On 2014 Feb 01, Jan Tunér commented:

In this study, a 6 mW HeNe laser or a placebo HeNe laser was used to treat leg ulcers twice weekly for 12 weeks. The stated dose was 4 J/cm2. The area of the ulcers varied from 3 cm2 to 32 cm2. To achieve the stated dose, the treatment time of each session of therapy would thus have had to vary from 33 minutes to 6 hours. It is questioned that the patients really would have been treated for 6 hours. The method by which the dose was calculated is therefore questionable. No indication is given of the method of treatment. If a scanning laser with an unexpanded beam was used, the power density would have been about 0.15 W/cm2. If the beam was expanded to a diameter capable of illuminating the whole area of the ulcer at once, the power density when treating the largest ulcer would have been about 0.00019 W/cm2, which is close to the level of moonlight. Unless more parameters are accounted for, it is impossible to evaluate this study. The possibility of performing a double blind study with red light is also questionable. The authors have been reluctant to answer questions on this paper.

On 2014 Feb 01, Jan Tunér commented:

In this study, a 6 mW HeNe laser or a placebo HeNe laser was used to treat leg ulcers twice weekly for 12 weeks. The stated dose was 4 J/cm2. The area of the ulcers varied from 3 cm2 to 32 cm2. To achieve the stated dose, the treatment time of each session of therapy would thus have had to vary from 33 minutes to 6 hours. It is questioned that the patients really would have been treated for 6 hours. The method by which the dose was calculated is therefore questionable. No indication is given of the method of treatment. If a scanning laser with an unexpanded beam was used, the power density would have been about 0.15 W/cm2. If the beam was expanded to a diameter capable of illuminating the whole area of the ulcer at once, the power density when treating the largest ulcer would have been about 0.00019 W/cm2, which is close to the level of moonlight. Unless more parameters are accounted for, it is impossible to evaluate this study. The possibility of performing a double blind study with red light is also questionable. The authors have been reluctant to answer questions on this paper.