2 Matching Annotations
  1. Jul 2018
    1. On 2014 Feb 04, Martine Crasnier-Mednansky commented:

      Comment concerning the AUTHOR’S CORRECTION:

      In 1942, Jacques Monod indeed reported that associating any compound A (Glucose, Mannose, Fructose, Mannitol) with any compound B (the 'less preferred' carbon source) invariably resulted in diauxic growth with Bacillus subtilis. With Escherichia coli, he reported a diauxic growth with Glucose or Mannitol in combination with the 'less preferred' carbon source, but not with Fructose or Mannose. Therefore, Monod labeled Fructose and Mannose as 'indifférents' sugars for E. coli.

      However, in his 1947 publication entitled 'The phenomenon of enzymatic adaptation' Monod emphasized what was true for B. subtilis was "equally true with many Escherichia coli strains, although with others, Fructose and Mannose are often found not to produce diauxic growth in any combination."

      Researchers should therefore be aware that with E. coli production of diauxie is most likely strain-dependent when Fructose or Mannose is used in combination with a 'less preferred carbon source'. The strains used by the present reviewer did not produced diauxie with Fructose and a 'less preferred carbon source' (in agreement with Monod 1942 publication) but diauxie was observed with fruR strains (lacking the fructose repressor) in the presence of Fructose and a 'less preferred carbon source'. Therefore the widely used E. coli strain MC4100 which has been reported to be disrupted for fruR Ferenci T, 2009 should exhibit diauxie with Fructose and any compound B.


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  2. Feb 2018
    1. On 2014 Feb 04, Martine Crasnier-Mednansky commented:

      Comment concerning the AUTHOR’S CORRECTION:

      In 1942, Jacques Monod indeed reported that associating any compound A (Glucose, Mannose, Fructose, Mannitol) with any compound B (the 'less preferred' carbon source) invariably resulted in diauxic growth with Bacillus subtilis. With Escherichia coli, he reported a diauxic growth with Glucose or Mannitol in combination with the 'less preferred' carbon source, but not with Fructose or Mannose. Therefore, Monod labeled Fructose and Mannose as 'indifférents' sugars for E. coli.

      However, in his 1947 publication entitled 'The phenomenon of enzymatic adaptation' Monod emphasized what was true for B. subtilis was "equally true with many Escherichia coli strains, although with others, Fructose and Mannose are often found not to produce diauxic growth in any combination."

      Researchers should therefore be aware that with E. coli production of diauxie is most likely strain-dependent when Fructose or Mannose is used in combination with a 'less preferred carbon source'. The strains used by the present reviewer did not produced diauxie with Fructose and a 'less preferred carbon source' (in agreement with Monod 1942 publication) but diauxie was observed with fruR strains (lacking the fructose repressor) in the presence of Fructose and a 'less preferred carbon source'. Therefore the widely used E. coli strain MC4100 which has been reported to be disrupted for fruR Ferenci T, 2009 should exhibit diauxie with Fructose and any compound B.


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.