5 Matching Annotations
  1. Dec 2017
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oestrogen up-regulates interleukin-21 production by CD4+ T lymphocytes in patients with systemic lupus erythematosus
    1
    1. lruddy 01 Dec 2017
      The major role of this cytokine is to promote B-cell proliferation, plasma cell differentiation, and antibody production

      IL-21 promotes: -B cell proliferation -plasma membrane differentiation -AB production

      Immunology2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC4107667/
  3. Oct 2017
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis
    4
    1. lruddy 02 Oct 2017
      sclerosis

      abnormal hardening of tissue

      Immunology2017
    2. lruddy 02 Oct 2017
      mesangial cells

      mesangial cells are responsible for contraction of blood vessels

      Immunology2017
    3. lruddy 02 Oct 2017
      negatively

      repressor is binding to prevent transcription

      Immunology2017
    4. lruddy 02 Oct 2017
      ubiquitin-editing enzyme

      ubiquitin is bound to IkB in the cascade towards transcription of TNF-alpha

      Immunology2017
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    ncbi.nlm.nih.gov/pmc/articles/PMC4482407/