On 2013 Nov 07, Rafael Najmanovich commented:

Is there any measurement of how complete the network is? The proverbial 'known unknowns'? for example independent metabonomics studies coming up with several small molecules that don't appear in the network? not that every molecule must necessarily be a substrate or product in a reaction but most are.

On 2013 Nov 05, Pedro Mendes commented:

This yeast metabolic reconstruction has since been further improved by Dobson PD, 2010, Heavner BD, 2012 and Heavner BD, 2013. The up to date data set is available from http://yeast.sf.net/.

On 2013 Nov 05, Pedro Mendes commented:

This yeast metabolic reconstruction has since been further improved by Dobson PD, 2010, Heavner BD, 2012 and Heavner BD, 2013. The up to date data set is available from http://yeast.sf.net/.