1 Matching Annotations
- May 2017
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dharmacon.gelifesciences.com dharmacon.gelifesciences.com
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MGC Fully Sequenced Human CEL cDNA
Warning, this reagent is not what it appears to be! Please see Xia et al, JBC 2017: doi:10.1074/jbc.A116.734384 "We recently learned that the cDNA encoding CEL purchased from OpenBiosystems (clone ID 5187959; GenBankTM accession no. BC042510.1) for this work contains a three-base pair in-frame deletion resulting in p.E365del. (The correct sequence should be 356NKGNKKVTEEDFYKLVSEFTITKGL380 and not 356NKGNKKVTE-DFYKLVSEFTITKGL380.) p.E365 is conserved in most primates. The residue is located in a surface loop of the CEL globular domain distant from the catalytic site and the bile acid-binding site."
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