On 2016 Oct 25, FREDERICK DOMANN commented:

U87MG cells are not what they used to be !!

The U87MG cells used in this study were obtained from ATCC. A recent (2016) DNA sequencing study by Bengt Westermark revealed that these cells were likely contaminated at some point as their genetic signature did not match the parental tumor of their origin. Below are links to the story and an interview with Dr. Westermark.

http://www.igp.uu.se/research/neuro-oncology/bengt-westermark/

http://www.the-scientist.com/?articles.view/articleNo/46929/title/Popular-Tumor-Cell-Line-Contaminated/

http://stm.sciencemag.org/content/8/354/354re3

On 2016 Oct 25, FREDERICK DOMANN commented:

U87MG cells are not what they used to be !!

The U87MG cells used in this study were obtained from ATCC. A recent (2016) DNA sequencing study by Bengt Westermark revealed that these cells were likely contaminated at some point as their genetic signature did not match the parental tumor of their origin. Below are links to the story and an interview with Dr. Westermark.

http://www.igp.uu.se/research/neuro-oncology/bengt-westermark/

http://www.the-scientist.com/?articles.view/articleNo/46929/title/Popular-Tumor-Cell-Line-Contaminated/

http://stm.sciencemag.org/content/8/354/354re3