youths (6-16 years)

    2. subjects with bipolar disorder had smaller hippocampal volumes

      volume decreases with diagnosis (healthy comparison subjects -> bipolar disorder) structure: hippocampus age: youths (6-16 years)

    3. both male and female youths with bipolar disorder had significantly smaller cerebral volumes

      volume decreases with diagnosis (healthy comparison subjects -> bipolar disorder) sex: female structure: cerebral volume age: youths (6-16 years)

      volume decreases with diagnosis (healthy comparison subjects -> bipolar disorder) sex: male structure: cerebral volume age: youths (6-16 years)

    4. No significant hemispheric effects were seen

      <dependent variable> increases/decreases with <independent variable> (condition1 -> condition2) structure: hippocampus hemisphere: left

      <dependent variable> shows no change with <independent variable> structure: hippocampus hemisphere: left

  10. Nov 2020
    1. Recent Advances in Statistical Analysis of Imaging Data; December 4 – December 5, 2020; Fully Virtual -- Zoom Based Single Track Meeting

    1. Neuroscience Gateway Using NEURON and EEGLAB Webinar

      Neuroscience Gateway Using NEURON and EEGLAB Webinar; Friday, November 20, 2020 9:30 AM - 12:30 PM PST; Virtual Webinar

  11. Oct 2020
    1. XSEDE HPC Workshop: OpenMP

      XSEDE HPC Workshop: OpenMP; November 3, 2020; Zoom Workshhop

  12. Sep 2020
    1. Biological Data Science November 4 - 6, 2020 Virtual

      Biological Data Science; November 4 - 6, 2020; Virtual Meeting

    1. Addressing Neuroimaging Challenges Across Populations and Settings

      Addressing Neuroimaging Challenges Across Populations and Settings; September 21-22, 2020; Virtual only via tele/videoconference

  13. Aug 2020
    1. Beyond Statistical Significance: Finding Meaningful Effects

      Beyond Statistical Significance: Finding Meaningful Effects; Sept 2, 2020, 10am-6pm ET; Virtual Meeting

    1. Workshop On Open Citations And Open Scholarly Metadata; 9 Sep 2020, 15-18 CET; Online Event

    1. Big Neuroscience Data: Opportunities and Challenges

      Big Neuroscience Data: Opportunities and Challenges; 1:30 AM – 3:30 AM EDT Tuesday Sep 1st, 2020; On Line

  14. Jul 2020
    1. voxel-based morphometry

      As a paper that cites 'voxel-based morphometry' as a technique, it is a candidate for the Monthly Morphometry Report. Identified in auto-search 7/11/15.

    2. progressive supranuclear palsy (PSP)

      Diagnosis Term: progressive supranuclear palsy: http://www.ncbi.nlm.nih.gov/mesh/68013494

    3. Parkinson's disease (PD)

      Diagnosis Term: Parkinson's disease: http://www.ncbi.nlm.nih.gov/mesh/68010300

    4. basal ganglia

      Anatomic Term:

    5. cortical motor areas

      anatomic term

    6. A functional magnetic resonance imaging (fMRI) force production paradigm

      fMRI task statement

    7. We found that PSP and PD share reduced functional activity of the basal ganglia and cortical motor areas, but this is more pronounced in PSP than in PD.

      Result statement: fMRI

    8. In PSP the frontal regions are underactive

      result statement: fMRI

    9. the posterior parietal and occipital regions are overactive as compared with controls and PD

      result statement, referring to in PSP: fMRI

    10. Crus I and lobule IX are hyperactive in PSP only

      result statement: fMRI

    11. Reductions in gray and white matter volume are specific to PSP

      result statement: vbm

    12. lobules I through IV, V, and VI of the cerebellum are hypoactive in PSP and PD

      result statement: fMRI

    13. frontal regions

      anatomic term, related to a finding

    14. posterior parietal

      anatomic term, related to a finding

    15. occipital regions

      anatomic term, related to a finding

    16. lobules I through IV, V, and VI of the cerebellum

      anatomic terms, related to a finding

    17. Crus I

      anatomic term related to a finding

    18. lobule IX

      anatomic term, related to a finding

    19. caudate

      anatomic term, result, prediction

    20. superior frontal gyrus

      anatomic term, result, prediction

    21. the functional status of the caudate as well as the volume of the superior frontal gyrus predict clinical gait and posture measures in PSP

      finding statement: parameter (clinical feature) prediction

    22. clinical gait

      clinical feature

    23. posture

      clinical feature

    24. MMR Summary:

      See also: https://www.nitrc.org/plugins/mwiki/index.php/mmr:26148135

      Diagnostic Groups: PSP, PD & CTL

      Methods: VBM, fMRI (force production paradigm)

      Findings:

      fmri 1) We found that PSP and PD share reduced functional activity of the basal ganglia and cortical motor areas, but this is more pronounced in PSP than in PD.

      fmri 2) In PSP the frontal regions are underactive

      fmri 3) [In PSP] the posterior parietal and occipital regions are overactive as compared with controls and PD

      fmri 4) lobules I through IV, V, and VI of the cerebellum are hypoactive in PSP and PD

      fmri 5) Crus I and lobule IX are hyperactive in PSP only

      vbm 1) Reductions in gray and white matter volume are specific to PSP

      clinical 1) status of the caudate as well as the volume of the superior frontal gyrus predict clinical gait and posture measures in PSP

    1. Neuroferritinopathy

      disease term

    2. 3D-T1w and quantitative T2 whole brain MRI scans

      acquisition details

    3. 10 clinically symptomatic patients with the 460InsA FTL mutation and 10 age-matched controls

      Subject groups: 10 FTL 10 CTL

    4. Voxel-based morphometry (VBM)

      Analysis method: VBM. MMR Candidate

    5. voxel-based relaxometry (VBR)

      Analysis method

    6. Clinical assessment using the Unified Dystonia Rating Scale (UDRS) and Unified Huntington's Disease Rating Scale (UHDRS) was undertaken in all patients

      Clinical measures

    7. Iron deposition in the caudate head and cavitation in the lateral globus pallidus correlated with UDRS score (p < 0.001).

      Result statement 2:

      Finding: significant What: correlation With: iron deposition: caudate, clinical: UDRS Who: all subjects

      Finding: significant What: correlation With: cavitation: lateral globus pallidus, clinical: UDRS Who: all subjects

    8. There were no differences between groups with VBR

      Finding statement 3:

      Finding: no difference What: VBR With: all regions Who: FTL versus CTL

    9. Voxel-based analysis in neuroferritinopathy expands the phenotype and determines radiological correlates of disease severity.
    10. VBM detected significant tissue changes within the substantia nigra, midbrain and dentate together with significant cerebellar atrophy in patients (FWE, p < 0.05)

      Result statement 1: Finding: 'significant tissue changes' Analysis: vbm Location: 'substantia nigra, midbrain and dentate' Groups: FTL compared to CTL

      Finding Observation Measure Locations/Measures Group/Comparison vbm 1 significant tissue changes vbm substantia nigra FTL relative to CTL vbm 1 significant tissue changes vbm midbrain FTL relative to CTL vbm 1 significant tissue changes vbm dentate FTL relative to CTL vbm 1 decrease vbm cerebellum FTL relative to CTL

      Finding: 'atrophy' (volume reduction) Analysis: vbm Location: 'cerebellum' Groups: FTL compared to CTL

    1. voxel-based morphometry
    2. clinical data
    3. depressive patients without anxiety disorder (DP group, n = 18)
    4. The DP group showed decreased GMV in the left insula (INS) and left triangular part of the inferior frontal gyrus when compared to the NC group.

      Observation: Decreased Volume AnalysisMethod: volume Location: Left Insula SubjectGroups: DP compared to NC

      Observation: Decreased Volume AnalysisMethod: volume Location: left triangular part of the inferior frontal gyrus (pars triangularis) SubjectGroups: DP compared to NC

    5. The DPA group showed greater GMV in the midbrain, medial prefrontal cortex, and primary motor/somatosensory cortex when compared to the NC group

      Observation: Increased Volume AnalysisMethod: volume Location: midbrain SubjectGroups: DPA compared to NC

      Observation: Increased Volume AnalysisMethod: volume Location: medial prefrontal cortex SubjectGroups: DPA compared to NC

      Observation: Increased Volume AnalysisMethod: volume Location: primary motor/somatosensory cortex SubjectGroups: DPA compared to NC

    6. the DPA group showed greater GMV than the DP group in the frontal, INS, and temporal lobes

      Observation: Increased Volume AnalysisMethod: volume Location: frontal lobe SubjectGroups: DPA compared to DP

      Observation: Increased Volume AnalysisMethod: volume Location: Insula SubjectGroups: DPA compared to DP

      Observation: Increased Volume AnalysisMethod: volume Location: temporal lobe SubjectGroups: DPA compared to DP

    7. Most gray matter anomalies were significantly correlated with depression severity or anxiety symptoms.

      Observation: significant AnalysisMethod: correlation Location: Volume:most gray matter anomalies, Clinical: depression severity or anxiety symptoms SubjectGroups: DPA and DP

    8. region-of-interest analyses of gray matter volume (GMV)
    9. normal controls (NC group, n = 28)
    10. depressive patients with anxiety disorder (DPA group, n = 20)
    1. clinical high risk (CHR) for psychosis
    2. self-reported and interviewer-rated measures of social functioning
    3. voxel based morphometry (VBM)
    4. the CHR group had less GMV in the left postcentral gyrus, bilateral parahippocampual gyri, and left anterior cingulate cortex

      Observation: reduced volume AnalysisMethod: vbm Location: left postcentral gyrus SubjectGroups: CHR compared to HC

      Observation: reduced volume AnalysisMethod: vbm Location: bilateral parahippocampual gyri SubjectGroups: CHR compared to HC

      Observation: reduced volume AnalysisMethod: vbm Location: left anterior cingulate cortex SubjectGroups: CHR compared to HC

    5. Reduced GMV in the postcentral gyrus and the anterior cingulate was related to self-reported social impairment across the whole group

      Observation: related AnalysisMethod: correlation Location: VBM:postcentral gyrus, clinical:self-reported social impairment SubjectGroups: All subjects

      Observation: related AnalysisMethod: correlation Location: VBM:anterior cingulate, clinical:self-reported social impairment SubjectGroups: All subjects

    1. In summary, we found that human males of all ages exhibit a larger HCV than females, but adjusting for individual differences in TBV or ICV results in no reliable sex difference. The frequent claim that women have a disproportionately larger hippocampus than men was not supported
    1. adolescent patients with severe MDD (n=20, mean age=16.0, range=15-18 years)

      Patient Group

    2. control sample of matched healthy adolescents (n=21, mean age= 16.6, range=15-18 years

      Control group

    3. Structural MRI data were analyzed using voxel-based morphometry (VBM)

      Morphometry Method

    4. MDD patients showed smaller hippocampal volumes compared to healthy adolescents.

      Result 1

    5. Higher levels of childhood maltreatment were associated with smaller hippocampal volumes in both depressed patients and healthy controls

      Result 2

    1. brain MRI scans at two time points 24 months apart

      Scan Interval

    2. sustained abstainers/light drinkers (N = 45)

      Group 1

    3. sustained heavy drinkers (N = 84)

      Group 2

    4. Gray matter volumetric change (GMV-c) maps were derived using the longitudinal DARTEL pipeline as implemented in SPM12

      Method SPM

    5. significant decline in GMV in both groups across the 2 year followup period

      Result 1

    6. tissue loss in the sustained heavy drinking group was more significant, larger per region, and more widespread across regions compared to abstainers/light drinkers

      Result 2

    1. 106 children (M = 10 years 1 month, SD = 16 months; 40 females) enrolled in primary school: 57 were healthy very preterm children (10 children born 24-27 completed weeks' gestation (extremely preterm), 14 children born 28-29 completed weeks' gestation, 19 children born 30-31 completed weeks' gestation (very preterm), and 14 born 32 completed weeks' gestation (moderately preterm)) all born appropriate for GA (AGA) and 49 term-born children

      Groups

    2. voxel-based morphometry

      Method

    3. children born <28 completed weeks' gestation had less gray matter volume (GMV) and white matter volume (WMV) and poorer cognitive functions including decreased full scale IQ, and processing speed

      Result 1

    4. Differences in GMV partially mediated the relationship between GA and full scale IQ in preterm born children.

      Result 2

    1. We analyzed magnetic resonance imaging (MRI) data from a large longitudinal sample (270 participants, 678 scans) using an automated segmentation tool and mixed models to delineate the development of hippocampal subregion volumes from childhood to adulthood.
    1. average neuronal density of the same 60 loci was significantly higher in the male group than in the female group, and the corresponding mean male-to-female ratios were 1.18 in the right and 1.13

      neuronal density difference

    2. cortical thickness of the 60 loci examined was similar in males and females

      No Thickness difference

    1. Overall, there is increasing evidence that specific features (for example, functional connectivity, gray matter volume) of brain regions comprising the salience and default mode networks can be used to discriminate ASD from typical development.

      Conclusion 1

    2. At present, however, the field has yet to identify reliable and reproducible biomarkers for these disorders, and must address issues related to clinical heterogeneity, methodological standardization and cross-site validation before further progress can be achieved.

      Conclusion 2

  15. Jun 2020
  16. May 2020
  17. Apr 2020
  18. Mar 2020
    1. EEGLAB 2020

      EEGLAB 2020; MAY 27 - JUNE 5, 2020; UC SAN DIEGO SUPERCOMPUTER CENTER

  19. Feb 2020
    1. Machine Learning for Healthcare 2020; August 6-8, 2020; Durham, NC, USA

    1. FSCI2020 - August 3 - 7 - UCLA - Los Angeles, California USA

      FSCI2020; August 3 - 7, 2020; Los Angeles, CA USA

  20. Jan 2020
    1. NLM Reproducibility Workshop Menu About Dates

      NLM REPRODUCIBILITY in Bioinformatics WORKSHOP; May 15 – May 17, 2019; Bethesda, MD USA

    1. SPM8

      Tool

    2. VBM8

      Tool

    3. ABIDE

      Data Source

    4. Total brain and grey matter volumes were enlarged by approximately 1–2 % in ASD; however, the effect reached statistical significance in only the All Subjects cohort.

      Claim

    1. NIH Workshop on the Role of Generalist Repositories to Enhance Data Discoverability and Reuse; February 11–12, 2020; Bethesda, MD USA

    1. FENS Forum of Neuroscience; 11-15 July, 2020; Glasgow, UK