- Jul 2018
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europepmc.org europepmc.org
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On 2014 Mar 30, Tero Kivelä commented:
Figure 4 in this paper raises a few questions:
1: The graph has 2 steps indicating 2 patients who died, and 5 ticks indicating 5 censored observations; this adds to 7, but 11 patients entered the study.
2.1: According to the text "Three patients have died from extrahepatic metastases at 2.5, 3, and 18 months posttreatment". The one who died at 3 months is not plotted.
2.2: According to the text "One patient was lost to follow-up after 2.5 months". This patient is not plotted.
2.3: If we add these two apparently non-plotted patients, the plot seems to account only for 9 of the 11 patients.
2.4: Adding these 2 patients to the plot would drop 1-year survival to 25%, and 50% mortality would be reached around 18 months.
3: According to the text "Of the remaining 8 patients in follow-up, 1 patient developed new hepatic lesions at 14 months posttreatment". If we deduct from the 11 patients who entered the study the 3 who died and the 1 who was lost to follow-up, only 7 patients remain.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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europepmc.org europepmc.org
-
On 2014 Mar 30, Tero Kivelä commented:
Figure 4 in this paper raises a few questions:
1: The graph has 2 steps indicating 2 patients who died, and 5 ticks indicating 5 censored observations; this adds to 7, but 11 patients entered the study.
2.1: According to the text "Three patients have died from extrahepatic metastases at 2.5, 3, and 18 months posttreatment". The one who died at 3 months is not plotted.
2.2: According to the text "One patient was lost to follow-up after 2.5 months". This patient is not plotted.
2.3: If we add these two apparently non-plotted patients, the plot seems to account only for 9 of the 11 patients.
2.4: Adding these 2 patients to the plot would drop 1-year survival to 25%, and 50% mortality would be reached around 18 months.
3: According to the text "Of the remaining 8 patients in follow-up, 1 patient developed new hepatic lesions at 14 months posttreatment". If we deduct from the 11 patients who entered the study the 3 who died and the 1 who was lost to follow-up, only 7 patients remain.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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